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Institute: Institute of Neurobiology

Neuroprotective potential of cryopreserved placental mesenchymal stem cells (MSCs), extract, cord blood serum in the spinal cord injury (SCI).
Neuroprotektívne potenciál zamrazených mezenchýmových kmeňových buniek (MSCs) placenty, extraktov, séra pupočníkovej krvi pri poranení miechy (SCI).
Program: Inter-academic agreement
Project leader: RNDr. Slovinská Lucia PhD.
Annotation:Determine the neuroprotective potential of cryopreserved placental MSC, placental extract and cord blood serum with spinal cord injuries. Determine the neuroprotective potential of cryopreserved placental MSC, placental extract and cord blood serum with spinal cord injuries.
Duration: 1.1.2017 - 31.12.2019

Targeting molecular pathways of glycolipotoxicity by a novel carboxymethylated mercaptotriazinoindole inhibitor of aldo-keto reductase AKR1B1 in diabetes, inflammation and age-related neurodegeneration.
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Program: Bilateral - other
Project leader: RNDr. Račeková Enikö CSc.
Duration: 15.4.2016 - 15.4.2019

Endurance Training and/or administration of neurotrophic factor as a novel therapeutic approach for treatment of Spinal Cord Injury
Vytrvalostný tréning a/alebo aplikácia rastových faktorov ako nové terapeutické prístupy v liečbe miechy po jej poranení
Program: Bilateral - other
Project leader: RNDr. Lukáčová Nadežda DrSc.
Annotation:Neurotrophic factors (NF) are known to mediate the effect of physical activity on neurogenesis and motor function. Our working hypothesis is that endurance training and/or the administration of NF into selected spinal cord regions after spinal cord injury will enhance the level of NF and improve functional recovery after spinal trauma. While the levels of NF and their receptors are spontaneously down regulated at the site of injury, we anticipate that endurance training enhance the expression of NF and their receptors in motoneurons of spinal cord.
Duration: 1.1.2016 - 31.12.2018

Developing of innovative method of spinal cord injury effective treatment.
Vývoj inovatívnej metódy na efektívnu liečbu poškodenia miechy.
Program: Inter-academic agreement
Project leader: RNDr. Gálik Ján CSc.
Duration: 1.1.2017 - 31.12.2019

The total number of projects: 4