SAS Offers for Commercial Sphere

The increase of the transformation and biodegradation abilities of the microorganisms.

Code: IMC-S-00-0071-UMB

Institute of Molecular Biology

Contact Person:

Description:

  • Our results concerning the stress factor effects on the biodegradation potential of the bacterial cells suggest the possible cell activity increase after their exposure to adequate and appropriately applied stress factor. Continuation in this research can reveal more effective use of the bacterial cells in biotechnologies. The research could be orientate on the activity increase, e. g. of the different productive strains whether in food or pharmaceutical industry.
  • In our laboratories we prepare the efficient geneticaly modified microorganisms of which use in modern technologies for the contamination removal is for the time being on the start. It concerns of the yeast mutants, like Saccharomyces cerevisiae with over-production of the peroxid-active catalases. Their characteristics are suitable first of all for organic matter trace amount removal. Important substances of this type are phenols and organic hydrocarbons which represent oil contamination of the water.
  • Bacteria Escherichia coli surviving in the environment contaminated by cadmium are able essentially reduce its effective concentration in the cell. For this purpose they use the proteins able to bound cadmium into their structures. Protein F023.3 was identified as cadmium specific stress protein with possible ability to bound the cadmium ions. At present by genetic-engineerig methods we prepare the mutant E. coli strain with over-production of this protein. This assumed geneticaly modified bacterial strain could be used in biotechnology processes (bioreactor) during cadmium removal (bioaccumulation) from contaminated water or soil.

Inovation:

Utilization of efficient microorganisms prepared by genetic- engineering.

Application:

Environment.

State:

The prepared recombinant strains are before testing.

Cooperation:

Cooperation in the development of bioremediation procedures based on combination biological and non – biological principles.