The list of national projects SAS
Institute of Experimental Physics
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„Matching“ granty ku zdrojom získaným od súkromného sektora v rámci výskumnej spolupráce - ÚEF SAV
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Diskrétna gravitácia, kvantové javy a ich aplikácia na rôzne druhy fyzikálnej reality
Phase coherent physical systems
Fázovo koherentné fyzikálne systémy
Functionalized magnetic nanoparticles for MRI imaging of drug distribution in the lungs in experimental acute respiratory distress syndrome (ARDS)
Funkcionalizované magnetické nanočastice pre MRI zobrazovanie distribúcie liečiva v pľúcach pri experimentálnom syndróme akútnej respiračnej tiesne (ARDS)
| Duration: |
1.1.2023 - 31.12.2026 |
| Program: |
VEGA |
| Project leader: |
Ing. Koneracká Martina CSc. |
| Annotation: | The current project is focused on the synthesis and functionalization of magnetic nanoparticles (MNPs) for MRI
imaging of the drug N-acetylcysteine distribution in the lungs in experimental acute respiratory distress syndrome
(ARDS). The first step will be to prepare a conjugate consisting of MNPs modified with functional groups suitable
for drug conjugation. MNPs functionalization and drug conjugation will be optimized and studied by
physicochemical methods such as UV/Vis and IR spectroscopy, microscopy, calorimetry or magnetic
measurements. In the next phase, the conjugate will be analyzed by MRI and compared with the properties of
commercially available MRI contrast agents. In the third step, the relevant ARDS model will be created, and the
conjugate will be applied to the lungs. Finally, the conjugate will be imaged using optimized MRI techniques to
study the drug distribution in the lungs in ARDS. The output items of the project have a direct application potential
for clinical practice. |
Functional magnetic/dielectric/multiferroic materials based on rare earth and transition metal oxides
Funkčné magnetické/dielektrické/multiferoické materiály založené na vzácnych zeminách a oxidoch tranzitívnych kovov
Graphene encapsulated two-dimensional magnetic materials as a platform for spintronics devices
Grafénom zapúzdrené dvojrozmerné magnetické materiály ako platforma pre spintronické zariadenia
Searching for states with spin-liquid properties in frustrated magnetic systems
Hľadanie stavov s vlastnosťami spinových kvapalín vo frustrovaných magnetických systémoch
| Duration: |
1.1.2025 - 31.12.2028 |
| Program: |
VEGA |
| Project leader: |
RNDr. Jurčišin Marián PhD. |
| Annotation: | The main aim of the present project is the study of the potential existence of states with spin-liquid properties in
frustrated magnetic systems with various geometric structure (kagome, tetrahedral, octahedral, etc.) in the
framework of exactly solvable models of the classical statistical mechanics on the corresponding recursive
lattices. In the framework of the project, the magnetic and thermodynamic properties of such magnetic systems
related to the frustration will also be studied (the existence of ground states with high macroscopic degeneracy,
anomalous properties of the specific heat at low temperatures, etc.). |
Identification of small molecule motifs effective to inhibit amyloid aggregation of conformationally diverse amyloidogenic proteins
Identifikácia štruktúrnych motívov malých molekúl schopných inhibovať amyloidnú agregáciu amyloidogénnych proteínov s rozdielnou konformáciou
| Duration: |
1.1.2025 - 31.12.2028 |
| Program: |
VEGA |
| Project leader: |
doc. RNDr. Gažová Zuzana DrSc. |
| Annotation: | Amyloid-related diseases, including systemic lysozyme amyloidosis, Alzheimer's disease and diabetes melitus, are characterized by the amyloid aggregation of proteins with distinct conformations. This project aims to identify
small molecules capable of reducing the amount of amyloid aggregates of poly/peptides with diverse native conformation. We will focus on both globular proteins (lysozyme and insulin) and intrinsically disordered protein(IDP) (Aß peptides and tau). The project's objectives include assessing the anti-amyloid potential of small
molecules, evaluating their cytotoxicity, and elucidating the relationship between their structural motifs and anti-amyloid effects. Attention will be given to small molecules with key structural motifs identified in our previous
studies (a conjugated system of aromatic rings, a catechol moiety, planarity, and carboxyl groups) and their hybrid complexes. Thus, the project could pave the way for the development of novel therapeutics for amyloid-related diseases. |
Intelligent micromanipulation with flexible tools controlled by laser traps.
Inteligentná mikromanipulácia pomocou pružných nástrojov ovládaných laserovými pascami.
| Duration: |
1.1.2025 - 31.12.2027 |
| Program: |
VEGA |
| Project leader: |
doc. Ing. Tomori Zoltán CSc. |
| Annotation: | A laser beam focused on a transparent particle floating in a fluid can hold it in place or move it in the desired
direction by the force effects of photons. Using the method of two-photon polymerization a microscopic structure
with several spherical transparent parts can be created, each focused by separate laser beam. With intelligent
control of beams, we can achieve micromanipulation with the entire structure.
The project solves problems of intelligent micromanipulation, performing the required tasks autonomously, but
with the possibility of interactive cooperation with an operator. We plan 3 types of microtools and corresponding
algorithms: a) a tool with flexible jaws for transporting cells to a container designed to measure the mutual
transmission of signals between individual cells, b) a tool rotating in a fluid supplied with flexible fibers with the
ability to measure their deformation, c) ball-shaped tool on flexible filament suitable for viscosity measurement. |
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Kapitálový booster pre schémy na podporu výskumu a vývoja (Magneticky modifikované textílie)
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Kapitálový booster pre schémy na podporu výskumu a vývoja (Viaczložkové ligandy ako modulátory cieľov spojených s patogenézou Alzheimerovej choroby)
The Advanced Protein Biotechnology Consortium: A Model for Fostering Economic Growth and Mitigating Brain Drain in Eastern Slovakia
Konzorcium pokročilých proteínových biotechnológií: Model pre podporu ekonomického rastu a zmiernenie úniku mozgov na východnom Slovensku
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Kvantová spinová dynamika nízkorozmerných systémov
Tunable structures in ferromagnetic cholesteric liquid crystals
Laditeľné štruktúry vo feromagnetických cholesterických kvapalných kryštáloch
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Ligandy na báze aminokyselín ako stabilizátory amyloidogénnych proteínov (AMYSTAP)
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Magnetická frustrácia a kvantové oscilácie v kvázi 2D a 3D boridoch
| Duration: |
1.1.2024 - 31.12.2027 |
| Program: |
VEGA |
| Project leader: |
doc. RNDr. Gabáni Slavomír PhD. |
| Annotation: | Borides form a broad class of materials with diverse physical properties. Metallic geometrically frustrated
magnetic tetraborides (REB4), where RE represents an element from the rare earth group, are quasi-2D
frustrated systems with different anisotropy strength and the same crystal lattice. These systems form an ideal
environment for studying the connections between anisotropy and magnetization processes. With the help of the
deviation of the magnetic field from the easy axis of magnetization, it will be possible to observe those
components of inter-spin interactions that do not appear when the field is oriented in the direction of the easy
axis, which will contribute to the development of more accurate theoretical models. By studying quantum
oscillations in SmB6, which is considered to be a representative of strongly correlated topological systems, and in other selected hexaborides, it will be possible to contribute original results to the long-standing debate whether
SmB6 is a topological insulator or not. |
Soft magnetic nanocrystalline materials prepared by unconventional thermal processing techniques
Magneticky mäkké nanokryštalické materiály pripravené nekonvenčnými technikami tepelného spracovania
Magnetically modified textiles
Magneticky modifikovaný textil
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Mezoškálové javy v systémoch polymérnych a nepolymérnych látok a metodológia skúmania
Nano-functionalization of liquids for liquid-immersed transformers
Nano-funkcionalizácia kvapalín pre olejové transformátory
| Duration: |
1.7.2023 - 30.6.2027 |
| Program: |
SRDA |
| Project leader: |
RNDr. Rajňák Michal PhD. |
| Annotation: | The current increase in electricity consumption and the greening of its distribution, together with the increase in the price of materials for the production of distribution transformers, represent a challenge for applied research in electric power engineering. The intention of the presented project is to respond to this challenge by functionalizing the current liquids used in electrical transformers in order to increase their cooling efficiency while maintaining or improving their dielectric and insulating properties. For this project, the liquids used in the distribution transformers of the manufacturer interested in this research will be selected. These are commercial liquids primarily based on liquefied natural gas, synthetic and natural esters. Based on current state of the art, the liquids will be functionalized by means of nanotechnologies and nanomaterials, which can significantly improve thermal conductivity, natural and thermomagnetic convection, and thus make the overall heat transport in the liquids more efficient. The functionalizing nanoadditives will be mainly made from carbon (fullerene, nanodiamond) and iron oxides or other ferromagnetic elements. The functionalized liquids will undergo laboratory measurements of physico-chemical, electrical, magnetic and thermal properties. Based on the analyzes of laboratory experiments and numerical simulations, nanofluids with the greatest potential for improving the thermal and insulating properties of the transformer will be selected. The selected nanofluids will be tested by the industrial partner (the customer of the research results) and applied in the selected distribution transformer. The transformer will be subjected to electrical and temperature rise tests. One can expect that the nanofunctionalization of the liquids will result in a lower operating temperature of the transformer, which can lead to an extension of the transformer service life and to the production of smaller transformers. |
Non-centrosymmetric superconductors
Necentrosymetrické supravodiče
Low-dimensional Superconducting Devices
Nízkorozmerné supravodivé aparáty
| Duration: |
1.9.2024 - 31.12.2027 |
| Program: |
SRDA |
| Project leader: |
Mgr. Szabó Pavol CSc. |
| Annotation: | Ultralow temperatures have become an important tool for new research avenues in nanoscience, materials research and particularly in quantum nanotechnologies. Scaling down a physical system towards the sizes when the quantum properties surpass classical physics opens a plethora of new quantum-driven effects, thus giving rise to new classes of quantum materials. Within the proposed project we will focus our study on low-dimensional quantum devices, heterostrucures consisting of atomically thin superconducting slabs and aditional layers with different order (inslulator, metal, ferromagnet). In such systems symmetries can be broken possibly allowing for non trivial topological quantum states relevant for future technologies. Atomically thin layered materials are systems with zero limit bulk-to-surface ratio. Their physical properties are strongly affected by interfacing with other systems. Therefore, they represent an accessible platform for the abundance of quantum effects that can be engineered by combining them into vertical stacks using exfoliation techniques. One identifies two types of layered systems – atomically thin artificially prepared van der Waals heterostructures [Science 353, aac9439 (2016)], and naturally layered three-dimensional crystal systems. A special class of naturally layered materials is misfit structures combining alternating atomic layers of hexagonal transition metal dichalcogenides and slabs of ionic rare-earth monochalcogenides in the same superlattice [APL Mater 10, 100901 (2022)]. They feature new state of quantum matter, the Ising superconductivity resulting from broken inversion symmetry and strong spin-orbit coupling as has been recently shown by us. The misfits are also exfoliative and thus incorporable as units in vertical stacks. |
Optimised growth and the transport and optical properties of thin layers of selected topological semimetals
Optimalizovaný rast a transportné a optické vlastnosti tenkých vrstiev vybraných topologických polokovov
| Duration: |
1.7.2024 - 30.6.2027 |
| Program: |
SRDA |
| Project leader: |
prof. RNDr. Samuely Peter DrSc., akademik US Slovenska |
| Annotation: | One of the fundamental results of quantum mechanics in the 1920s was the derivation of relativistic equations for massive fermions (Dirac), massless fermions (Weyl) and fermions that are themselves antiparticles (Majorana). Since those times, particle physics has been searching for particles representing Weyl and Majorana's fermions. However, their search has not yet been successful. In the last twenty years, it has been shown that the band structure of some materials has such unique characteristics that the charge carriers in them can behave according to the dynamics satisfying the Dirac or Weyl relativistic equations. Such materials include compounds from the group of transition metals dichalcogenides, which we will focus on in our project. We will work with very thin layers of selected materials from this group, such as PtSe2, MoTe2 and WTe2. The first step in the implementation of the project will be the preparation of such layers by chalcogenisation of thin films of transition metals. Their transport and optical properties will then be thoroughly investigated. Temperature-dependent transport measurements can show us transitions between different structures of the same material. We expect that a metal-insulator transition can be observed when the thickness of such thin films is varied. Some of these materials can go into a superconducting state at very low temperatures. We will also try to induce this state in close proximity, i.e. when the thin layer is in contact with another superconductor. Optical measurements will be correlated with transport measurements. We derive essential frequency-dependent characteristics, such as optical conductivity, from the latter. We will look for characteristics theoretically predicted for Dirac and Weyl fermions in the optical conductivity. |
Impact of magnetic quantum and thermal phase transitions on technological innovations
Prínos magnetických kvantových a teplotných fázových prechodov pre technologické inovácie
| Duration: |
1.9.2025 - 31.8.2029 |
| Program: |
SRDA |
| Project leader: |
RNDr. Vargová Hana PhD. |
| Annotation: | This project aims to explore the fundamental properties and technological potential of thermal and quantum phase
transitions in low-dimensional quantum magnetic systems. To address these highly topical challenges emerging at
the intersection of quantum magnetism and quantum information science, we will employ state-of-the-art analytical
and numerical computational methods including exact mapping transformations, localized-magnon theory, exact
diagonalization, classical and quantum Monte Carlo simulations, density-matrix renormalization group method,
tensor-network techniques, etc. A primary focus will be on optimizing the cooling efficiency of magnetocaloric
cycles near phase transitions of 2D quantum magnets, which could contribute to the development of energy-saving
cooling technologies crucial for quantum computers based on superconducting qubits. Additionally, we will
investigate the stability and phase transitions of skyrmion phases in frustrated triangular antiferromagnets with
possible implications for spintronic applications. Another key objective is to study topologically nontrivial quantum
states, particularly cluster-based Haldane states and bound magnons in frustrated quantum spin systems, which
may provide promising platforms for quantum computing, quantum information storage and processing.
Furthermore, we will also explore the optimization of quantum heat engines based on magnetic spin systems assessing their efficiency for energy conversion and quantum batteries. Another specific task of the project is the
study of quantum entanglement and quantum phase transitions in fractal lattices with the aim to uncover the impact
of complex lattice geometries on quantum correlations and critical phenomena. |
Processing and performance of critical-elements-free hard and soft magnetic materials for sustainable development
Príprava a vlastnosti magneticky tvrdých a mäkkých materiálov bez kritických prvkov pre trvalo udržateľný rozvoj
Programmable self-organization of hybrid DNA-protein nanosystems for controlled binding and release of biologicals
Programovateľné samo-usporiadanie hybridných DNA-proteín nanosystémov pre kontrolovateľné viazanie a uvoľnovanie biologicky aktívnych látok
| Duration: |
1.7.2024 - 30.6.2028 |
| Program: |
SRDA |
| Project leader: |
RNDr., Ing. Šipošová Katarína PhD. |
| Annotation: | Protein self-assembly is a process based on autonomous, non-covalent interactions between distinct building blocks without requirement of external energy sources. The possibility of chemical appending of functional ligands onto self-assembling peptides or proteins lays the foundation for developing new materials with unprecedented structural and functional features. Especially using sequence addressable DNAs, the synergistic combination into DNA-protein self-assembling systems, may lead to unique and sophisticated functional hybrid nanostructures, which are highly programmable and display remarkable features that create new opportunities to build materials on the nanoscale. Inspired by the unique ability of proteins to self-assemble into amyloid fibrils, we plan to use recombinant spider silk eADF4(C16) protein, insulin, Aβ peptide and lysozyme in order to demonstrate the versatility of the concept of DNA-assisted self-organization of higher-order fibrillar structures. We will explore two dynamic association modes, the temperature-controlled hybridization event of short overlapping DNA sequences and the highly specific DNA-aptamer-to-ligand binding controlled by the ligand affinity. Generally, we foresee the feasibility of the proposed nanofibrillar systems mate of DNA-protein hybrids for the construction of nanostructured materials in biomedical research for binding and release of biologically active agents, formation of multiple protein arrangements for efficient enzymatic cascades or even dyes positioning for efficient light harvesting systems. |
Progressive magnetic emulsions
Progresívne magnetické emulzie
| Duration: |
1.1.2025 - 31.12.2028 |
| Program: |
VEGA |
| Project leader: |
Ing. Molčan Matúš PhD. |
| Annotation: | Pickering emulsion (PE) is an emulsion stabilized by solid particles accumulated at the surface of droplets. New emulsions with additive properties such as magnetism are emerging. To stabilize PE, ferromagnetic iron oxide particles can be used, with magnetic nanoparticles composing the droplet shells. The magnetic shell of Pickering droplets allows response to magnetic manipulation. Research tasks involve the preparation of magnetic particles (spherical, core-shell, magnetosomes) and their functionalization, studying primary magnetic and structural properties (particle size, surface modification, hydrophobicity/hydrophilicity, and stability). Subsequently, the particles will be used to prepare magnetic PE. A novel approach to emulsion production using ultrasound and electric fields will be employed. The impact of particles on the properties of emulsions will be investigated: magnetic, dielectric, rheological, and ultrasonic. Verifying their heating effect under alternating magnetic fields will also be crucial. |
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Pružné mikroštruktúry a mikroroboty pre biomedicínske labon-chip aplikácie
| Duration: |
1.7.2022 - 30.6.2026 |
| Program: |
SRDA |
| Project leader: |
doc. Ing. Tomori Zoltán CSc. |
| Annotation: | The development boom of biomedical lab-on-chip (LOC) applications during the last two decades brought the need
for the miniaturization of conventional mechanical actuators, sensors, and manipulators. Light-driven mechanical
microstructures, trapped and moved by optical tweezers, can be easily integrated into the microfluidic LOC
environment. The vast majority of light-driven microstructures is prepared by two-photon polymerization. It is the
main objective of the present project to exploit the possibilities of working with flexible (deformable) microstructures, which were not used in biomedical applications, yet. Two well-defined LOC application areas are
targeted: micro-rheology and single-cell manipulation. Micro-viscometers utilizing the effect of the surrounding fluid
medium on the deformation (deflection) of flexible micro-cantilevers will be developed. The novel viscometer
devices will be either anchored to the bottom glass surface or kept mobile and optically transportable inside the
micro-fluidic system. Light-driven elastic micro-robots will be designed and tested for capture, transport, and
release of single live cells. The operation of the developed micro-manipulators will be automated to build
multicellular systems, mimicking the tissue conditions, in an autonomous way. To facilitate the flexible
microstructure development and optimization, the material properties of the photo-polymers will be determined by
comparing experimental deformation data with the results of numerical simulations. |
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REBCO masívne supravodiče na báze Y, Gd, Sm a Eu pre praktické aplikácie
| Duration: |
1.7.2022 - 30.6.2026 |
| Program: |
SRDA |
| Project leader: |
Ing. Diko Pavel DrSc., akademik US Slovenska |
| Annotation: | The project is focused on research and development of selected REBCO bulk singlegrain superconductors (BSS).
We will examine YBCO, GdBCO, SmBCO and EUBCO systems, which are currently preferred in terms of
mastering their production technology and specific applications. Based on our latest results, we will focus on the
alloying of LREBCO (LRE- light rare earths) with elements that suppress Ba/LRE substitution in the crystal lattice,
the addition of nanocrystalline BaCeO3, the bimodal size distribution of pining centres and the configuration of
holes in REBCO BSS. We will apply the research results in the development of BSS production technology with
optimized superconducting and mechanical properties. The use of the research and development results achieved
within the project is expected by the manufacturer BSS CAN Superconductors s.r.o.
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Slovak Technical Ecosphere Platform
Slovenská technická ekosférická platforma
| Duration: |
1.4.2025 - 30.9.2027 |
| Program: |
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| Project leader: |
RNDr. Mackovjak Šimon PhD. |
| Annotation: | STEPHANIK aims to establish a nationally and internationally competitive ecosystem for modular satellite technologies in Slovakia by:
• developing and validating modular satellite building blocks up to TRL 2–4,
• building a network of joint laboratories and cleanroom facilities across partner institutions,
• creating a talent pipeline of highly skilled space engineers, researchers and operators,
• creating conditions for systematic import of international excellence into Slovak space research,
• enabling future flight missions and commercial exploitation by Slovak academic and industrial partners. |
Spin injection into diamond for quantum magnetoelectronics
Spin injection into diamond for quantum magnetoelectronics
Misfolding proteins in amyloid diseases and their prevention/therapy
Štipendiá pre excelentných PhD. študentov a študentky (R1) – UEF SAV
2D magnetism: probing and controlling magnetic states in 2D layered materials
Štipendiá pre excelentných výskumníkov a výskumníčky R2-R4 (2D magnetizmus: skúmanie a riadenie magnetických stavov v 2D vrstvených materiáloch)
| Duration: |
1.9.2024 - 31.8.2026 |
| Program: |
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| Project leader: |
RNDr. Orendáč Matúš PhD. |
| Annotation: | This research project explores the magnetic properties of quasi-2D and 2D layered materials, with a focus on tetraborides and kagome systems. The study aims to uncover the fundamental origins and dynamic behaviors of magnetism in these materials by using experimental investigations and theoretical modeling. Additionally, this research aims to explore the potential applications of these materials in advanced technologies such as recording devices, spintronics, and piezoelectric systems. To achieve these objectives, the project involves mastering the fabrication of novel 2D heterostructures through an innovative stamping technique, enabling precise control over material properties and interfaces. By improving our understanding of 2D materials and their magnetic properties, this research contributes to the fields of frustrated magnetic systems and quantum-2D magnetism. |
Magnetic nanoflowers for biomedical applications
Štipendiá pre excelentných výskumníkov a výskumníčky R2-R4 (Magnetické nanokvety pre biomedicínske aplikácie)
| Duration: |
1.9.2024 - 31.8.2026 |
| Program: |
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| Project leader: |
RNDr. Khmara Iryna PhD. |
| Annotation: | Today, nanoscale materials are of great interest for their potential to be used in a wide range of areas, especially in biomedical applications such as detection, early diagnosis and effective treatment of oncological disease. One of the therapies that are actively being developed is magnetic hyperthermia (MH) as an alternative approach for the local treatment of tumours. MH utilizes the heat generated by the magnetic nanoparticles (MNPs) when are subjected to an alternating magnetic field. Thus, the better MNPs are heated, the lower concentration of MNPs in the cancer tissue is required resulting in reducing the risk of side effects. Therefore, the heating ability and heating rate of these MNPs is extremely important. In this regard, the clustering of MNPs into nanoflowers, novel systems in terms of morphology showing a structure similar to a flower, can improve their heating rate of these MNPs is extremely important. In this regard, the clustering of MNPs into nanoflowers, novel systems in terms of morphology showing a structure similar to a flower, can improve their heating characteristics compared to their building blocks, i.e. monocrystals of MNPs and thus increase the heating efficiency of MH. |
Self-assembled structures in ferromagnetic liquid crystals
Štipendiá pre excelentných výskumníkov a výskumníčky R2-R4 (Samousporiadané štruktúry vo feromagnetických kvapalných kryštáloch)
Exploring discrete gravity, muon magnetic moment anomaly, and the black hole information paradox
Štipendiá pre excelentných výskumníkov a výskumníčky R2-R4 (Skúmanie diskrétnej gravitácie, anomálneho magnetického momentu miónu a informačného paradoxu čiernych dier)
Influence of synthesis parameters on the structure and properties of bulk high-temperature EuBCO-Ag superconductors applied in medical technologies
Štipendiá pre excelentných výskumníkov a výskumníčky R2-R4 (Vplyv parametrov syntézy na štruktúru a vlastnosti masívnych vysokoteplotných EuBCO-Ag supravodičov využiteľných v medicínskych technológiách)
Study of elementary magnetization processes of powder compacted and composite materials.
Štúdium elementárnych magnetizačných procesov v práškových kompaktovaných a kompozitných materiáloch
| Duration: |
1.1.2024 - 31.12.2027 |
| Program: |
VEGA |
| Project leader: |
RNDr. Kováč Jozef CSc. |
| Annotation: | The project is focused on the experimental study of elementary magnetization processes, especially on domain
walls displacements, in powder compacted and composite materials based on 3d transition metals. In this class
of magnetic materials, the influence of individual electrically and magnetically non-insulated or isolated particles
on the magnetization processes of surrounding particles significantly affects their magnetic properties. In the case
of using electro-insulating materials with suitable magnetic materials, the mutual interaction of ferromagnetic
particles can be significantly affected. The magnetization processes are in some cases different than that in usual
materials prepared by conventional casting. Considering the class of materials prepared by compaction of
isolated or non-insulated particles is becoming increasingly important, the knowledge of these peculiarities is
useful in developing 3D materials for practical use in electrotechnology. |
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Štúdium vysokoenergetických kozmických lúčov z vesmíru a ich interakcie s atmosférou Zeme pomocou neutrínových teleskopov
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Teoretické štúdium vlastností geometricky a interakčne frustrovaných magnetických systémov
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Viaczložkové ligandy ako modulátory cieľov spojených s patogenézou Alzheimerovej choroby
Influence of dynamic charge stripes on quantum magnets and superconductors in extreme conditions
Vplyv dynamických nábojových pásov na kvantové magnety a supravodiče v extrémnych podmienkach
| Duration: |
1.7.2024 - 30.6.2028 |
| Program: |
SRDA |
| Project leader: |
doc. RNDr. Gabáni Slavomír PhD. |
| Annotation: | The project is aimed at solving the urgent fundamental problem of the genesis of the so-called of dynamic charge stripes (DCS) - inhomogeneous distribution of conduction electron oscillations - and their influence on the properties of strongly correlated electron systems (SCES). The charge stripes play an important role in the high-temperature superconductivity (HTSC) of cuprates and also underlie the mechanisms responsible for the colossal magnetoresistance in manganites, cobaltites, iron-based HTSCs, etc. Observing directly the effect of DCS on the scattering of charge carriers in the mentioned SCES is very sophisticated due to their complex composition, low symmetry of the crystal structure and high sensitivity to external conditions. Instead, it is suitable to use model SCES. Such model materials are rare earth dodecaborides (RB12) with Jahn-Teller structural instability and electronic phase separation on the nanoscale range, in which the appearance of dynamic charge stripes was reliably determined for the first time both for superconductors (ZrB12, LuB12) and for quantum magnets (R = Ho, Er, Tm). The comprehensive study of DCS will be extended by additional model systems based on hexaborides (RB6) and frustrated quantum magnets based on rare earth tetraborides (RB4), and will includes the influence of external extreme conditions such as very low temperatures, high magnetic fields and pressures. |
Enhancement of superconducting parameters in high-entropy alloy thin films
Vylepšenie supravodivých parametrov vysoko-entropických zliatin tenkých filmov
| Duration: |
1.1.2024 - 31.12.2027 |
| Program: |
VEGA |
| Project leader: |
RNDr. Pristáš Gabriel PhD. |
| Annotation: | Superconducting materials have become an integral part of the latest technologies such as quantum computers,
single-photon detectors, magnetic resonance, SQUID, etc. Achieving room-temperature superconductivity is no
more the only goal, but targeted improvement of superconducting parameters (upper critical field, critical
temperature) for application needs is the key. Extreme conditions in the form of very low temperatures, high
pressures and reduction dimensions into quasi-two dimensions are very powerful tools in this endeavor. In
particular, in case of thin films the superconducting properties can be tuned by several external parameters (e.g.
film thickness, substrate, interfaces). The main goal of the project is to improve superconducting parameters of
the high-entropy alloys and other materials in the form of thin films in purpose for use in future quantum
applications technology. |
Exploitation of natural substances conjugated with magnetic nanocarriers in diagnostics and treatment of colon cancer
Využitie prírodných látok konjugovaných s magnetickými nanonosičmi v diagnostike a liečbe karcinómu hrubého čreva
| Duration: |
1.9.2025 - 31.8.2029 |
| Program: |
SRDA |
| Project leader: |
Ing. Koneracká Martina CSc. |
| Annotation: | Cancer is the second leading cause of death globally, therefore, considerable worldwide research is in progress to develop new drugs, diagnosis and therapy methods for cancer treatment. In this project proposal, we will firstly focus on design and synthesis of a multifunctional magnetic nanoparticle system consisting of a natural biologically active substance conjugated on magnetic nanoparticles (nanobioconjugate) and, secondly, on evaluation of their diagnostic and therapeutic potential for the application in oncology. The first step to achieve the desired goals will be the synthesis of magnetic nanoparticles and the functionalization of their surface with suitable biocompatible materials. Several physicochemical methods will be used to characterize and to optimize the preparation of multifunctional magnetic nanoparticles (magnetic NPs). The key step of the project will be immobilization of natural biologically active substances on magnetic NPs to form nanobioconjugate for cancer targeting and drug delivery. Considering the goal of the project, nanobioconjugate anticancer efficiency will be tested using colorectal carcinoma models in vitro and in vivo, as well. The project is based on a complex multidisciplinary approach, ranging from physics, and chemistry up to biophysics, biochemistry and biomedicine. The involved partners possess key skills, infrastructure and are highly motivated to reach the project goals. |
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Získavanie energie magnetickými kvapalinami
The total number of projects: 45
