The list of national projects SAS
Institute of Parasitology
Alternative methods for assessing contamination rates of aquatic ecosystem using fish and their parasites
Alternatívne metódy hodnotenia miery kontaminácie vodného ekosystému s využitím rýb a ich parazitov
| Duration: |
1.1.2020 - 31.12.2023 |
| Program: |
VEGA |
| Project leader: |
RNDr. Oros Mikuláš PhD. |
| Annotation: | Some regions of Eastern Slovakia are known for a high degree of severe polychlorinated biphenyl (PCB)
pollution. PCBs are highly toxic contaminants that persist in the environment for a long time and pose a significant
risk to human and animal health. The highest levels of PCBs, exceeding the ecological and health limits, were
measured in the sediments of the Zemplínska Šírava reservoir, but their further spread by its adjacent rivers is
not known. The aim of the project is a comprehensive research of PCB pollution of Zemplínska Šírava and
adjacent rivers using analytical methods and bioindicators, selected fish species and their parasites. An important
part of the project is the research of structural, cellular and functional abnormalities (chromosomal aberrations
and disorders of gametogenesis) in parasites of the contaminated ecosystem. We expect that our results provide
new information on the ecological status of the studied sites, the physiological condition of fish and the risks to
residents of Zemplín. |
Alternative parasite control of small ruminant
Alternatívne terpaie parazitóz malých prežúvavcov
| Duration: |
1.7.2019 - 30.6.2023 |
| Program: |
SRDA |
| Project leader: |
prof. MVDr. Várady Marián DrSc. |
| Annotation: | Diseases caused by helminths of farm animals are among the most serious infectious diseases. They account for over 55% of all livestock diseases in Europe and cause significant losses in animal production figures. The spread of anthelmintic resistance in livestock parasites has led to the failure of therapy and the need to develop new strategies and recommendations for effective control of the antihelminthic parasite resistance. The project offers an alternative strategies to currently used chemotherapy solutions, namely the concept of herbal nutraceuticals as feed for ruminants with an effect against gastrointestinal parasitoses. |
Biogeography and migratory routes of zoonotic tapeworms Dibothriocephalus latus and D. dendriticus (Cestoda: Diphyllobothriidea)
Biogeografia a migračné trasy zoonóznych pásomníc Dibothriocephalus latus a D. dendriticus (Cestoda: Diphyllobothriidea)
| Duration: |
1.1.2021 - 31.12.2024 |
| Program: |
VEGA |
| Project leader: |
RNDr. Hromadová Ivica DrSc. |
| Annotation: | Tapeworms of the order Diphyllobothriidea are causative agents of parasitic zoonosis, diphyllobothriosis. Out of
50 species of the order, six were confirmed as true parasites of humans. Human can acquire infection by
consumption of fish infected with larval stages called plerocercoids. The only autochthonous diphyllobothriid
species in Europe parasitizing human are Dibothriocephalus latus and Dibothriocephalus dendriticus. They were
selected as model parasites of the project due to their medical importance, zoonotic potential and broad
geographic distribution. The aim of the project is to provide the latest data on distribution of both tapeworms in
Europe using molecular markers and genotyping. Genetic interrelationships and migratory routes of world-wide
populations of D. latus and D. dendriticus will be determined by mitochondrial haplotypes and polymorphic
microsatellite loci. The project will reveal if diphyllobothriosis is native in Europe or is a result of trans-continental
introduction. |
Cestodoses with zoonotic potential in Slovakia – negligible risk or serious threat?
Cestodózy so zoonóznym potenciálom na Slovensku – zanedbateľné riziko alebo závažná hrozba?
| Duration: |
1.1.2020 - 31.12.2023 |
| Program: |
VEGA |
| Project leader: |
MVDr. Antolová Daniela DrSc. |
| Annotation: | Tapeworms of the genus Echinococcus, Hymenolepis and Taenia, important from public health point of view, occur in Slovakia. The most severe diseases, alveolar and cystic echinococcosis, are caused by larval stages of E. multilocularis and E. granulosus. Taenia saginata and T. solium infections are less frequent and less pathogenic, but T. solium can cause life-threatening neurocysticercosis. Human hymenolepiasis also occurs rarely, but high prevalence of Hymenolepis nana recorded in small rodents from pet shops, together with its zoonotic potential and recently confirmed ability of neoplastic transformation, confirmed that the risk of human health threat is not negligible. The project aims to extend the current knowledge on occurrence and genetic
diversity of Echinococcus spp., Hymenolepis spp. and Taenia spp. and, through the analyses of immunological parameters in patients with different stage of echinococcosis, clarify the changes of immune response in patients
and to find possibilities of its modulation. |
Small mammals as reservoir for zoonotic pathogens in an urbanizing world – epidemiology and genetic diversity.
Drobné cicavce ako rezervoár zoonóznych patogénov v urbanizujúcom sa svete - epidemiológia a genetická diverzita
| Duration: |
1.7.2022 - 30.6.2026 |
| Program: |
SRDA |
| Project leader: |
MVDr. Miterpáková Martina DrSc. |
| Annotation: | The research project is focused on the transmission of zoonotic pathogens of parasitic Capillaria hepatica, Trichinella spp., Toxocara spp., Echinococcus multilocularis, Hymenolepis spp., Toxoplasma gondii) and bacterial (Bartonella spp., Rickettsia spp., Borrelia spp., etc.) origin through their reservoir hosts – rodents and insectivores. The topic is very closely related to the current intensive urbanization, which is significantly connected with natural habitats modification and changes in the wildlife species distribution. In addition, the common environment shared by urbanized animal species with humans and the zoonotic nature of many pathogens pose a serious risk to public health risks. The presented project aims to conduct complex zoological and epidemiological research providing antecedent information on species spectrum of the reservoir hosts and the pathogens transmitted by them in various habitats of the urban and suburban environment; the phylogenetic analyzes of the obtained isolates will be performed, and the degree of potential infection risk from the veterinary and public health point of view will be determined. The added value of the project consists in the high probability of acquiring rare and precious biological material which can be used also for other biological and medical researches. |
Risk assessment of the parasitozoonoses occurrence using multicriteria analysis approaches
Hodnotenie rizika výskytu parazitozoonóz metódami multikriteriálnej analýzy
Ivermectin - antiparasitic therapy in small ruminants, resistance and residues in food
Ivermektín - antiparazitárna terapia u malých prežúvavcov, rezistencia a reziduá v potravinách.
Integrated monitoring and environmental risk assessment of PCBs and mercury contaminants in the Zemplín Region (Slovakia), one of the most ecologically threatened territories in Europe
Komplexný monitoring a hodnotenie environmentálnych rizík výskytu PCB a kontaminantov ortuti v oblasti Zemplína (Slovensko), jedného z najviac ekologicky ohrozených území Európy
| Duration: |
1.7.2019 - 30.6.2023 |
| Program: |
SRDA |
| Project leader: |
RNDr. Oros Mikuláš PhD. |
| Annotation: | Environmental pollution is one of the most serious problems threatening survival and a future development of
human civilization. Among pollutants, polychlorinated biphenyls (PCBs) and highly toxic heavy metals play a key
role, because they accumulate and persist in the aquatic ecosystem including plants, invertebrates and animals
for a long time. Even though they represent a real danger for human health, the actual dispersal and quantity of
these contaminants in the environment are poorly known. Therefore, the proposed project aims to address the
important questions of environmental pollution of the PCB-contaminated Zemplínska Šírava (eastern Slovakia)
water reservoir, one of the worst man-made polluted spots in Europe, and its surroundings including the adjacent
protected landscape of the Bodrog River basin. All major components of the polluted water reservoir and its
surroundings (sediments, soil, fish, fish parasites, soil and plant parasitic nematodes and plants) will be analyzed
for PCB levels and Hg concentration, using a new interdisciplinary approach, which will combine standard
methods of pollutant detection with the use of bioindicators and molecular cytogenetics. It is expected that the
results of this project will help to better understand the impact of environmental pollution on the aquatic life and
suitability of bioindicators, especially fish parasites, in the biomonitoring of contaminants. |
Modulation of imunity by albendazole and the role of selected miRNAs in experimental alveolar echinococcosis.
Modulácia imunity albendazolom a úloha vybraných miRNAs pri experimentálnej alveolárnej echinokokóze
Molecular and phylogeographical studies of causative agents of emerging zoonoses - alveolar and cystic echinococcosis.
Molekulárne a fylogeografické štúdie pôvodcov vynárajúcich sa zoonóz - alveolárnej a cystickej echinokokózy
| Duration: |
1.1.2022 - 31.12.2025 |
| Program: |
VEGA |
| Project leader: |
RNDr. Šnábel Viliam CSc. |
| Annotation: | Alveolar and cystic echinococcoses, caused by Echinococcus multilocularis and Echinococcus granulosus sensu lato cestodes, are of increasing public health concern in Europe. The project is designed to better recognize
patterns of dissemination of E. multilocularis in the Eurasian continent, and the current distribution of species
lines, which often differ in infectivity. In E. granulosus s.l., attention will be paid to track the occurrence of the
virulent E. granulosus sensu stricto in central-eastern Europe that has recently spread northward from the
endemic Mediterranean region. Phylogeographical relationship in Echinococcus canadensis and E. granulosus
s.s. will be evaluated to indicate historical movements and the current dispersion of their variants in the eastern
Europe and Russia. In G1 and G3 genotypes of E. granulosus s.s., biological characteristics will be evaluated to delineate until which extent they correlate with genetic differences and whether they pose a comparable threat to human infection. |
Soil microbiota in natural forest ecosystems: its response to changing biotic and abiotic factors of habitat
Pôdna mikrobiota v prírodných lesných ekosystémoch, jej odozva na meniace sa biotické a abiotické faktory habitátu
| Duration: |
1.7.2020 - 30.6.2024 |
| Program: |
SRDA |
| Project leader: |
Ing. Renčo Marek PhD. |
| Annotation: | Soil microbiota (including microfauna) plays a key role in nutrient cycles and energy flows, regulating the supply of plant-available nutrients from the soil and hence providing essential services to the forest ecosystem. Therefore, the knowledge about the state of soil microbial and nematode community, factors influencing it and consequently ways of its management is a fundamental need not only in plant productivity, soil ecology but in ecology in general. The aim of the proposed project is to analyse and clarify the responses of soil microbiota including nematodes to variation in abiotic and biotic factors of their habitat in natural forest ecosystems at a local scale and to find out whether the responses differ at a regional and global scale. The study will be conducted at localities with different trees species (European beech and Norway spruce) in natural forest ecosystems. The following issues can be considered innovative: (i) a complex evaluation of relationships in the system plant-soil-soil microbiota, (ii) study of relationships between two groups of soil biota (soil microorganisms and nematodes), (iii) synthesis of results and data on soil microorganisms from different sites in Slovakia and abroad, which allows a certain degree of generalisation. Understanding the responses of soil microbiota to variability in vegetation and abiotic factors is vitally important for the suggestions and recommendations regarding soil protection and biodiversity conservation in relation to climate change
|
Direct and indirect impact of invasive plant species on soil micro and mesofauna biodiversity
Priamy a nepriamy vplyv inváznych druhov rastlín na biodiverzitu pôdnej mikro a mezofauny
| Duration: |
1.1.2020 - 31.12.2023 |
| Program: |
VEGA |
| Project leader: |
Ing. Renčo Marek PhD. |
| Annotation: | In our time, due to global market and goods transportation, spread of the invasive plant species (IPs) has limitless opportunities across the globe. Those species are able quickly occupy new areas; create and form completely new types of vegetation. However, their impact on soil organisms has been studied so far very little. The
proposed project focuses on the basic issues about soil and plant ecology with emphasis on species diversity and structure of soil nematode communities, functional diversity of microorganisms, structure of vegetation and their
interactions in natural ecosystems affected by invasion of non-native invasive plant species. Depending on the type of invasive plant project will analyse the impact of invasion on soil organisms, soil properties, and organic
matter supply in soil. We will evaluate soil environment of uninvaded and invaded ecosystems where soil nematodes and microorganisms will be used as indicators. Data from natural habitats will be verified in experimental conditions. |
Pet animals as effective sentinels of pathogens´ circulation with specific emphasis on vector-borne and zoonotic species
Spoločenské zvieratá ako účinný indikátor cirkulácie patogénov so špecifickým dôrazom na vektormi prenášané a zoonózne druhy
| Duration: |
1.1.2021 - 31.12.2024 |
| Program: |
VEGA |
| Project leader: |
MVDr. Miterpáková Martina DrSc. |
| Annotation: | Epidemiology of infectious diseases of dogs and cats is currently undergoing a phase of rapid changes. The increase in pet travel and trade, urbanisation, plus changes in climate and natural environment can alter the range and abundance of vectors and reservoirs of several serious pathogens and will probably influence the present epidemiological situation. Given that 60-80% of infections are zoonotic in nature, dogs and cats may be effective sentinel animals when assessing the infection exposure for the human population. The project primarily focuses on arthropod-borne pathogens (Anaplasma, Borrelia, Babesia,, Hepatozoon, Dirofilaria, Thelazia a.o.) circulating in different types of urban/suburban environments differing in climate, landscape and biodiversity. The outcome of the project will be a comprehensive knowledge of species composition and abundance of ticks, and epidemiologically important arthropod-borne pathogens threatening both pets and human health in highly populated urban environments. |
Microbial and parasitic organisms spread under the influence of global climate, environmental and social changes
Šírenie mikrobiálnych a parazitických organizmov pod vplyvom globálnych klimatických, environmentálnych a spoločenských zmien
Scholarships for excellent researchers threatened by the war conflict in Ukraine
Štipendiá pre excelentných výskumníkov ohrozených vojnovým konfliktom na Ukrajine
Scholarships for excellent researchers threatened by the war conflict in Ukraine
Štipendiá pre excelentných výskumníkov ohrozených vojnovým konfliktom na Ukrajine
Scholarships for excellent researchers threatened by the war conflict in Ukraine
Štipendiá pre excelentných výskumníkov ohrozených vojnovým konfliktom na Ukrajine
Scholarships for excellent researchers threatened by the war conflict in Ukraine
Štipendiá pre excelentných výskumníkov ohrozených vojnovým konfliktom na Ukrajine
The total number of projects: 18
