Biomedical Research Center SAS
Topic
Application of modern methods of confocal microscopy and respirometry to study metabolic cardiac load
PhD. program
biophysics
Year of admission
2025
Name of the supervisor
RNDr. Michal Cagalinec, PhD.
Contact:
Receiving school
Faculty of Sciences, Pavol Jozef Šafárik University in Košice
Annotation
Cardiovascular complications represent the most common cause of morbidity and mortality in the world. For the detailed study of these conditions, modern biophysical methods such as biophotonics, confocal and super-resolution microscopy, or high-performance respirometry are increasingly being used in the context of research of the cell structure and function, its organelles and specific proteins. Therefore, we will use above-mentioned methods to study calcium signaling and mitochondrial metabolism in selected experimental models of metabolic load on the heart.