Project
Institute of Neuroimmunology
International Projects
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Alzheimer's Disease Diagnostics Innovation and Translation to Clinical Practice in Central Europe
| Duration: | 1. 1. 2023 - 31. 12. 2026 |
| Evidence number: | 101087124 — ADDIT-CE |
| Program: | Horizont Európa |
| Project leader: | doc. MVDr. Žilka Norbert DrSc. |
WesternND - Targeting Western Diet-Induced Neurodegeneration
Cielenie neurodegenerácie indukovanej západnou diétou
| Duration: | 1. 6. 2024 - 31. 5. 2027 |
| Program: | Horizont Európa |
| Project leader: | MSc. Basheer Neha PhD. |
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Double-edged sword of Parkinson's disease: the study of extracellular vesicles as a mediator of pathology spreading and uniquesource of early diagnostics data
| Duration: | 1. 5. 2023 - 30. 4. 2026 |
| Evidence number: | CRP/SVK22-04_Ec |
| Program: | ICGEB |
| Project leader: | MUDr. RNDr. Fričová Dominika PhD. |
INTERTAU - Integrative structural biology of pathological tau protein, an appealing therapeutic target for Alzheimer´s disease modifying drugs
Integrative structural biology of pathological tau protein, an appealing therapeutic target for Alzheimer´s disease modifying drugs
| Duration: | 1. 6. 2022 - 30. 6. 2025 |
| Evidence number: | 873127 |
| Program: | Horizont 2020 |
| Project leader: | RNDr. Škrabana Rostislav PhD. |
Multi-MeMo - Shorter- and longer-term mechanisms of multimodal interventions to prevent dementia
Krátkodobý a dlhodobý mechanizmus multimodálnej intervencie pre prevenciu demencie
| Duration: | 1. 4. 2023 - 30. 6. 2026 |
| Evidence number: | JPND2022-111 |
| Program: | Horizont Európa |
| Project leader: | MVDr. Mgr. Smolek Tomáš PhD. |
Lipid mediators and glial cells: key candidates for brain homeostasis
Lipid mediators and glial cells: key candidates for brain homeostasis
| Duration: | 1. 6. 2024 - 31. 5. 2027 |
| Evidence number: | CRP/SVK23-01 |
| Program: | ICGEB |
| Project leader: | Mgr. Majerová Petra PhD. |
Neu-Vasc - Neurovascular damage determines disease pathophysiology in pediatric mild traumatic brain injury: source of new biomarkers
Neurovaskulárne poškodenie určuje patofyziológiu ochorenia u detských pacientov po traumatickom poškodení mozgu: zdroj nových biomarkerov
| Duration: | 1. 1. 2020 - 31. 12. 2025 |
| Evidence number: | JTC2019: Neu-Vasc |
| Program: | ERANET |
| Project leader: | doc. RNDr. Filipčík Peter CSc. |
| Annotation: |
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Non-globular proteins in the era of Machine Learning
| Duration: | 1. 10. 2022 - 31. 10. 2026 |
| Evidence number: | CA21160 |
| Program: | COST |
| Project leader: | Ing. Cehlár Ondrej PhD. |
PROGRESS - Disease-predisposing or resilience-promoting? Decoding the systems biology and behavioural predictors and determinants of the tipping point of stress
Predisponujúce k chorobám alebo podporujúce odolnosť? Dekódovanie biológie systémov, markerov a determinantov bodu zlomu stresu
| Duration: | 1. 12. 2023 - 30. 11. 2026 |
| Evidence number: | NEURON II/2023/77 |
| Program: | ERANET |
| Project leader: | prof. Ing. Jurišica Igor DrSc. |
premodiALS - A premotor disease signature for ALS
Rukopis pre-motorického štádia amytrofnej laterálnej sklerózy
| Duration: | 1. 9. 2022 - 31. 8. 2025 |
| Evidence number: | JPND2021-650-122 |
| Program: | Horizont 2020 |
| Project leader: | doc. MVDr. Žilka Norbert DrSc. |
Antineuropatho - Developing novel nanopharmaceutics against bacterial infections at center nervous system
Vývoj nových nanoliečiv proti bakteriálnym infekciám v centrálnom nervovom systéme
| Duration: | 1. 1. 2022 - 31. 12. 2025 |
| Evidence number: | ENM III/2021/165 |
| Program: | ERANET |
| Project leader: | prof. MVDr. Bhide Mangesh Ramesh PhD. |
National Projects
Analysis of Psychoneuroimmunological Parameters of Health in Specific Population Groups in Slovakia
Analýza psychoneuroimunologických parametrov zdravia vo vybraných skupinách slovenskej populácie
| Duration: | 1. 7. 2023 - 30. 6. 2027 |
| Evidence number: | APVV-22-0160 |
| Program: | APVV |
| Project leader: | prof. RNDr. Kontseková Eva DrSc. |
Whole-of-societal Impact of Traumatic Brain Injuries in Slovakia
Celospoločenský dopad úrazov mozgu v Slovenskej Republike
| Duration: | 1. 7. 2023 - 30. 6. 2026 |
| Evidence number: | APVV-22-0613 |
| Program: | APVV |
| Project leader: | RNDr. Čente Martin PhD. |
The double-edged sword of the plasminogen system: From homeostasis maintenance to COVID-19
Dvojsečný meč plazminogénového systému: Od udržiavania homeostázy po COVID-19
| Duration: | 1. 8. 2021 - 30. 6. 2025 |
| Evidence number: | APVV-20-0513 |
| Program: | APVV |
| Project leader: | RNDr. Škrabana Rostislav PhD. |
Identification of novel biomarkers and signaling pathways after traumatic brain injury
Identifikácia nových biomarkerov a signálnych dráh po traumatickom poranení mozgu
| Duration: | 1. 1. 2023 - 31. 12. 2026 |
| Evidence number: | 2/0086/23 |
| Program: | VEGA |
| Project leader: | RNDr. Čente Martin PhD. |
Aggregation prone conformation of protein tau targetable by specific antibodies
K agregácii náchylná konformácia proteínu tau rozpoznateľná špecifickými protilátkami
| Duration: | 1. 1. 2023 - 31. 12. 2026 |
| Evidence number: | 2/0125/23 |
| Program: | VEGA |
| Project leader: | Ing. Cehlár Ondrej PhD. |
Gut-Brain Axis communication during formation of tau neurofibrillary pathology in Alzheimer's disease: Is the immune system mediator of this process?
Komunikačná os medzi mozgom a črevom v priebehu tvorby tau neurofibrilárnej patológie u Alzheimerovej choroby: Môže byť imunitný systém mediátorom tohto procesu?
| Duration: | 1. 9. 2024 - 30. 6. 2027 |
| Evidence number: | APVV-23-0420 |
| Program: | APVV |
| Project leader: | MVDr. Mgr. Smolek Tomáš PhD. |
Lipids as a tool to control neurodegeneration and neuroinflammation
Lipidy a ich úloha v modulácii neurodegenerácie a neurozápalu
| Duration: | 1. 1. 2024 - 31. 12. 2026 |
| Evidence number: | 2/0075/24 |
| Program: | VEGA |
| Project leader: | Mgr. Majerová Petra PhD. |
Longitudinal monitoring of adaptive immunity after SARS-CoV -2 infection and vaccination: markers of imunity
Longitudinálne monitorovanie adaptívnej imunity po infekcii SARS-CoV-2 a očkovaní: markery imunity
| Duration: | 1. 7. 2022 - 30. 6. 2025 |
| Evidence number: | APVV-21-0478 |
| Program: | APVV |
| Project leader: | prof. RNDr. Kontseková Eva DrSc. |
Small ordered motifs in regulation of pathophysiology of disordered protein tau
Malé štruktúrované motívy ako regulátory patofyziológie prirodzene neusporiadaného tau proteínu
| Duration: | 1. 7. 2022 - 30. 6. 2025 |
| Evidence number: | APVV-21-0479 |
| Program: | APVV |
| Project leader: | RNDr. Škrabana Rostislav PhD. |
Management of Brain Injury Risks in Contact Sport Players - Diagnosis and Prevention of Neurodegeneration
Manažment rizík poranenia mozgu u hráčov kontaktných športov – diagnostika a prevencia neurodegenerácie
| Duration: | 1. 7. 2023 - 30. 6. 2026 |
| Evidence number: | APVV-22-0470 |
| Program: | APVV |
| Project leader: | doc. RNDr. Filipčík Peter CSc. |
Mitochondrial transplantation, an inovative strategy for the therapy of Alzheimer's disease
Mitochondriálna transplantácia, inovatívna stratégia terapie Alzheimerovej choroby
| Duration: | 1. 7. 2024 - 30. 6. 2027 |
| Evidence number: | APVV-23-0368 |
| Program: | APVV |
| Project leader: | doc. MVDr. Žilka Norbert DrSc. |
Neuro-glia cell-based model for inter-neuronal spread of tau pathology
Neuro-gliový multi-bunkový model pre šírenie tau patológie
| Duration: | 1. 7. 2021 - 30. 6. 2025 |
| Evidence number: | APVV-20-0585 |
| Program: | APVV |
| Project leader: | RNDr. Žilková Monika PhD. |
Novel insights into Tauopathy mechanism: lipids as a tool to control neurodegeneration and neuroinflammation
Nový pohľad na mechanizmus tauopatií: lipidy ako nástroj na kontrolu procesu neurodegenerácie a neurozápalu
| Duration: | 1. 9. 2024 - 31. 8. 2025 |
| Evidence number: | 09I03-03-V06-00019 |
| Program: | Plán obnovy EÚ |
| Project leader: | Mgr. Majerová Petra PhD. |
Novel insights into Tauopathy mechanism: lipids as a tool to control neurodegeneration and neuroinflammation
Nový pohľad na mechanizmus tauopatií: lipidy ako nástroj na kontrolu procesu neurodegenerácie a neurozápalu
| Duration: | 1. 7. 2023 - 30. 6. 2026 |
| Evidence number: | APVV-22-0313 |
| Program: | APVV |
| Project leader: | Mgr. Majerová Petra PhD. |
Novel receptor-mediated delivery system for brain therapeutics
Nový receptorom sprostredkovaný systém pre transport liečiv do mozgu
| Duration: | 1. 7. 2022 - 30. 6. 2025 |
| Evidence number: | APVV-21-0254 |
| Program: | APVV |
| Project leader: | Ing. Hanes Jozef DrSc. |
Preaggregation and oligomeric conformation of disordered protein tau
Pre-agregačná a oligomérna konformácia neusporiadaného proteínu tau
| Duration: | 1. 9. 2024 - 30. 6. 2026 |
| Evidence number: | 09I03-03-V04-00623 |
| Program: | Plán obnovy EÚ |
| Project leader: | Ing. Cehlár Ondrej PhD. |
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Štipendiá pre excelentných výskumníkov ohrozených vojnovým konfliktom na Ukrajine
| Duration: | 15. 3. 2023 - 14. 3. 2026 |
| Evidence number: | 09I03-03-V01-00147 |
| Program: | Iné projekty |
| Project leader: | doc. Hryntsová Natalia Borisovna PhD. |
Mechanism of tau protein movement through and out of the brain
Štúdium mechanizmu pohybu tau proteínu v CNS
| Duration: | 1. 7. 2022 - 30. 6. 2025 |
| Evidence number: | APVV-21-0321 |
| Program: | APVV |
| Project leader: | PharmDr. Kováč Andrej PhD. |
Translational research for diagnosis and treatment of heatstroke
Translačný výskum v oblasti diagnostiky a liečby úpalu
| Duration: | 1. 7. 2024 - 30. 6. 2026 |
| Evidence number: | 09I03-03-V03-00086 |
| Program: | Plán obnovy EÚ |
| Project leader: | PharmDr. Kováč Andrej PhD. |
Examining the role of dopamine and adult neurogenesis in learned behavior of songbirds using optogenetic manipulation
Určenie úlohy dopamínu a neurogenézy v dospelosti pre naučené správanie spevavcov pomocou optogenetickej manipulácie
| Duration: | 1. 7. 2021 - 30. 6. 2025 |
| Evidence number: | APVV-20-0344 |
| Program: | APVV |
| Project leader: | MUDr. Mgr. Hromádka Tomáš PhD. |
Validation and characterization of interaction partners of the tau protein – an important player in several neurodegenerative diseases
Validácia a charakterizácia interakčných partnerov tau proteínu – významného hráča viacerých neurodegeneratívnych ochorení
| Duration: | 1. 1. 2024 - 31. 12. 2026 |
| Evidence number: | 2/0146/24 |
| Program: | VEGA |
| Project leader: | Mgr. Šinský Jakub PhD. |
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Vplyv celkovej anestézie na dynamiku zmien markerov mozgového poškodenia pri operáciách kraniosynostóz v dojčenskom veku
| Duration: | 1. 1. 2023 - 31. 12. 2026 |
| Evidence number: | 1/ 0564/23 |
| Program: | VEGA |
| Project leader: | MUDr. Parrák Vojtech |
The impact of perineuronal nets and diffuse extracellular matrix on the propagation of tau pathology in Alzheimer´s disease
Vplyv perineuronálnych sietí a difúznej extracelulárnej matrix na šírenie tau patológie pri Alzheimerovej chorobe
| Duration: | 1. 7. 2024 - 30. 6. 2027 |
| Evidence number: | APVV-23-0436 |
| Program: | APVV |
| Project leader: | prof. MUDr. Syková Eva DrSc. |
Specific structure of tau protein filaments as triggers of diagnostic peripheral biomarkers for diagnostic of chronic traumatic encephalopathy and other tauopathies
Vplyv špecifickej štruktúry filamentov tau proteínu na indukciu periférnych biomarkerov pre diagnostiku chronickej traumatickej encefalopátie a ďalších tauopátií
| Duration: | 1. 1. 2023 - 31. 12. 2026 |
| Evidence number: | 2/0141/23 |
| Program: | VEGA |
| Project leader: | RNDr. Škrabana Rostislav PhD. |
Use of extracellular vesicular biomarkers for patients’ selection for clinical trial on non-pharmacological approaches in patients suffering from dementia
Využitie extracelulárnych vezikulárnych biomarkerov pre výber pacientov do klinickej štúdie zameranej na testovanie nefarmakologických prístupov u pacientov s demenciou
| Duration: | 1. 6. 2024 - 31. 5. 2026 |
| Evidence number: | 09I01-03-V04-00039 |
| Program: | Plán obnovy EÚ |
| Project leader: | Mgr. Kováčech Branislav PhD. |
Development of modern analytical strategies for complex characterization of immunogenic protein keyhole limpet hemocyanin
Vývoj moderných analytických prístupov pre komplexnú charakterizáciu imunogénneho proteínu KLH
| Duration: | 1. 9. 2024 - 30. 6. 2026 |
| Evidence number: | 09I03-03-V04-00622 |
| Program: | Plán obnovy EÚ |
| Project leader: | doc. PharmDr. Piešťanský Juraj PhD. |
Projects total: 37