Institute of Neuroimmunology
Topic
Molecular basis of the interaction of tau proteins with heparan sulphate proteoglycans
PhD. program
Immunology
Year of admission
2024
Name of the supervisor
Ing. Ondrej Cehlár, PhD.
Contact:
Receiving school
The University of Veterinary Medicine and Pharmacy in Košice
Annotation
One way of entry of tau proteins into the cells during the propagation of tau pathology is their interaction with surface heparan sulphate proteoglycans (HSPG). The molecular basis of the interaction can be studied using structural biology, cell biology methods and using the computational methods of molecular dynamics and molecular docking.