Biomedical Research Center SAS
Diabetic cardiomyopathy – impact of obesity and diabetes in female Zucker-diabetic fatty rats
Name of the supervisor
RNDr. Michal Cagalinec, PhD.
Faculty of Natural Sciences, Comenius University in Bratislava
The aim of the work is to characterize cardiac myocyte calcium dynamics and ultrastructure in Zucker-diabetic fatty female rats and compare these characteristics in lean and obese variants with/out developed cardiomyopathy to distinguish pathomechanisms induced by diet, obesity and dibetic condition.