Centre of Biosciences SAS
Smart deep brain simulation as (SDBS) as a treatment strategy in brain disorders
Name of the supervisor
MMedSc Eliyahu Dremencov, DrSc
Faculty of Natural Sciences, Comenius University in Bratislava
Impaired connectivity between different brain areas is involved in pathophysiology of multiple brain disorders. For example, unproper functioning of the cortex-habenula-ventral pallidum axis might be involved in mania and depression. Smart deep brain simulation (SDBS), combining real- time detection of the neuronal activity in one brain area (e.g., cortex) with the stimulation of another brain area (e.g., ventral pallidum), might be thus an effective treatment for these disorders. PhD student involved in this project will examine neurophysiological, neurochemical, and behavioral effects of SDBS in laboratory animals.