In: NEOPLASMA, vol. 52, no. 4
J. Bacovsky - V. Scudla - M. Myslivecek - J. Nekula - M. Vytrasova
Detaily:
Rok, strany: 2005, 302 - 306
O článku:
Technetium-99m methoxyisobutylisonitrile ([99m]Tc-MIBI) has been
shown to be useful in identifying several types of tumors,
such as breast, brain, thyroid gland, malignant lymphomas and
multiple myeloma.
In this study, 102 patients with multiple myeloma (MM) and 32
patients with monoclonal gammopathy of undetermined
significance (MGUS) had been evaluated for correlation between
[99m]Tc-MIBI and biochemical and hematological markers
of activity of the disease. Significant statistical correlation
was found between summary score (SS) of [99m]Tc-MIBI
scintigrams and beta2-microglobulin (p<0.001), monoclonal
immunoglobulin level MIG (p<0.001), serum thymidinekinase
- sTK (p<0.001), CRP (p<0.05) and cross-linked carboxyterminal
telopeptide of type I collagen - ICTP (p<0.05) bone
marrow plasmocytosis-BMPc (p<0.001) and hemoglobin Hb (p<0.001).
All 32 patients with MGUS had physiological activity
of [99m]Tc-MIBI scintigrams.
Technetium-99m methoxyisobutylisonitrile is a useful
indicator of activity of MM and helps in differentiating
between multiple myeloma and monoclonal gammopathy of
undetermined significance.
Ako citovať:
ISO 690:
Bacovsky, J., Scudla, V., Myslivecek, M., Nekula, J., Vytrasova, M. 2005. Scintigraphy using [99m]Tc-MIBI (sestamibi), a sensitive parameter
of activity of multiple myeloma. In NEOPLASMA, vol. 52, no.4, pp. 302-306. 0028-2685.
APA:
Bacovsky, J., Scudla, V., Myslivecek, M., Nekula, J., Vytrasova, M. (2005). Scintigraphy using [99m]Tc-MIBI (sestamibi), a sensitive parameter
of activity of multiple myeloma. NEOPLASMA, 52(4), 302-306. 0028-2685.