Differentiation pathways in carcinogenesis and in chemo- and radioresistance

In: NEOPLASMA, vol. 59, no. 1

M Janikova - J Skarda

Detaily:

Rok, strany: 2012, 6 - 17

O článku:

Cancer stem cells (CSCs) share many features with embryonic stem cells (ESCs) such as the ability for self-renewal and differentiation. Signaling pathways that are involved in these processes are also involved in chemo- and radioresistance (e.g. Wnt, Notch and Hedgehog pathways). This review is focused on the influence of three important differentiation pathways on carcinogenesis and on chemo- and radioresistance in ESCs and CSCs. Keywords: Stem cell, Chemoresistance, Radioresistance, Wnt pathway, Notch pathway, Hedgehog pathway

Ako citovať:

ISO 690:

Janikova, M., Skarda, J. 2012. Differentiation pathways in carcinogenesis and in chemo- and radioresistance. In NEOPLASMA, vol. 59, no.1, pp. 6-17. 0028-2685.

APA:

Janikova, M., Skarda, J. (2012). Differentiation pathways in carcinogenesis and in chemo- and radioresistance. NEOPLASMA, 59(1), 6-17. 0028-2685.