Curriculum vitae
MUDr. Táňa Ravingerová, DrSc., FIACS
Táňa Ravingerová, MD, PhD, DSc, FIACS, Academician of the Learned Society of SlovakiaInstitute for Heart Research, Centre of Experimental Medicine, Slovak Academy of Sciences
Education
Doctor of Medicine, General Medicine, Russian Medical University, Moscow, RF;
PhD, Normal and pathological physiology, Comenius University, Bratislava, Slovakia;
DSc, Slovak Academy of Sciences, Bratislava, Slovakia
Affiliation
1978 – till present: Institute for Heart Research, Slovak Academy of Sciences, Bratislava, Slovakia (from 2018, IHR CEM SAS) - PhD student, scientist, senior scientist
Current position
Senior scientist at the Department of Cardiovascular Physiology and Pathophysiology, IHR CEM SAS
Fields of research interest
• Ischemic injury of the heart, antiiischemic protection; lifestyle-related diseases
• Cardiac adaptation, molecular mechanisms of innate cardioprotection
Publications/ SCI citations:
>170 publications (papers in CC journals and book chapters); >1500 citations. H-index 33.
http://orcid.org/0000-0002-8804-6964
Research achievements
- Lifestyle-related risk factors have a negative impact on the myocardial response to ischemia per se and reduce the effectivity of innate cardioprotective interventions.
- Adaptive potential of the myocardium can be restored by the modulation of the type and/or intensity of the adaptive (conditioning) stimulus.
- Activation of the transcription factor PPAR-alpha simulates the effect of preconditioning and protects the heart by means of up-regulation of PPAR “downstream“ metabolic genes of fatty acids metabolism and via non-metabolic effects.
- Age and gender determine cardiac response to ischemia as well as the efficiency of ischemic preconditioning that has been observed already during the period of maturation.
- Remote preconditioning is an effective and relatively simple tool to attenuate irreversible consequences of lethal injury preserving myocardial function and biophysical properties of cardiac mitochondria.
Scientific projects (leader/deputy)
International projects: European network COST projects on Cardioprotection – current EU Cardioprotection COST project CA 16225, bilateral COST (SR- Austria, SR-CR, SR-GR), projects VEGA SR and APVV.
Main international training and cooperation:
• Cardiovascular Research Laboratories, King´s College, London, UK (Dr. M. Curtis)
• Department of Physiology and Pharmacology, University of Strathclyde, Glasgow, Scotland (in the frames of European COST network) (Prof. J. Parratt)
• Institute of Medical Physics and Biophysics, University of Graz, Graz, Austria (Prof. B. Koidl)
Visiting professorship:
Department of Med. Physiology, Institute of Med. Biology, University of Tromsoe, Norway (with Prof. K. Ytrehus)
Inst. Cardiovasc. Sciences, St. Boniface Gen. Hosp. Res. Centre, Univ. Manitoba, Winnipeg, Canada (with Prof. N.S. Dhalla)
Teaching experience
Slovak Medical University in Bratislava – External lecturer in cardiovascular pathophysiology; Supervision of PhD, MSc. and Bc. students at: Faculties of Medicine, Pharmacy, Natural Sciences, Faculty of Mathematics, Physics and Informatics, Comenius University in Bratislava.
Other professional activities
International Academy of Cardiovascular Sciences (IACS) – Elected
member of the Executive Council of IACS, Vice-President of the IACS European Section (IACS-ES). Council member and Fellow: IACS-ES. Slovak Physiological Society Honorary member; Czech-Slovak Working Group on Experimental Cardiology - Council member. Member of the Evaluation Commissions for PhD defense, habilitation, and inauguration procedures at home and abroad. Member of the Grant Evaluation Commission of Slovakia (VEGA SR), Organization of several European meetings of IACS-ES, meetings of ISHR-ES, and national physiological and cardiological meetings.
Awards and distinctions
Medals of the Slovak Cardiological Society (2001); Slovak Physiological Society & Slovak Medical Association (2011, 2017); Jan Jessenius Medal of the Slovak Academy of Sciences (2012), Medal of SAS for the Support of Science (2016); Distinguished Service Award of the IACS (2013); IACS-ES Award for Excellence in Cardiovascular Sciences (2015), Elected Member of the European Academy of Sciences and Arts (2015) and the Learned Society of the Slovakia (2016). IACS “Distinguished Leadership Award in Cardiovascular Sciences” (2018), Honour Membership of SFyS (2021). IACS "Bohuslav Ostadal Award for Excellence in Cardiovascular Sciences" (2022).
Served as a Faculty Member at international scientific meetings in Europe (CR, France, Hungary, Serbia, Norway, Romania, Turkey, UK) and worldwide (Australia, India, Canada, Taiwan, Japan) and had more than 80 invited talks.
Married, two sons.
Phone: +421 903 419 337; e-mail: usrdravi@savba.sk, tatiana.ravingerova@savba.sk