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PhD. Topics

Biomedical Research Center SAS

Activation of endogenous mechanisms leading to neuroprotection after stroke
PhD. program
zoology and animal physiology
Name of the supervisor
RNDr. Petra Bonová, PhD.
Receiving school
Faculty of Science, Pavol Jozef Šafárik University in Košice
Stroke represents a serious socio-economic problem with limited treatment options. Recently, the phenomenon of ischemic tolerance, i.e. endogenous stimulation of the mechanisms with the ability to induce neuroprotection, has become an attractive solution for the prevention and treatment of such conditions.
1. Study of mechanisms of ischemic tolerance
2. Defining the role of peripheral blood cells in inducing ischemic tolerance
3. Testing of in vivo and ex vivo conditioning methods
4. Testing of conditioning methods in animal models of ischemic-reperfusion injury of nerve tissue