In: NEOPLASMA, vol. 52, no. 4
H. Lalic
Detaily:
Rok, strany: 2005, 307 - 313
O článku:
The intention of the study was to find out whether in spite of
carrying out the required protection measures in using therapeutic
and diagnostic machines there is an increased frequency of
structural chromosome aberrations in medical staff professionally
exposed to ionizing radiation. The other objective was to find out
whether there are consequential differences in
exposure to Gamma and X radiation. The classic genotoxic method of
analyzing chromosome aberrations in peripheral
blood lymphocytes was used. and 200 metaphases per examinee were
analyzed. Twenty-five staff members of Oncology
Department exposed to Gamma radiation were examined by that
method, 22 of Radiology Department exposed to X radiation,
as well as 20 unexposed medical employees. The results have shown
that chromatid breaks (CB) differ significantly in
the three examined groups (p<0.05). The difference is even more
significant in acentric fragments (AC), (p<0.001). In both
the highest values are in the group of Gamma radiation exposure.
Translocational aberrations (DIC) and tetraradiuses (TET)
occured in the group exposed to Gamma radiation, while in other
two groups that was not the case. There was a considerable
positive correlation between the years of exposure to ionizing
radiation and occurrence of acentric fragments. Aberration
analysis per cell showed the highest frequency of structural
aberrations in examinees exposed to Gamma radiation. It seems
that protection measures in Gamma radiation departments are not
always satisfactory. Furthermore, continual monitoring of
Radiology Department staff exposed to X radiation is necessary, as
their aberration frequency is higher than the control, the
unexposed group of examinees.
Ako citovať:
ISO 690:
Lalic, H. 2005. Cytogenetic monitoring of medical staff professionally exposed to
Gamma and X radiation. In NEOPLASMA, vol. 52, no.4, pp. 307-313. 0028-2685.
APA:
Lalic, H. (2005). Cytogenetic monitoring of medical staff professionally exposed to
Gamma and X radiation. NEOPLASMA, 52(4), 307-313. 0028-2685.