RNDr. Zuzana Bednáriková, PhD.
amyloid aggregation of proteins, inhibitors, small molecules, Alzheimer´s disease
Watsonova 47
040 01 Košice
Slovak Republic
@:
My focus is studying the amyloid aggregation of proteins, which plays an important role in the pathogenesis of more than 50 severe and currently incurable diseases, such as Alzheimer's, Parkinson's, or type II diabetes.
I am devoted to understanding the mechanisms of the formation of protein amyloid aggregates and their structure.
During my PhD and postdoc research, I systematically investigated the effect of magnetic nanoparticles and small molecules on amyloid protein aggregation to find potential amyloid aggregation inhibitors.
Currently, I am more focused on studying the amyloid aggregation of proteins associated with the pathology of Alzheimer's disease and searching for compounds that can interfere with several targets, so-called multitargeted directed ligands.
I am devoted to understanding the mechanisms of the formation of protein amyloid aggregates and their structure.
During my PhD and postdoc research, I systematically investigated the effect of magnetic nanoparticles and small molecules on amyloid protein aggregation to find potential amyloid aggregation inhibitors.
Currently, I am more focused on studying the amyloid aggregation of proteins associated with the pathology of Alzheimer's disease and searching for compounds that can interfere with several targets, so-called multitargeted directed ligands.