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Zoznam medzinárodných projektov SAV

Lock Databáza medzinárodných projektov
Ústav molekulárnej biológie SAV, v. v. i.
Epidemiológia vody/odpadovej vody: Vývoj spoľahlivých molekulárno-biologických detekčných metód pre dohľad nad ohniskami epidémií
Water/Wastewater epidemiology: Development of robust and reliable molecular detection systems for surveillance of disease outbreaks
Program: Bilaterálne - iné
Zodpovedný riešiteľ: Dr. Pangallo Domenico DrSc.
Anotácia:Before being a health emergency, the COVID-19 pandemic should be considered as a problem related to the unsustainable exploitation of the environment. We retain that the monitoring of the environmental microorganisms and viruses can be a suitable solution to face the next pandemics. Early warning systems are necessary to assess the health status of our cities using the samples recovered from sewage, wastewater, and aquatic environments. These systems can be based on reliable and quick molecular approaches that consent to make prompt decisions against the spreading of dangerous outbreaks. In our project, these molecular systems will be targeted to antibiotic-resistant bacteria (ARB), Dengue virus (DENV), and SARS-CoV-2. ARB are already a real threat, and many pandemics that have not made so much clamor in media occur periodically. DENV is another dramatic reality in many countries (including Taiwan) of tropical and subtropical regions, but by climate change and globalization, this threat can readily spread to other world regions. SARS-CoV-2 is new, and unfortunately, no therapy and vaccine are available at the moment. Through the cooperative works, we will develop and optimize several molecular approaches based on qPCR and RT-qPCR techniques. Such PCR assays will reveal and quantify the described pathogens, and they will be coupled with internal amplification controls able to guarantee their efficiency. Our investigation will be completed by the in-depth analysis of viral and microbial communities, including the resistome. This analysis will consent better to understand the viral and bacterial interactions in studied environments. For this purpose, two different high-throughput sequencing platforms, MinION and NovaSeq 6000, will be used.
Doba trvania: 1.1.2021 - 31.12.2023
Trvalo udržateľná regenerácia vody založená na filtrácii keramickými membránami
Sustainable Water Reclamation Based on Ceramic Membrane Filtration
Program: Bilaterálne - iné
Zodpovedný riešiteľ: Dr. Pangallo Domenico DrSc.
Anotácia:Microplastics are a source of concern since they pose threats to aquatic species as well as human being. They not only contribute to accumulation of plastics in the environment, but due to absorption they can also contribute to spreading of micropollutants to the environment. Studies have shown that wastewater treatment plants are responsible for releasing micropollutants to the environment. Therefore, both detection and removal of microplastics from wastewater treatment plants are of paramount importance. Although the primary treatment process is efficient in removing microplastics of larger size, and microplastic fibers, it doesn’t remove small shaped microplastics. To remove very small shaped microplastic fragments, and to have the highest rate of microplastic removal, membrane technology is the best available technology. Organic membranes can be used for this purpose. Nevertheless, they are damaged easily. Ceramic membranes, on the other hand, have many advantages when compared to organic membranes such as higher abrasion resistance, chemical resistance, ability to be used at a very wide pH range (0 to 14), higher resistance to ozone and chloride, allowing the disinfection of water, and higher thermal resistance. In the light of this information, the aim of this project is to develop a robust durable ceramic membrane which will remove microplastics from secondary treated wastewater. To achieve this aim, tubular ceramic membranes with ultra and nanofiltration layers will be synthesized, and secondary treated wastewater will be treated with these membranes at lab and pilot scale for the removal of microplastics. The cyto-toxicity, genotoxicity and oxidative stress of micro/nanoplastics on human cells will be assessed, previously in vitro and then using the water of the wastewater pilot scale plant. In addition, also the antimicrobial properties of the membrane will be assessed, evaluating the microbial communities’ changes before and after the ceramic membrane treatment.
Doba trvania: 1.4.2020 - 31.3.2023

Celkový počet projektov: 2