Preparation of polymeric nanomaterials
Physical chemistry, technology of polymeric materials
Name of the supervisor
Ing. Anita Eckstein, PhD.
Faculty of chemical and food technology STU
Nanotechnologies play an important role in many areas of the specific needs of people. In medicine, for example, nanomaterials are used to improve the diagnosis of diseases and the therapeutic functions of existing chemotherapeutics. Nanomaterials exist at the level of nanometers with unique properties that are not present compared to their larger opposites. Properties such as size, shape, surface chemistry, superparamagnetism, and specific light absorption and emission have enabled their use in a wide variety of biomedical applications. The aim of the dissertation is the preparation and characterization of biocompatible nanoparticles. Chitosan derivatives containing quaternary ammonium and sulfonated groups are used for the preparation of nanoparticles. Chitosan analogs will be studied concerning the ability of the system to form particles, according to the hydrodynamic diameter of the particles, as well as the amount of incorporated drug and its release behavior, which is then characterized by UV-Vis and HPLC.