Information Page of SAS Organisation

Institute of Neuroimmunology

International projects

JPsustaiND - Coordination Action in support of the sustainability and globalisation of the Joint Programming Initiative on Neurodegenerative Diseases
Coordination Action in support of the sustainability and globalisation of the Joint Programming Initiative on Neurodegenerative Diseases
Program: Horizont 2020
Project leader: prof. MVDr. Novák Michal DrSc., Dr.h.c.
Duration: 1.11.2015 - 1.11.2019

REfrAME - Pathway complexities of protein misfolding in neurodegenerative diseases: a novel approach to risks evaluation and model development
Mechanizmy patologickej transformácie proteínov pri neurodegeneračných ochoreniach: nové prístupy vyhodnotenia rizík a vývoj modelov
Program: Horizont 2020
Project leader: prof. MVDr. Novák Michal DrSc., Dr.h.c.
Duration: 1.5.2016 - 30.4.2019

NGP-NET - Non-globular proteins - from sequence to structure, function and application in molecular physiopathology (NGP-NET)
Ne-globulárne bielkoviny, ich sekvencia, štruktúra, funkcia a zapojenie v molekulárnej normálnej a patologickej fyziológii
Program: COST
Project leader: RNDr. Škrabana Rostislav PhD.
Annotation:Non-globular proteins (NGPs) encompass different molecular phenomena that defy the traditional sequence-structure-function paradigm. NGPs include intrinsically disordered regions, tandem repeats, aggregating domains, low-complexity sequences and transmembrane domains. Although growing evidence suggests that NGPs are central to many human diseases, functional annotation is very limited. It was recently estimated that close to 40 of all residues in the human proteome lack functional annotation and many of these are NGPs. While a better understanding of NGPs is crucial to fully comprehend human molecular physiopathology, progress has been hampered so far by the lack of a systematic approach to their study.This Action Proposal aims to create a pan-European scientific network of groups that work on NGPs to strengthen, focus and coordinate research in this field. It proposes to develop a novel classification of NGPs by consensus among interested experts that will be showcased on a newly developed web site, along with meetings, training schools and scientific missions on NGP-related topics.
Duration: 31.5.2015 - 25.3.2019

AxonRepair - Spinal cord repair: releasing the neuron-intrinsic brake on axon regeneration
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Program: ERANET
Project leader: MVDr. Čižková Dáša DrSc.
Duration: 1.1.2017 - 31.12.2019


National projects

Is it possible to stop the spreading of neurofibrillary degeneration by active stimulation of the brain?
Dokáže aktívna stimulácia mozgu zastaviť šírenie neurofibrilárnej degenerácie?
Program: VEGA
Project leader: Doc. MVDr. Žilka Norbert DrSc.
Duration: 1.1.2016 - 31.12.2018

Immunogenetic markers in Slovak patients with Alzheimer´s disease
Imunogenetické markery u slovenských pacientov s Alzheimerovou chorobou
Program: VEGA
Project leader: MUDr., Mgr. Hromádka Tomáš PhD.
Duration: 1.1.2016 - 31.12.2019

Inhibtion of expression of natively unfolded proteins and its consequence for progression of neurodegeneration
Inhibícia expresie prirodzene nezvinutých proteínov a jej dôsledky pre progresiu neurodegeneratívnych zmien
Program: VEGA
Project leader: doc. RNDr. Filipčík Peter CSc.
Duration: 1.1.2016 - 31.12.2018

The model of the neuroimmune crosstalk in Alzheimer´s disease
MODEL BUNKOVEJ KOMUNIKÁCIE MEDZI NERVOVÝM A IMUNITNÝM SYSTÉMOM V ALZHEIMEROVEJ CHOROBE
Program: APVV
Project leader: Doc. MVDr. Žilka Norbert DrSc.
Duration: 1.7.2015 - 30.6.2018

Molecular profiling of miRNA and gene expression changes in a model of human tauopathy
MOLEKULÁRNY PROFIL MIRNA A ZMENY GÉNOVEJ EXPRESIE V MODELI ĽUDSKÝCH TAUOPATIÍ
Program: VEGA
Project leader: MUDr. Kosoň Peter PhD.
Duration: 1.1.2015 - 31.12.2018

Damage of the blood-brain barrier of transgenic rat models for tauopathies
POŠKODENIE MOZGOVO-CIEVNEJ BARIÉRY V PROSTREDÍ NEURODEGENERÁCIE U TRANSGÉNNYCH POTKANÍCH MODELOV PRE TAUOPÁTIE
Program: VEGA
Project leader: PharmDr. Kováč Andrej PhD.
Duration: 1.1.2015 - 31.12.2017

The aging of the immune system and biomarkers of human immunosenescence
Starnutie imunitného systému a biologické markery imunosenescencie
Program: VEGA
Project leader: Mgr. Vince Kážmérová Zuzana PhD.
Duration: 1.1.2016 - 31.12.2018

Structural study of multiple homologous epitopes present on the molecule of intrinsically disordered protein tau
ŠTRUKTÚRA SEKVENČNE HOMOLÓGNYCH EPITOPOV VIACNÁSOBNE PRÍTOMNÝCH NA MOLEKULE PRIRODZENE NEUSPORIADANÉHO PROTEÍNU TAU
Program: VEGA
Project leader: Ing. Cehlár Ondrej PhD.
Duration: 1.1.2015 - 31.12.2018

Study of functional bio-implants and cell therapy for the CNS regeneration
Štúdium funkčných bio-implantátov a bunkovej terapia pre regeneráciu CNS
Program: APVV
Project leader: MVDr. Čižková Dáša DrSc.
Duration: 1.7.2016 - 30.6.2020

Development of novel peptide based system for delivery of therapeutics into the brain
VÝVOJ NOVÉHO PEPTIDOVÉHO SYSTÉMU PRE TRANSPORT LIEČIV DO MOZGU
Program: APVV
Project leader: PharmDr. Kováč Andrej PhD.
Duration: 1.7.2015 - 30.6.2018

Functional impact of Alzheimer's disease on cortical neurons
Zmeny funkcie kôrových neurónov pri Alzheimerovej chorobe
Program: VEGA
Project leader: MUDr., Mgr. Hromádka Tomáš PhD.
Duration: 1.1.2016 - 31.12.2018

Projects total: 15