Project
Institute of Chemistry
International Projects
GESDIA - Analysis of nucleic acids, proteins and metabolites as potential circulating biomarkers of pregnancy diabetes
Analýza nukleových kyselín, proteínov a metabolitov ako potenciálnych cirkulujúcich biomarkerov tehotenskej cukrovky
| Duration: | 1. 3. 2020 - 31. 12. 2022 |
| Program: | Medzivládna dohoda |
| Project leader: | Ing. Katrlík Jaroslav PhD. |
GM-INHIB - Design, synthesis and characterization of efficient mannosidase inhibitors related to iminosugars and glycoconjugates
Dizajn, syntéza a charakterizácia účinných inhibítorov manozidáz na báze iminosacharidov a glykokonjugátov
| Duration: | 1. 1. 2020 - 31. 12. 2022 |
| Program: | JRP |
| Project leader: | Ing. Bella Maroš PhD. |
Ocean4Biotech - European transdisciplinary networking platform for marine biotechnology (Ocean4Biotech)
Európska multidisciplinárna platforma pre morskú biotechnológiu
| Duration: | 29. 10. 2019 - 28. 10. 2023 |
| Program: | COST |
| Project leader: | Mgr. Capek Peter PhD. |
GLYCONanoPROBES - Functional glyconanomaterials for the development of diagnostics and targeted therapeutic probes (GLYCONanoPROBES)
Funkčné glykonanomateriály pre vývoj sond pre diagnostiku a cielenú terapiu
| Duration: | 14. 3. 2019 - 13. 3. 2023 |
| Program: | COST |
| Project leader: | Ing. Katrlík Jaroslav PhD. |
INNOGLY - Innovation with Glycans: new frontiers from synthesis to new biological targets
Inovácie s glykánmi: nové horizonty od syntézy po nové biologické ciele
| Duration: | 8. 4. 2019 - 7. 4. 2023 |
| Program: | COST |
| Project leader: | Ing. Hricovíni Miloš PhD. |
YEAST4BIO - Non-conventional yeasts for the production of bioproducts (YEAST4BIO)
Nekonvenčné kvasinky na výrobu bioproduktov
| Duration: | 7. 11. 2019 - 6. 11. 2023 |
| Program: | COST |
| Project leader: | Ing. Šuchová Katarína PhD. |
SOURDOmICS - SOURDOugh biotechnology network towards novel, healthier and sustainable food and bIoproCesseS
Sieť kváskovej biotechnológie zameraná na nové, zdravšie a trvalo udržateľné potraviny a bioprocesy
| Duration: | 10. 4. 2019 - 9. 4. 2023 |
| Program: | COST |
| Project leader: | Ing. Košťálová Zuzana PhD. |
GREENERING - Green Chemical Engineering Network towards upscaling sustainable processes (GREENERING)
Sieť zeleného chemického inžinierstva smerom k zvyšovaniu udržateľnosti procesov
| Duration: | 14. 10. 2019 - 13. 10. 2023 |
| Program: | COST |
| Project leader: | Ing. Mastihubová Mária PhD. |
N/A - Synthesis of transition metal oxide nanoparticles, their plasma treatment and study of photoelectrical and photocatalytic properties
Syntéza nanočastíc oxidov prechodných kovov, ich plazmové spracovanie a štúdium fotoelektrických a fotokatalytických vlastností
| Duration: | 1. 1. 2021 - 31. 12. 2022 |
| Program: | Mobility |
| Project leader: | Ing. Mičová Júlia PhD. |
| Annotation: | One of biggest challenges for the scientific community is water resource ecology and particularly the removal of chemical and pharmaceutical residues, such as dyes, analgesics, antibiotic, antiepileptic and anti-Inflammatory drugs, from waste water. Probably the most serious situation nowadays is the water contamination with estrogen, the primary female sex hormone used in contraception. Nanoparticles, in particular metal oxide nanoparticles, have been used in water purification process [1]. Current attention is focused on various doped or surface-modified metal oxide thin films, particles and various nanocomposites. Thin films and nano or microstructures are a subject of a broad attention due to interesting optical, electric, piezoelectric and ferromagnetic properties [2]. The native point defects [3] and oxygen vacancies [4] have been studied including their sensitivity to hydrogen. Previous studies showed that the high temperature hydrogen annealing enhances significantly excitonic emission [5]. Our photoluminescence spectra of the plasma hydrogenated metal oxide nanorods have shown that the hydrogen plasma treatment passivates deep defects and enhances the band edge luminescence [6]. Infrared absorption spectra provide valuable insight into impurity complexes within a material. Ultimately, this can lead to a better understanding of the role these impurities play in influencing or controlling properties such as the majority-carrier type and concentration. Particularly, the bonding configuration of surface hydroxyl groups depends on the sample and treatment and it is not completely understood. The understanding of the role of hydrogen in metal oxides is technologically important because previous studies indicate that hydrogen is acting, in part, as an unintentional donor [7]. References [1] Y. Zhang, Y. Chen, P. Westerhoff, K. Hristovski, and J. C. Crittenden, “Stability of commercial metal oxide nanoparticles in water,” Water Research, vol. 42, no. 8–9, pp. 2204–2212, Apr. 2008, doi: 10.1016/j.watres.2007.11.036. [2] A. Janotti and C. G. Van de Walle, “Fundamentals of zinc oxide as a semiconductor,” Reports on Progress in Physics, vol. 72, no. 12, p. 126501, Dec. 2009, doi: 10.1088/0034- 4885/72/12/126501. [3] A. Janotti and C. G. Van de Walle, “Native point defects in ZnO,” Physical Review B, vol. 76, no. 16, Oct. 2007, doi: 10.1103/PhysRevB.76.165202. Document generated: 28.5.2020 10:58:48 3/ 14 Concept. [4] A. Janotti and C. G. Van de Walle, “Oxygen vacancies in ZnO,” Applied Physics Letters, vol. 87, no. 12, p. 122102, Sep. 2005, doi: 10.1063/1.2053360. [5] L. Procházková, T. Gbur, V. Čuba, V. Jarý, and M. Nikl, “Fabrication of highly efficient ZnO nanoscintillators,” Optical Materials, vol. 47, pp. 67–71, Sep. 2015, doi: 10.1016/j.optmat.2015.07.001. [6] T. Sekiguchi, N. Ohashi, and Y. Terada, “Effect of Hydrogenation on ZnO Luminescence,” Japanese Journal of Applied Physics, Part 2: Letters, vol. 36, pp. L289–L291, 1997. [7] C. G. Van de Walle, “Hydrogen as a Cause of Doping in Zinc Oxide,” Physical Review Letters, vol. 85, no. 5, pp. 1012–1015, Jul. 2000, doi: 10.1103/PhysRevLett.85.1012. |
LignoCOST - Establishment of a Pan-European network on the sustainable valorisation of lignin (LignoCOST)
Vybudovanie celoeurópskej siete pre udržateľné zhodnotenie lignínu
| Duration: | 4. 10. 2018 - 3. 10. 2022 |
| Program: | COST |
| Project leader: | Ing. Mastihuba Vladimír PhD. |
National Projects
Antimicrobial substances in honeybee larval food and their effect against American foulbrood pathogen
Antimikrobiálne látky v larválnej potrave včely a ich účinok voči patogénu moru včelieho plodu
| Duration: | 1. 1. 2019 - 31. 12. 2022 |
| Program: | VEGA |
| Project leader: | RNDr. Klaudiny Jaroslav PhD. |
GLYCO4BIO - Biochip systems for targeted glycan analysis of biomarkers for biomedical and biotechnological applications
Biočipové systémy na cielenú glykánovú analýzu biomarkerov pre biomedicínske a biotechnologické aplikácie
| Duration: | 1. 7. 2021 - 30. 6. 2025 |
| Program: | APVV |
| Project leader: | Ing. Katrlík Jaroslav PhD. |
CEMBAM - CEMBAM - Center of Medical Bio-additive Research and Production
CEMBAM - Centrum medicínskeho bioaditívneho výskumu a výroby
| Duration: | 1. 9. 2020 - 1. 6. 2023 |
| Program: | Štrukturálne fondy EÚ Výskum a inovácie |
| Project leader: | Ing. Katrlík Jaroslav PhD. |
BIOMEDIRES II - Center for Biomedical Research - BIOMEDIRES - II. phase
Centrum pre biomedicínsky výskum – BIOMEDIRES - II. etapa
| Duration: | 1. 1. 2020 - 1. 6. 2023 |
| Program: | Štrukturálne fondy EÚ Výskum a inovácie |
| Project leader: | RNDr. Mucha Ján CSc. |
CPT-ZOPA - Center for advanced therapies for chronic inflammatory diseases of the musculoskeletal system
Centrum pre pokročilé terapie chronických zápalových ochorení pohybového aparátu
| Duration: | 1. 6. 2020 - 1. 6. 2023 |
| Program: | Štrukturálne fondy EÚ Výskum a inovácie |
| Project leader: | Ing. Katrlík Jaroslav PhD. |
CoDe-X-TB - Computer-aided design of novel antituberculosis compounds and their experimental evaluation
Dizajn nových antituberkulóznych látok pomocou výpočtových metód a ich experimentálna evaluácia
| Duration: | 1. 8. 2021 - 30. 6. 2025 |
| Program: | APVV |
| Project leader: | Mgr. Kozmon Stanislav PhD. |
Design, synthesis and study of structure-activity-selectivity relationship of inhibitors against enzymes from GH38 family
Dizajn, syntéza a štúdium vzťahu medzi štruktúrou, aktivitou a selektivitou inhibítorov enzýmov z rodiny GH38
| Duration: | 1. 1. 2019 - 31. 12. 2022 |
| Program: | VEGA |
| Project leader: | Ing. Bella Maroš PhD. |
PreveLynch - Long-term strategic research and development focused on the occurrence of Lynch syndrome in the Slovak population and possibilities of prevention of tumors associated with this syndrome
Dlhodobý strategický výskum a vývoj zameraný na výskyt Lynchovho syndrómu v populácii SR a možnosti prevencie nádorov spojených s týmto syndrómom
| Duration: | 1. 1. 2020 - 1. 6. 2023 |
| Program: | Štrukturálne fondy EÚ Výskum a inovácie |
| Project leader: | RNDr. Mucha Ján CSc. |
Functionalized yeast polysaccharides – a prospective category of biocompatible substances with antimicrobial effectiveness.
Funkcionalizované kvasinkové polysacharidy – perspektívna kategória biokompatibilných látok s antimikrobiálnou účinnosťou.
| Duration: | 1. 1. 2021 - 31. 12. 2024 |
| Program: | VEGA |
| Project leader: | Ing. Čížová Alžbeta PhD. |
TYROSOLS - Chemoenzymatic synthesis of substances with pharmaceutical potential: Optimization of processes of phenylethanoid glycosides production
Chemoenzymatická syntéza látok s farmaceutickým potenciálom: optimalizácia procesov produkcie fenyletanoidných glykozidov
| Duration: | 1. 7. 2019 - 30. 6. 2023 |
| Program: | APVV |
| Project leader: | Ing. Mastihuba Vladimír PhD. |
AQUARAD - Chronic ionizing radiation compromises resistance to pests in wild aquatic plants: Discovery and validation of biochemical mechanisms
Chronické ionizujúce žiarenie narúša odolnosť vodných rastlín voči škodcom: Štúdium a validácia biochemických mechanizmov
| Duration: | 1. 8. 2021 - 30. 6. 2025 |
| Program: | APVV |
| Project leader: | Mgr. Baráth Peter PhD. |
KOREKAS - Immobilization and co-immobilization of viable whole-cell biocatalysts with enzyme cascades for production of chemical specialties, development of methods for their characterization and bioreactor engineering
Imobilizácia a koimobilizácia viabilných celobunkových biokatalyzátorov s enzýmovými kaskádami pre produkciu chemických špecialít, vývoj metód ich charakterizácie a bioreaktorové inžinierstvo
| Duration: | 1. 8. 2021 - 30. 6. 2025 |
| Program: | APVV |
| Project leader: | Ing. Bučko Marek PhD. |
TOXINOVAGE - Innovative approaches in toxicology of ageing
Inovatívne prístupy v toxikológii starnutia
| Duration: | 1. 7. 2019 - 30. 6. 2023 |
| Program: | APVV |
| Project leader: | Mgr. Baráth Peter PhD. |
Intensification of the development, production and non-invasive characterization of new immobilized whole-cell biocatalysts based on enzyme cascades for the production of chemical specialities
Intenzifikácia vývoja, produkcie a neinvazívnej charakterizácie nových imobilizovaných celobunkových biokatalyzátorov na báze enzýmových kaskád pre produkciu chemických špecialít
| Duration: | 1. 1. 2020 - 31. 12. 2023 |
| Program: | VEGA |
| Project leader: | Ing. Bučko Marek PhD. |
KaliBer - Calibration of the authigenic 10Be/9Be dating method for geochronological models of the latest Cenozoic of the Carpathian-Pannonian region
Kalibrácia metódy datovania autigénnym 10Be/9Be pre geochronologické modely najmladšieho kenozoika karpatsko-panónskeho regiónu
| Duration: | 1. 8. 2021 - 30. 6. 2025 |
| Program: | APVV |
| Project leader: | Ing. Chyba Andrej PhD. |
koforna - Co-transcriptional folding of pre-mRNA, model of structural motifs required for exon definition
Kotranskripčné formovanie pre-mRNA štruktúry, model štrukurálnych motívov nevyhnutných pre definíciu exónu
| Duration: | 1. 7. 2019 - 30. 6. 2023 |
| Program: | APVV |
| Project leader: | Mgr. Baráth Peter PhD. |
Metabolic changes associated with protein glycosylation disorders.
Metabolické zmeny spojené s poruchami glykozylácie proteínov
| Duration: | 1. 1. 2021 - 31. 12. 2024 |
| Program: | VEGA |
| Project leader: | Ing. Nemčovič Marek PhD. |
COMPEXYZYMES - Microbial enzymes degrading complex structures of plant xylans
Mikrobiálne enzýmy rozkladu komplexných štruktúr rastlinných xylánov
| Duration: | 1. 8. 2021 - 30. 6. 2025 |
| Program: | APVV |
| Project leader: | Mgr. Puchart Vladimír PhD. |
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Pokročilé analytické techniky v štruktúrnej analýze polysacharidov.
| Duration: | 1. 1. 2020 - 31. 12. 2022 |
| Program: | VEGA |
| Project leader: | Ing. Pätoprstý Vladimír PhD. |
Preparation and characterization of the multifunctional Fe3O4-ZnO-biopolymer nanocomposite with a focus on water purification
Príprava a charakterizácia multifunkčného nanokompozitu Fe3O4-ZnO-biopolymér so zameraním na čistenie vôd
| Duration: | 1. 1. 2020 - 31. 12. 2022 |
| Program: | VEGA |
| Project leader: | Ing. Mičová Júlia PhD. |
Génové manipulác - Preparation of new antibiotics and antitumor agents by manipulations of secondary metabolite genes and synthetic biology methods
Príprava nových antibiotík a protinádorových látok manipuláciami génov sekundárnych metabolitov a metódami syntetickej biológie
| Duration: | 1. 7. 2020 - 30. 6. 2024 |
| Program: | APVV |
| Project leader: | RNDr. Matulová Mária DrSc. |
Db12 - Protein Dbl2 as a novel regulator of genome stability and dynamics in fission yeast
Proteín Dbl2 ako nový regulátor stability a dynamiky genómu v kvasinkách Schizosaccharomyces pombe
| Duration: | 1. 7. 2019 - 30. 6. 2023 |
| Program: | APVV |
| Project leader: | Mgr. Baráth Peter PhD. |
Study of structural changes of complex glycoconjugates in the process of hereditary metabolic and civilization diseases.
Štúdium štruktúrnych zmien komplexných glykokonjugátov v procese dedičných metabolických a civilizačných ochorení.
| Duration: | 1. 1. 2020 - 30. 6. 2023 |
| Program: | Štrukturálne fondy EÚ Výskum a inovácie |
| Project leader: | RNDr. Mucha Ján CSc. |
LEBRE - Multidrug resistance of leukemia cells - Phenotype caused by interference of multimodal molecular reasons
Viaclieková rezistencia u leukemických buniek - fenotyp spôsobený interferenciou viacerých molekulárnych príčin
| Duration: | 1. 7. 2020 - 30. 5. 2024 |
| Program: | APVV |
| Project leader: | Ing. Katrlík Jaroslav PhD. |
Virtual screening, synthesis and study of the interactions of the potential glycosyltransferases inhibitors
Virtuálny skríning, syntéza a štúdium interakcií potenciálnych inhibítorov glykozyltransferáz
| Duration: | 1. 1. 2020 - 31. 12. 2023 |
| Program: | VEGA |
| Project leader: | Mgr. Kozmon Stanislav PhD. |
BIOTREAT - Development of bioimmunotherapeutics inspired by viral tricks: Treating despite the tricks
Vývoj bioimunoterapeutík inšpirovaný vírusovými trikmi: Liečenie aj napriek trikom
| Duration: | 1. 7. 2020 - 30. 6. 2024 |
| Program: | APVV |
| Project leader: | Mgr. Kóňa Juraj PhD. |
Development of nanostructured coatings with inacticating effect on viruses and bacteria for various types of flexible materials.
Vývoj nanoštrukturovaných povlakov s inaktivačným účinkom na vírusy a baktérie pre rôzne typy flexibilných materiálov.
| Duration: | 1. 1. 2021 - 30. 6. 2023 |
| Program: | Štrukturálne fondy EÚ Výskum a inovácie |
| Project leader: | RNDr. Mucha Ján CSc. |
Development of products by modification of natural substances and study of their mulimodal effects on COVID-19.
Vývoj produktov modifikáciou prírodných látok a štúdium ich multimodálnych účinkov na ochorenie COVID-19.
| Duration: | 1. 1. 2021 - 30. 6. 2023 |
| Program: | Štrukturálne fondy EÚ Výskum a inovácie |
| Project leader: | RNDr. Mucha Ján CSc. |
ProSaKiMi - Interaction between proteases, chaperones and kinases in stress condition cause by pathological conditions
Vzájomná inerakcia proteáz, šaperónov a kináz v mitochodriách pri strese spôsobenom patologickými stavmi
| Duration: | 1. 7. 2020 - 30. 6. 2024 |
| Program: | APVV |
| Project leader: | Mgr. Baráth Peter PhD. |
Projects total: 39