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Information Page of SAS Organisation

Project

Institute of Experimental Physics

International Projects

LEAPAB - Inhibition of A-beta Peptides Aggregation by Late Embryogenesis Abundant Proteins: A New Approach for Alzheimer’s Disease Treatment

Inhibícia agregácie A-beta peptidov proteínmi vyskytujúcimi sa počas neskorej embryogenézy: nový prístup liečby Alzheimerovej choroby

Duration: 1. 4. 2024 - 31. 12. 2025
Evidence number:APVV-SK-SRB-23-0062
Program: Bilaterálne - iné
Project leader: RNDr. Bednáriková Zuzana PhD.
Annotation:Alzheimer’s disease (AD) is the most common neurodegenerative disorder, sharing unclear pathophysiology and massive social costs. Today, more than 55 million people have been diagnosed with AD, which is forecast to increase more than twice by 2050. AD is tightly associated with the formation of deposits containing amyloid β (Aβ) peptide organized into insoluble amyloid fibrils. Despite numerous contemporary studies focused on reducing Aβ aggregation, a cure for AD has not yet been found. Our project intends to implement the elements of molecular mechanisms underlying the remarkable phenomenon of plant desiccation tolerance and develop a new Aβ anti-aggregation strategy. Late Embryogenesis Abundant proteins (LEAPs) are markedly induced upon desiccation and can stabilize the native structure of proteins and membranes by a mechanism that is not fully understood. The primary project aim is to investigate the structural properties of Ramonda serbica LEAPs and their interactions with Aβ peptides and aggregation. Firstly, we will recombinantly produce LEAPs with the highest potential to inhibit Aβ aggregation. Further, we will analyze LEAPs’ secondary structure under different conditions, focusing on their order-to-disorder transitions. The final aim is to identify Aβ/LEAPs interactions and assess the Aβ anti-aggregation potential of LEAPs in vitro, which will impact the development of new strategies for AD treatment. The collaborating teams involved in this project (Slovak - IEP SAS and Serbian - IMGGE) were selected based on their expertise in protein production, protein structure analysis and amyloid aggregation. The expertise transfer between partner laboratories will be ensured by mutual training of PhD and postdoc researchers involved in the project.

RETROTRAFO - Development of knowledge and technology to implement retrofilling in power ransformers using biodegradable or recycled fluids and fostering circular economy

Development of knowledge and technology to implement retrofilling in power ransformers using biodegradable or recycled fluids and fostering circular economy

Duration: 1. 9. 2024 - 31. 12. 2027
Evidence number:HORIZON-MSCA-2023-SE-01
Program: Horizont 2020
Project leader: doc. RNDr. Kopčanský Peter CSc.

The ALICE experiment at the CERN LHC: Study of the strongly interacting matter under extreme conditions

Experiment ALICE na LHC v CERN: Štúdium silno interagujúcej hmoty v extrémnych podmienkach

Duration: 1. 1. 2022 - 31. 12. 2026
Evidence number:MŠVVaŠ SR 0409/2022
Program: CERN/MŠ
Project leader: RNDr. Králik Ivan CSc.
Annotation:The project is aimed at the study of strongly interacting matter under extreme conditions of the p-p, p-Pb and Pb-Pb collisions at the energies of the LHC collider at CERN. The main program of the ALICE experimemt is the study of the quark-gluon plasma properties.

ATLAS KE - ATLAS experiment at LHC at CERN: deep-inelastic phenomenons and new physics at TEV energies

Experiment ATLAS na LHC v CERN: hlboko-nepružné javy a nová fyzika pri TeV energiách

Duration: 1. 1. 2022 - 31. 12. 2026
Evidence number:MŠVVaŠ SR 0408/2022
Program: CERN/MŠ
Project leader: RNDr. Stríženec Pavol CSc.

Frustrated quantum magnets - impact of uniaxial pressure

Frustrované kvantové magnety - vplyv jednoosového tlaku

Duration: 1. 1. 2024 - 31. 12. 2025
Evidence number:DAAD-SAS-2023-02
Program: Mobility
Project leader: doc. RNDr. Gabáni Slavomír PhD.

Hybrid DNA-functionalized fibrils as nanostructured material for bioanalytical applications

Hybrid DNA-functionalized fibrils as nanostructured material for bioanalytical applications

Duration: 1. 1. 2024 - 31. 12. 2025
Evidence number:DAAD-SAS-2023-01
Program: Mobility
Project leader: RNDr., Ing. Šipošová Katarína PhD.

CHINMULTIHIT - Discovery and Mechanism of Small Molecules from Traditional Chinese Herbs for Multitarget directed Therapy of Neurodegenerative Diseases

Identifikácia malých molekúl z tradičných čínskych bylín na multicieľovú terapiu neurodegenerat ívnych ochorení a objasnenie mechanizmu účinku

Duration: 1. 7. 2024 - 30. 6. 2026
Evidence number:SK-CN-23-0025
Program: Bilaterálne - iné
Project leader: doc. RNDr. Gažová Zuzana DrSc.
Annotation:Protein misfolding neurodegenerative diseases (NDDs), such as Alzheimer's and Parkinson's diseases, result in extensive cellular and neuronal loss within the central nervous system. Despite the distinct manifestations of these disorders, they share several common pathogenic mechanisms. Current pharmacological interventions are ineffective. Moreover, the complexity of NDDs necessitates innovative therapeutic approaches. In this project, the novel "multi-target-directed ligands" (MTDLs) strategy will be employed as it focuses on development of novel compounds modulating multiple factors simultaneously. We will focus on Chinese herbs - Angelica sinensis, Ligusticum chuanxiong, and Cinnamomum cassia. The project aims to explore the anti-aggregation potential of these herbal extracts and their derivatives targeting both Aβ peptide and α -synuclein, showcasing neuroprotective and anti-inflammatory properties to pave the way for the development of novel t herapeutic strategies for NDDs. The project combines the expertise and experience of both research teams in the field of protein misfolding and NDDs pathology, allowing us to acquire complex data with the aid of complementary approaches, leading to the suggestion of possible alternatives of therapy against these devastating diseases. Moreover, this collaborative research partnership will present an excellent opportunity for both teams' young members to learn new techniques in the well-equipped laboratories at East China University and IEP SAS and gain new experience by working in an international scientific environment.

LAMSoftMag - Laser Additive Manufacturing of Soft Ferromagnetic Metallic Glasses/ Composites

Laserová aditívna výroba magneticky mäkkých kovových skiel/kompozitov

Duration: 1. 7. 2024 - 30. 6. 2026
Evidence number:SK-AT-23-0025
Program: Bilaterálne - iné
Project leader: RNDr. Škorvánek Ivan CSc.

SeNaTa - Self-heating magnetic nanoconstructs for theranostic applications

Magnetické nanoštruktúrne materiály schopné samozahrievania pre teranostické aplikácie

Duration: 1. 7. 2023 - 30. 6. 2025
Evidence number:APVV DS-FR-22-0037
Program: Bilaterálne - iné
Project leader: RNDr. Kubovčíková Martina PhD.
Annotation:Cancer is still one of the leading causes of death worldwide, therefore significant research and innovation efforts are still needed to find new materials and methods for better cancer diagnosis and treatment. Magnetic nanoparticles (MNPs) appear to be a very promising material for use in many medical fields, such as in nanosurgery they can be used to kill tumor cells by increasing drug concentration in target cells in combination with hyperthermia as well. The presented project is focused on the development of new nanoconstructs labeled by radionuclide as a potential theranostic agent for radiotherapy and diagnostics. The first step to achieve the desired goal will be the synthesis of nanoconstructs consisting of self-heating magnetic nanoparticles coated with various biocompatible substances, which will exhibit the desired bioactivity as well. The prepared nanoconstructs will be studied by several physicochemical methods, and their stability and suitability for magnetic hyperthermia, i.e. the ability to produce heat in an alternating magnetic field, will be monitored. In the second step, nanoconstructs with the best properties will be radiolabeled with therapeutic 177Lu and diagnostic 99mTh radionuclides to prepare radioactive nanoconstructs for dual therapy and diagnosis. In the next step, in vitro toxicity testing of nanoconstructs labeled with radionuclides will be performed. The prepared magnetic magnetic nanostructured materials labeled with radionuclides will contribute to the improvement of diagnostics and therapy of cancer diseases. The project is based on a complex multidisciplinary approach, from physics, chemistry to biochemistry and biomedicine. The involved partners possess key skills, infrastructure and are highly motivated to achieve the project goals.

QUID-REGIS - Quiet Ionospheric Disturbances - REsearch based on Ground-based mesospheric and Ionospheric data with Swarm data

Narušenia pokojnej ionosféry - Výskum založený na pozemných meraniach mezosféry a ionosféry a na dátach z ESA misie SWARM

Duration: 1. 2. 2024 - 31. 12. 2026
Program: European Space Agency (ESA)
Project leader: RNDr. Mackovjak Šimon PhD.

ML4NGP - Non-globular proteins in the era of Machine Learning

Neglobulárne proteíny v ére strojového učenia

Duration: 25. 10. 2022 - 26. 10. 2026
Evidence number:COST Action CA21160
Program: COST
Project leader: RNDr. Bednáriková Zuzana PhD.
Annotation:The ML4NGP Action aims to establish an interdisciplinary pan-European network to favour interplay between experiments and computation, fostering experimental frameworks designed to provide information to computational methods, and novel computational methods developed, trained and benchmarked with experimental data. ML4NGP will enhance the primary experimental data generation (WG1), promote integrative structural biology approaches (WG2), benchmark the state-of-the-art ML methods (WG3) and improve the functional characterization of NGPs (WG4). The Action will support its scientific objectives through policies that sustain free knowledge exchange, inclusiveness and training of young researchers who will lead future innovations in this field.
Project web page:https://www.cost.eu/actions/CA21160/

skQCI - skQCI

skQCI

Duration: 1. 1. 2023 - 30. 6. 2025
Evidence number: 10109154
Program: Digital Europe Programme
Project leader: RNDr. Skyba Peter DrSc.
Project web page:https://skqci.qute.sk/sk/slovencina/

SUPERQUMAP - SUPERCONDUCTING NANODEVICES AND QUANTUM MATERIALS FOR COHERENT MANIPULATION

Supravodivé nanozariadenia a kvantové materiály pre koherentnú manipuláciu

Duration: 6. 10. 2022 - 5. 10. 2026
Evidence number:COST CA211444
Program: COST
Project leader: prof. RNDr. Samuely Peter DrSc., akademik US Slovenska
Annotation:We propose a collaborative approach joining together efforts and groups all over Europe, structured around three pathways, (i) the synthesis and characterization of quantum materials with novel topological properties, (ii) the fabrication of sensors and devices exploiting novel superconducting functionalities and (iii) the generation and coherent manipulation of superconducting states that can create new opportunities in the superconducting quantum electronics. Using an open and inclusive approach that joins expertise and capabilities all over Europe, this project will structure collaborative efforts aiming at disruptive achievements in the field of superconductivity. The results will impact far beyond the development of new quantum solutions for computation, and include sectors such as health and energy.

Vigil-ML - Study toward enhancing reliability and timeliness of Vigil mission predictions through Machine Learning

Štúdia smerujúca k zvýšeniu spoľahlivosti a včasnosti predikcií z dát misie Vigil pomocou strojového učenia

Duration: 1. 10. 2023 - 31. 12. 2025
Program: European Space Agency (ESA)
Project leader: RNDr. Mackovjak Šimon PhD.

Hyp4Amy - Ultrasound- and Magnetic-induced Hyperthermia as a Treatment Modality for Amyloid-related Diseases

Ultrazvukom a magneticky indukovaná hypertermia ako liečebná modalita pre amyloidné ochorenia

Duration: 1. 1. 2024 - 31. 12. 2025
Evidence number:SK-PL-23-0058
Program: Bilaterálne - iné
Project leader: RNDr., Ing. Šipošová Katarína PhD.
Annotation:Nanoparticles (NPs), including those with magnetic properties, have attracted significant scientific interest due to their applications in various fields of science and medicine. As a consequence, several promising treatment procedures have been developed, such as controlled and local drug delivery and release, photo- and sonodynamic therapy, and thermal therapy. NPs can also be used as biosensors or imaging contrast agents. Additionally, they are being studied for their potential role in amyloidogenic diseases. Although great efforts have been made to understand the pathogenesis of these diseases and design effective therapy, there is still no treatment for amyloid - related diseases. A possible alternative non-pharmacological option for targeting cross - using energy generated by magnetic NPs as a result of applied magnetic field and/or ultrasound to disrupt large amyloid structures (plaques) into smaller fragments. This proposal is aimed at basic as well as applied research that will help perfect the application of magnetic NPs in the treatment of amyloid-related diseases via thermal and ultrasound-induced processes and enable tomography imaging of amyloid formation/decomposition. Efficacious drug/NPs deposition in the target site and operated activation of therapeutic and imaging agents reduce treatment time, while avoiding adverse damage and side effects resulting from systemic administration. The collaboration will not only promote the bilateral exchange of knowledge, technology and experience, but also may accelerate the translation between biophysical/biochemical science and clinical study.

RBS - Research on bulk superconductors

Výskum masívnych supravodičov

Duration: 1. 5. 2018 - 31. 12. 2026
Evidence number:1/2018
Program: Iné
Project leader: Ing. Diko Pavel DrSc., akademik US Slovenska
Annotation:The agreement on cooperation between IEP SAS and CAN Superconductorsis focused on research od REBCO bulk supercondyctors for practical applications.
Project web page:https://websrv.saske.sk/uef/oddelenia-a-laboratoria/laboratorium-materialovej-fyziky/

SCSS-Net - Development of SCSS-Net: Solar Corona Structures Segmentation algorithm by deep neural networks

Vývoj SCSS-Net: Algoritmus na segmentovanie štruktúr slnečnej koróny pomocou hlbokých neurónových sieti

Duration: 1. 2. 2024 - 31. 12. 2025
Program: European Space Agency (ESA)
Project leader: RNDr. Mackovjak Šimon PhD.

NOMAGRAD - Design of novel materials-based high performance magnetic gradiometer

Vývoj vysoko-citlivého magnetického gradiometra na báze nových magnetických materiálov

Duration: 1. 4. 2024 - 31. 3. 2027
Program: JRP
Project leader: RNDr. Škorvánek Ivan CSc.

PURPLEGAIN - Fundamentals and applications of purple bacteria biotechnology for resource recovery from waste

Základy a aplikácie purpurových baktérií v biotechnológií pre obnovu znečistených zdrojov

Duration: 10. 10. 2022 - 9. 10. 2026
Evidence number:COST Action CA21146
Program: COST
Project leader: RNDr. Pudlák Michal CSc.
Annotation:PURPLEGAIN aims to create a European network to share information, facilitating technology and knowledge transfer between the academic and industrial sectors, related to PPB applications for resource recovery from organic waste sources. Resource recovery includes wastewater or organic waste, open or closed environments, in single or chain processes. The network associates fundamental-focused and applied-research groups, improving lab-scale technology optimization through mechanistic modeling. It benefits the technology transfer from applied-research groups to industry, considerably improving process design.
Project web page:https://www.cost.eu/actions/CA21146/ https://purplegain.eu/

NexMPI - Magnetic Particle Imaging for next-generation theranostics and medical research

Zobrazovanie magnetických častíc pre teranostiku novej generácie a medicínsky výskum

Duration: 22. 10. 2024 - 21. 10. 2028
Evidence number:COST action CA23132
Program: COST
Project leader: RNDr. Kubovčíková Martina PhD.

National Projects

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„Matching“ granty ku zdrojom získaným od súkromného sektora v rámci výskumnej spolupráce  - ÚEF SAV

Duration: 1. 10. 2024 - 31. 3. 2026
Evidence number:09I02-03-V02-00003
Program: Plán obnovy EÚ
Project leader: RNDr. Škorvánek Ivan CSc.

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CURAsoft - kontinuálne rýchle žíhanie pre vývoj nových magneticky mäkkých zliatin s nanokryštalickou štruktúrou

Duration: 1. 1. 2024 - 31. 12. 2025
Evidence number:APD0066
Program: PostdokGrant
Project leader: Ing. Kunca Branislav PhD.

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Dekoherencia v mechanických rezonátoroch pri nízkych teplotách

Duration: 1. 1. 2022 - 31. 12. 2025
Evidence number:VEGA 2/0093/22
Program: VEGA
Project leader: RNDr. Človečko Marcel PhD.

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Diskrétna gravitácia, kvantové javy a ich aplikácia na rôzne druhy fyzikálnej reality

Duration: 1. 1. 2023 - 31. 12. 2026
Program: VEGA
Project leader: RNDr. Pinčák Richard PhD.

HERO - -

Elektrokatalyzátory pre efektívnu produkciu vodíka pre budúce elektrolyzéry a palivové články

Duration: 1. 7. 2021 - 30. 6. 2025
Evidence number:APVV 20-0299
Program: APVV
Project leader: RNDr. Baťková Marianna PhD.
Annotation:The development of activities in the field of hydrogen technologies was also supported by the European Commission in the strategic document "Hydrogen Strategy for a Climate Neutral Europe". Today, Slovakia has suggested own national hydrogen strategy. Already in 2015, the National Hydrogen Association has founded to support research, implementation and use of hydrogen technologies. The Hydrogen Technology Center is being established in Košice with the main "Power-to-Gas" concept using renewable power energy sources with no negative impact on human life and without dependence on fossil fuels. A significant source of hydrogen is water and the electrolysis of water is the most promising technology for hydrogen production. However, before it can be recognized as an economically significant resource for large scale application with an exceptional energy potential, the simple, efficient, and secure methods of hydrogen retrieval have to be developed. For the time being, the most efficient electrocatalysts in terms of overpotential for hydrogen evolution reaction (HER) are noble metals. Unfortunately the high cost and scarcity of noble metals motivate the scientists to find the rival low-cost alternatives. Intrinsic structures of TMP meet the criteria of outstanding electrocatalysts that could further improve their HER performance in membrane electrode assembly. Excellent dispersity of electrocatalysts allows full use of active sites on catalysts to participate in electrode reaction to improve the electrocatalytic efficiency. Therefore, the main challenge in this project is to reduce the production cost of HER and at the same time to maintain the high efficiency of polymer electrode water electrolysis. Substantial aim of the project will be devoted to improve the PEM water electrolysis components mainly electrode materials based on modified carbon fibers electrocatalysts result in the technology which should be more approached to commercial markets.

Functionalized magnetic nanoparticles for MRI imaging of drug distribution in the lungs in experimental acute respiratory distress syndrome (ARDS)

Funkcionalizované magnetické nanočastice pre MRI zobrazovanie distribúcie liečiva v pľúcach pri experimentálnom syndróme akútnej respiračnej tiesne (ARDS)

Duration: 1. 1. 2023 - 31. 12. 2026
Evidence number:VEGA 2/0049/23
Program: VEGA
Project leader: Ing. Koneracká Martina CSc.
Annotation:The current project is focused on the synthesis and functionalization of magnetic nanoparticles (MNPs) for MRI imaging of the drug N-acetylcysteine distribution in the lungs in experimental acute respiratory distress syndrome (ARDS). The first step will be to prepare a conjugate consisting of MNPs modified with functional groups suitable for drug conjugation. MNPs functionalization and drug conjugation will be optimized and studied by physicochemical methods such as UV/Vis and IR spectroscopy, microscopy, calorimetry or magnetic measurements. In the next phase, the conjugate will be analyzed by MRI and compared with the properties of commercially available MRI contrast agents. In the third step, the relevant ARDS model will be created, and the conjugate will be applied to the lungs. Finally, the conjugate will be imaged using optimized MRI techniques to study the drug distribution in the lungs in ARDS. The output items of the project have a direct application potential for clinical practice.

Functional nano- and microwires with outstanding properties

Funkčné nano- a mikrodrôty s význačnými vlastnosťami.

Duration: 1. 1. 2023 - 31. 12. 2025
Evidence number:1/0180/23
Program: VEGA
Project leader: RNDr. Kováč Jozef CSc.
Annotation:The project is focused on the development and characterization of functional nano and microwires, which are characterized by distinctive features physical properties in the form of shape memory phenomenon, magnetocaloric phenomenon, magnetic bistability, etc. These properties can be used with advantages in the construction of miniature sensors and actuators for temperature, elongation etc. Scalable methods will be used to produce these materials (electrodeposition, Taylor Ulitovski method), which enable the preparation of a large number of samples and thus an easy transition to applications. The goal is to examine the most important parameters determining the functional properties, which enables the following phenomena modify from the point of view of working scope and amplitude. The shape of the wire brings shape to the mentioned phenomena anisotropy, which can highlight the functional properties in the selected direction and facilitates the subsequent application of the listed materials.

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Iónové kvapaliny a hlboko eutektické zmesi ako modulátory stability a agregácie proteínov

Duration: 1. 1. 2022 - 31. 12. 2025
Evidence number:VEGA 2/0164/22
Program: VEGA
Project leader: RNDr. Fedunová Diana PhD.

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Kapitálový booster pre schémy na podporu výskumu a vývoja (Magneticky modifikované textílie)

Duration: 1. 7. 2024 - 30. 6. 2025
Evidence number:09I03-03-V06-0050
Program: Plán obnovy EÚ
Project leader: doc. RNDr. Kopčanský Peter CSc.

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Kapitálový booster pre schémy na podporu výskumu a vývoja (Nano-funkcionalizácia kvapalín pre olejové transformátory)

Duration: 1. 7. 2024 - 30. 6. 2025
Evidence number:09I03-03-V06-00049
Program: Plán obnovy EÚ
Project leader: RNDr. Rajňák Michal PhD.

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Kapitálový booster pre schémy na podporu výskumu a vývoja (Viaczložkové ligandy ako modulátory cieľov spojených s patogenézou Alzheimerovej choroby)

Duration: 1. 7. 2024 - 30. 6. 2025
Evidence number:9I03-03-V06-00084
Program: Plán obnovy EÚ
Project leader: doc. RNDr. Gažová Zuzana DrSc.

Tunable structures in ferromagnetic cholesteric liquid crystals

Laditeľné štruktúry vo feromagnetických cholesterických kvapalných kryštáloch

Duration: 1. 1. 2024 - 31. 12. 2027
Evidence number:2/0061/24
Program: VEGA
Project leader: RNDr. Lacková Veronika PhD.

Low-molecular-weight compounds targeting amyloid-related diseases

Low-molecular-weight compounds targeting amyloid-related diseases

Duration: 1. 1. 2024 - 31. 12. 2025
Evidence number:APD0046
Program: PostdokGrant
Project leader: RNDr. Gančár Miroslav PhD.

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Magnetická frustrácia a kvantové oscilácie v kvázi 2D a 3D boridoch

Duration: 1. 1. 2024 - 31. 12. 2027
Evidence number:2/0034/24
Program: VEGA
Project leader: RNDr. Orendáč Matúš PhD.
Annotation:Borides form a broad class of materials with diverse physical properties. Metallic geometrically frustrated magnetic tetraborides (REB4), where RE represents an element from the rare earth group, are quasi-2D frustrated systems with different anisotropy strength and the same crystal lattice. These systems form an ideal environment for studying the connections between anisotropy and magnetization processes. With the help of the deviation of the magnetic field from the easy axis of magnetization, it will be possible to observe those components of inter-spin interactions that do not appear when the field is oriented in the direction of the easy axis, which will contribute to the development of more accurate theoretical models. By studying quantum oscillations in SmB6, which is considered to be a representative of strongly correlated topological systems, and in other selected hexaborides, it will be possible to contribute original results to the long-standing debate whether SmB6 is a topological insulator or not.

Soft magnetic nanocrystalline materials prepared by unconventional thermal processing techniques

Magneticky mäkké nanokryštalické materiály pripravené nekonvenčnými technikami tepelného spracovania

Duration: 1. 1. 2023 - 31. 12. 2026
Evidence number:2/0148/23
Program: VEGA
Project leader: RNDr. Škorvánek Ivan CSc.

MAMOTEX - Magnetically modified textiles

Magneticky modifikovaný textil

Duration: 1. 7. 2023 - 30. 6. 2027
Evidence number:APVV-22-0060
Program: APVV
Project leader: doc. RNDr. Kopčanský Peter CSc.

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Mezoškálové javy v systémoch polymérnych a nepolymérnych látok a metodológia skúmania

Duration: 1. 1. 2023 - 31. 12. 2026
Evidence number:VEGA 2/0071/23
Program: VEGA
Project leader: RNDr. Sedlák Marián DrSc.

NANOFLIT - Nano-functionalization of liquids for liquid-immersed transformers

Nano-funkcionalizácia kvapalín pre olejové transformátory

Duration: 1. 7. 2023 - 30. 6. 2027
Evidence number:APVV-22-0115
Program: APVV
Project leader: RNDr. Rajňák Michal PhD.
Annotation:The current increase in electricity consumption and the greening of its distribution, together with the increase in the price of materials for the production of distribution transformers, represent a challenge for applied research in electric power engineering. The intention of the presented project is to respond to this challenge by functionalizing the current liquids used in electrical transformers in order to increase their cooling efficiency while maintaining or improving their dielectric and insulating properties. For this project, the liquids used in the distribution transformers of the manufacturer interested in this research will be selected. These are commercial liquids primarily based on liquefied natural gas, synthetic and natural esters. Based on current state of the art, the liquids will be functionalized by means of nanotechnologies and nanomaterials, which can significantly improve thermal conductivity, natural and thermomagnetic convection, and thus make the overall heat transport in the liquids more efficient. The functionalizing nanoadditives will be mainly made from carbon (fullerene, nanodiamond) and iron oxides or other ferromagnetic elements. The functionalized liquids will undergo laboratory measurements of physico-chemical, electrical, magnetic and thermal properties. Based on the analyzes of laboratory experiments and numerical simulations, nanofluids with the greatest potential for improving the thermal and insulating properties of the transformer will be selected. The selected nanofluids will be tested by the industrial partner (the customer of the research results) and applied in the selected distribution transformer. The transformer will be subjected to electrical and temperature rise tests. One can expect that the nanofunctionalization of the liquids will result in a lower operating temperature of the transformer, which can lead to an extension of the transformer service life and to the production of smaller transformers.

Iron oxide nanoflowers for magnetic resonance imaging and hyperthermia

Nanokvety na báze oxidov železa pre magnetickú rezonanciu a hypertermiu

Duration: 1. 1. 2024 - 31. 12. 2025
Evidence number:APD0005
Program: PostdokGrant
Project leader: RNDr. Khmara Iryna PhD.

Non-centrosymmetric superconductors

Necentrosymetrické supravodiče

Duration: 1. 1. 2024 - 31. 12. 2027
Evidence number:2/0073/24
Program: VEGA
Project leader: RNDr. Kačmarčík Jozef PhD.

LSD - Low-dimensional Superconducting Devices

Nízkorozmerné supravodivé aparáty

Duration: 1. 9. 2024 - 31. 12. 2027
Evidence number:APVV-23-0624
Program: APVV
Project leader: Mgr. Szabó Pavol CSc.
Annotation:Ultralow temperatures have become an important tool for new research avenues in nanoscience, materials research and particularly in quantum nanotechnologies. Scaling down a physical system towards the sizes when the quantum properties surpass classical physics opens a plethora of new quantum-driven effects, thus giving rise to new classes of quantum materials. Within the proposed project we will focus our study on low-dimensional quantum devices, heterostrucures consisting of atomically thin superconducting slabs and aditional layers with different order (inslulator, metal, ferromagnet). In such systems symmetries can be broken possibly allowing for non trivial topological quantum states relevant for future technologies. Atomically thin layered materials are systems with zero limit bulk-to-surface ratio. Their physical properties are strongly affected by interfacing with other systems. Therefore, they represent an accessible platform for the abundance of quantum effects that can be engineered by combining them into vertical stacks using exfoliation techniques. One identifies two types of layered systems – atomically thin artificially prepared van der Waals heterostructures [Science 353, aac9439 (2016)], and naturally layered three-dimensional crystal systems. A special class of naturally layered materials is misfit structures combining alternating atomic layers of hexagonal transition metal dichalcogenides and slabs of ionic rare-earth monochalcogenides in the same superlattice [APL Mater 10, 100901 (2022)]. They feature new state of quantum matter, the Ising superconductivity resulting from broken inversion symmetry and strong spin-orbit coupling as has been recently shown by us. The misfits are also exfoliative and thus incorporable as units in vertical stacks.

ROTOLES - Optimised growth and the transport and optical properties of thin layers of selected topological semimetals

Optimalizovaný rast a transportné a optické vlastnosti tenkých vrstiev vybraných topologických polokovov

Duration: 1. 7. 2024 - 30. 6. 2027
Evidence number:APVV-23-0564
Program: APVV
Project leader: prof. RNDr. Samuely Peter DrSc., akademik US Slovenska
Annotation:One of the fundamental results of quantum mechanics in the 1920s was the derivation of relativistic equations for massive fermions (Dirac), massless fermions (Weyl) and fermions that are themselves antiparticles (Majorana). Since those times, particle physics has been searching for particles representing Weyl and Majorana's fermions. However, their search has not yet been successful. In the last twenty years, it has been shown that the band structure of some materials has such unique characteristics that the charge carriers in them can behave according to the dynamics satisfying the Dirac or Weyl relativistic equations. Such materials include compounds from the group of transition metals dichalcogenides, which we will focus on in our project. We will work with very thin layers of selected materials from this group, such as PtSe2, MoTe2 and WTe2. The first step in the implementation of the project will be the preparation of such layers by chalcogenisation of thin films of transition metals. Their transport and optical properties will then be thoroughly investigated. Temperature-dependent transport measurements can show us transitions between different structures of the same material. We expect that a metal-insulator transition can be observed when the thickness of such thin films is varied. Some of these materials can go into a superconducting state at very low temperatures. We will also try to induce this state in close proximity, i.e. when the thin layer is in contact with another superconductor. Optical measurements will be correlated with transport measurements. We derive essential frequency-dependent characteristics, such as optical conductivity, from the latter. We will look for characteristics theoretically predicted for Dirac and Weyl fermions in the optical conductivity.

PRESPEED - Perspective electronic spin systems for future quantum technologies

Perspektívne elektrónové spinové systémy pre budúce kvantové technológie

Duration: 1. 7. 2021 - 30. 6. 2025
Evidence number:APVV-20-0150
Program: APVV
Project leader: RNDr. Vargová Hana PhD.
Annotation:The project is aimed at a comprehensive understanding of possibilities and limiting factors of electron spin systems for a quantum computation and quantum information processing, which will be investigated by the combination of advanced analytical and numerical methods including among others exact mapping transformations, localized-magnon theory, exact diagonalization, tensor-network methods, density functional theory, Monte Carlo simulations and density-matrix renormalization group method. In particular, we will examine the possibility to stabilize a bipartite and multipartite entanglement as a genuine quantum phenomenon needed for a quantum computation and quantum information processing at least up to temperature of liquid nitrogen or preferably room temperature. We will also explore the capability of the pulsed electron spin resonance for the spin-qubit manipulation. Quantum spin systems with topologically protected edge states eligible for a topological quantum computation will be investigated in detail together with a few selected quantum spin chains studied in connection with the implementation of a quantum teleportation. Frustrated Heisenberg spin systems supporting either the presence of a nontrivial skyrmion phase or magnon-crystal phases will be investigated in connection with the possibility to store a quantum information or to implement more complex quantum circuits. Heterostructures composed of atomically thin layers coupled by van der Waals forces will be examined with respect to a superconducting pairing and topological quantum computation. The studied electron spin systems will be either motivated by the effort to understand unconventional behavior of existing real magnetic materials or will be supplemented by the respective proposals for their experimental realization.

SUSTAIN - Processing and performance of critical-elements-free hard and soft magnetic materials for sustainable development

Príprava a vlastnosti magneticky tvrdých a mäkkých materiálov bez kritických prvkov pre trvalo udržateľný rozvoj

Duration: 1. 7. 2024 - 31. 12. 2027
Evidence number:APVV-23-0281
Program: APVV
Project leader: RNDr. Škorvánek Ivan CSc.

Heavy quark production as a probe of Quantum Chromodynamics

Produkcia ťažkých kvarkov ako sonda kvantovej chromodynamiky

Duration: 1. 1. 2022 - 31. 12. 2025
Evidence number:VEGA 2/0020/22
Program: VEGA
Project leader: doc. RNDr. Nemčík Ján CSc.
Annotation:The present project is focused on further development and testing of theoretical descriptions of various phenomena inherent in quantum chromodynamics (QCD) in close connections to recent phenomenological models of particle physics. The main emphasize is devoted to investigation of several fundamental aspects of QCD dynamics in production of heavy quarks, mainly in diffractive quarkonium electroproduction on proton and nuclear targets at large energies highly relevant for ongoing measurements at the Large Hadron Collider and with the preparation of physics program for newly approved Electron-Ion Collider.

SelfNano - Programmable self-organization of hybrid DNA-protein nanosystems for controlled binding and release of biologicals

Programovateľné samo-usporiadanie hybridných DNA-proteín nanosystémov pre kontrolovateľné viazanie a uvoľnovanie biologicky aktívnych látok

Duration: 1. 7. 2024 - 30. 6. 2028
Evidence number:APVV-23-0013
Program: APVV
Project leader: RNDr., Ing. Šipošová Katarína PhD.
Annotation:Protein self-assembly is a process based on autonomous, non-covalent interactions between distinct building blocks without requirement of external energy sources. The possibility of chemical appending of functional ligands onto self-assembling peptides or proteins lays the foundation for developing new materials with unprecedented structural and functional features. Especially using sequence addressable DNAs, the synergistic combination into DNA-protein self-assembling systems, may lead to unique and sophisticated functional hybrid nanostructures, which are highly programmable and display remarkable features that create new opportunities to build materials on the nanoscale. Inspired by the unique ability of proteins to self-assemble into amyloid fibrils, we plan to use recombinant spider silk eADF4(C16) protein, insulin, Aβ peptide and lysozyme in order to demonstrate the versatility of the concept of DNA-assisted self-organization of higher-order fibrillar structures. We will explore two dynamic association modes, the temperature-controlled hybridization event of short overlapping DNA sequences and the highly specific DNA-aptamer-to-ligand binding controlled by the ligand affinity. Generally, we foresee the feasibility of the proposed nanofibrillar systems mate of DNA-protein hybrids for the construction of nanostructured materials in biomedical research for binding and release of biologically active agents, formation of multiple protein arrangements for efficient enzymatic cascades or even dyes positioning for efficient light harvesting systems.

MikroFlex - -

Pružné mikroštruktúry a mikroroboty pre biomedicínske labon-chip aplikácie

Duration: 1. 7. 2022 - 30. 6. 2026
Evidence number:APVV-21-0333
Program: APVV
Project leader: doc. Ing. Tomori Zoltán CSc.
Annotation:The development boom of biomedical lab-on-chip (LOC) applications during the last two decades brought the need for the miniaturization of conventional mechanical actuators, sensors, and manipulators. Light-driven mechanical microstructures, trapped and moved by optical tweezers, can be easily integrated into the microfluidic LOC environment. The vast majority of light-driven microstructures is prepared by two-photon polymerization. It is the main objective of the present project to exploit the possibilities of working with flexible (deformable) microstructures, which were not used in biomedical applications, yet. Two well-defined LOC application areas are targeted: micro-rheology and single-cell manipulation. Micro-viscometers utilizing the effect of the surrounding fluid medium on the deformation (deflection) of flexible micro-cantilevers will be developed. The novel viscometer devices will be either anchored to the bottom glass surface or kept mobile and optically transportable inside the micro-fluidic system. Light-driven elastic micro-robots will be designed and tested for capture, transport, and release of single live cells. The operation of the developed micro-manipulators will be automated to build multicellular systems, mimicking the tissue conditions, in an autonomous way. To facilitate the flexible microstructure development and optimization, the material properties of the photo-polymers will be determined by comparing experimental deformation data with the results of numerical simulations.

REBCOAPL - -

REBCO masívne supravodiče na báze Y, Gd, Sm a Eu pre praktické aplikácie

Duration: 1. 7. 2022 - 30. 6. 2026
Evidence number:APVV-21-0387
Program: APVV
Project leader: Ing. Diko Pavel DrSc., akademik US Slovenska
Annotation:The project is focused on research and development of selected REBCO bulk singlegrain superconductors (BSS). We will examine YBCO, GdBCO, SmBCO and EUBCO systems, which are currently preferred in terms of mastering their production technology and specific applications. Based on our latest results, we will focus on the alloying of LREBCO (LRE- light rare earths) with elements that suppress Ba/LRE substitution in the crystal lattice, the addition of nanocrystalline BaCeO3, the bimodal size distribution of pining centres and the configuration of holes in REBCO BSS. We will apply the research results in the development of BSS production technology with optimized superconducting and mechanical properties. The use of the research and development results achieved within the project is expected by the manufacturer BSS CAN Superconductors s.r.o.
Project web page:https://websrv.saske.sk/uef/oddelenia-a-laboratoria/laboratorium-materialovej-fyziky/

skQCI - skQCI

skQCI

Duration: 1. 1. 2023 - 30. 6. 2025
Program: Plán obnovy EÚ
Project leader: RNDr. Skyba Peter DrSc.

R1-Kareem Abdul - Misfolding proteins in amyloid diseases and their prevention/therapy

Štipendiá pre excelentných PhD. študentov a študentky (R1) – UEF SAV

Duration: 1. 9. 2023 - 31. 8. 2027
Evidence number:09I03-03-V02-00039
Program: Plán obnovy EÚ
Project leader: MTech. Kareem Hanan Abdul

2D-MAP - 2D magnetism: probing and controlling magnetic states in 2D layered materials

Štipendiá pre excelentných výskumníkov a výskumníčky R2-R4 (2D magnetizmus: skúmanie a riadenie magnetických stavov v 2D vrstvených materiáloch)

Duration: 1. 9. 2024 - 31. 8. 2026
Evidence number:09I03-03-V04-00304
Program: Plán obnovy EÚ
Project leader: RNDr. Orendáč Matúš PhD.
Annotation:This research project explores the magnetic properties of quasi-2D and 2D layered materials, with a focus on tetraborides and kagome systems. The study aims to uncover the fundamental origins and dynamic behaviors of magnetism in these materials by using experimental investigations and theoretical modeling. Additionally, this research aims to explore the potential applications of these materials in advanced technologies such as recording devices, spintronics, and piezoelectric systems. To achieve these objectives, the project involves mastering the fabrication of novel 2D heterostructures through an innovative stamping technique, enabling precise control over material properties and interfaces. By improving our understanding of 2D materials and their magnetic properties, this research contributes to the fields of frustrated magnetic systems and quantum-2D magnetism.

MagNaFs - Magnetic nanoflowers for biomedical applications

Štipendiá pre excelentných výskumníkov a výskumníčky R2-R4 (Magnetické nanokvety pre biomedicínske aplikácie)

Duration: 1. 9. 2024 - 31. 8. 2026
Evidence number:09I03-03-V04-00296
Program: Plán obnovy EÚ
Project leader: RNDr. Khmara Iryna PhD.
Annotation:Today, nanoscale materials are of great interest for their potential to be used in a wide range of areas, especially in biomedical applications such as detection, early diagnosis and effective treatment of oncological disease. One of the therapies that are actively being developed is magnetic hyperthermia (MH) as an alternative approach for the local treatment of tumours. MH utilizes the heat generated by the magnetic nanoparticles (MNPs) when are subjected to an alternating magnetic field. Thus, the better MNPs are heated, the lower concentration of MNPs in the cancer tissue is required resulting in reducing the risk of side effects. Therefore, the heating ability and heating rate of these MNPs is extremely important. In this regard, the clustering of MNPs into nanoflowers, novel systems in terms of morphology showing a structure similar to a flower, can improve their heating rate of these MNPs is extremely important. In this regard, the clustering of MNPs into nanoflowers, novel systems in terms of morphology showing a structure similar to a flower, can improve their heating characteristics compared to their building blocks, i.e. monocrystals of MNPs and thus increase the heating efficiency of MH.

SASiFER-LC - Self-assembled structures in ferromagnetic liquid crystals

Štipendiá pre excelentných výskumníkov a výskumníčky R2-R4 (Samousporiadané štruktúry vo feromagnetických kvapalných kryštáloch)

Duration: 1. 9. 2024 - 31. 8. 2026
Evidence number:09I03-03-V04-00298
Program: Plán obnovy EÚ
Project leader: RNDr. Lacková Veronika PhD.

EXGRAV - Exploring discrete gravity, muon magnetic moment anomaly, and the black hole information paradox

Štipendiá pre excelentných výskumníkov a výskumníčky R2-R4 (Skúmanie diskrétnej gravitácie, anomálneho magnetického momentu miónu a informačného paradoxu čiernych dier)

Duration: 1. 11. 2024 - 31. 8. 2026
Evidence number:09I03-03-V04-00356
Program: Plán obnovy EÚ
Project leader: RNDr. Pinčák Richard PhD.

BEAST - Influence of synthesis parameters on the structure and properties of bulk high-temperature EuBCO-Ag superconductors applied in medical technologies

Štipendiá pre excelentných výskumníkov a výskumníčky R2-R4 (Vplyv parametrov syntézy na štruktúru a vlastnosti masívnych vysokoteplotných EuBCO-Ag supravodičov využiteľných v medicínskych technológiách)

Duration: 1. 9. 2024 - 31. 8. 2026
Evidence number:09I03-03-V04-00303
Program: Plán obnovy EÚ
Project leader: Mgr. Kuchárová Veronika PhD.

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Štipendiá pre excelentných výskumníkov ohrozených vojnovým konfliktom na Ukrajine

Duration: 1. 9. 2022 - 31. 8. 2025
Evidence number:09I03-03-V01-00051
Program: Plán obnovy EÚ
Project leader: doc. Vitushkina Svitlana PhD.

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Štipendiá pre excelentných výskumníkov ohrozených vojnovým konfliktom na Ukrajine

Duration: 1. 1. 2023 - 31. 12. 2025
Evidence number:09I03-03-v01-00052
Program: Plán obnovy EÚ
Project leader: prof. Oganesyan Koryun DrSc.

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Štúdium a modifikácia vlastností pavúčieho proteínu nadprodukovaného v Escherichia coli

Duration: 1. 1. 2022 - 31. 12. 2025
Evidence number:VEGA 2/0034/22
Program: VEGA
Project leader: RNDr., Ing. Šipošová Katarína PhD.

Study of elementary magnetization processes of powder compacted and composite materials.

Štúdium elementárnych magnetizačných procesov v práškových kompaktovaných a kompozitných materiáloch

Duration: 1. 1. 2024 - 31. 12. 2027
Evidence number:VEGA 1/0016/24
Program: VEGA
Project leader: RNDr. Kováč Jozef CSc.
Annotation:The project is focused on the experimental study of elementary magnetization processes, especially on domain walls displacements, in powder compacted and composite materials based on 3d transition metals. In this class of magnetic materials, the influence of individual electrically and magnetically non-insulated or isolated particles on the magnetization processes of surrounding particles significantly affects their magnetic properties. In the case of using electro-insulating materials with suitable magnetic materials, the mutual interaction of ferromagnetic particles can be significantly affected. The magnetization processes are in some cases different than that in usual materials prepared by conventional casting. Considering the class of materials prepared by compaction of isolated or non-insulated particles is becoming increasingly important, the knowledge of these peculiarities is useful in developing 3D materials for practical use in electrotechnology.

Theoretical study of frustrated magnetic systems

Teoretické štúdium frustrovaných magnetických systémov

Duration: 1. 7. 2021 - 30. 6. 2025
Evidence number:APVV-20-0293
Program: APVV
Project leader: RNDr. Jurčišin Marián PhD.

Theoretical study of cooperative phenomena in strongly correlated electron and spin systems

Teoretické štúdium kooperatívnych javov v silne korelovaných elektrónových a spinových systémoch

Duration: 1. 1. 2022 - 31. 12. 2025
Evidence number:VEGA 2/0037/22
Program: VEGA
Project leader: RNDr. Farkašovský Pavol DrSc.
Annotation:The proposed project is devoted to the theoretical study of cooperative phenomena in strongly correlated electron and spin systems. The special attention will be paid to specifying the key mechanisms which lead to formation and stabilization of inhomogeneous charge and spin ordering, superconductivity, itinerant ferromagnetism, ferroelectric and magnetocaloric phenomenon due to the big application potential of these phenomena and their possible coexistence. The study will be performed on comprehensive model, which will take into account all relevant interactions in rare-earth and transition metal compounds, where besides the spin-independent Coulomb interaction in d and f band also the spin dependent (double exchange) interaction between both bands will be included. For a solution of this model we plan to elaborate new numerical methods, which will be subsequently used in combination with standard methods of quantum statistical physics (DMRG and QMC) to study the above mentioned phenomena.

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Teoretické štúdium vlastností geometricky a interakčne frustrovaných magnetických systémov

Duration: 1. 1. 2023 - 31. 12. 2026
Program: VEGA
Project leader: RNDr. Jurčišinová Eva PhD.

TopoSQ2D - Topological superconductivity in quantum two-dimensional devices

Topologická supravodivosť v kvantových dvojrozmerných zaradieniach

Duration: 1. 4. 2022 -
Evidence number:IM-2021-42
Program: IMPULZ
Project leader: RNDr. Gmitra Martin PhD.
Annotation:The project aims to explore quantum physics in van der Waals 2D materials focusing on discovery of emergent quantum phenomena induced by the spin-orbit coupling and its interplay with magnetism, topology and superconductivity. For this purpose we establish a new Quantum Materials research laboratory with tightly merged theoretical expertise in spin-orbit coupling and experimental expertise in superconductivity. Research will be focused on investigating electronic properties of the prepared heterostructures in normal and superconducting phases using scanning tunneling microscopy and magnetotransport measurements. The theory will be intended for calculation of electronic structure from first-principles and quasiparticle interference spectra and transport properties in order to interpret experimental results and guide further experiments. The studied systems will be further recast towards proof-of-principle devices utilizing topological aspects of superconductivity relevant for quantum computations.

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Viaczložkové ligandy ako modulátory cieľov spojených s patogenézou Alzheimerovej choroby

Duration: 1. 7. 2023 - 30. 6. 2027
Program: APVV
Project leader: doc. RNDr. Gažová Zuzana DrSc.

STRIPEX - Influence of dynamic charge stripes on quantum magnets and superconductors in extreme conditions

Vplyv dynamických nábojových pásov na kvantové magnety a supravodiče v extrémnych podmienkach

Duration: 1. 7. 2024 - 30. 6. 2028
Evidence number:APVV-23-0226
Program: APVV
Project leader: doc. RNDr. Gabáni Slavomír PhD.
Annotation:The project is aimed at solving the urgent fundamental problem of the genesis of the so-called of dynamic charge stripes (DCS) - inhomogeneous distribution of conduction electron oscillations - and their influence on the properties of strongly correlated electron systems (SCES). The charge stripes play an important role in the high-temperature superconductivity (HTSC) of cuprates and also underlie the mechanisms responsible for the colossal magnetoresistance in manganites, cobaltites, iron-based HTSCs, etc. Observing directly the effect of DCS on the scattering of charge carriers in the mentioned SCES is very sophisticated due to their complex composition, low symmetry of the crystal structure and high sensitivity to external conditions. Instead, it is suitable to use model SCES. Such model materials are rare earth dodecaborides (RB12) with Jahn-Teller structural instability and electronic phase separation on the nanoscale range, in which the appearance of dynamic charge stripes was reliably determined for the first time both for superconductors (ZrB12, LuB12) and for quantum magnets (R = Ho, Er, Tm). The comprehensive study of DCS will be extended by additional model systems based on hexaborides (RB6) and frustrated quantum magnets based on rare earth tetraborides (RB4), and will includes the influence of external extreme conditions such as very low temperatures, high magnetic fields and pressures.

Enhancement of superconducting parameters in high-entropy alloy thin films

Vylepšenie supravodivých parametrov vysoko-entropických zliatin tenkých filmov

Duration: 1. 1. 2024 - 31. 12. 2027
Evidence number:2/0091/24
Program: VEGA
Project leader: RNDr. Pristáš Gabriel PhD.
Annotation:Superconducting materials have become an integral part of the latest technologies such as quantum computers, single-photon detectors, magnetic resonance, SQUID, etc. Achieving room-temperature superconductivity is no more the only goal, but targeted improvement of superconducting parameters (upper critical field, critical temperature) for application needs is the key. Extreme conditions in the form of very low temperatures, high pressures and reduction dimensions into quasi-two dimensions are very powerful tools in this endeavor. In particular, in case of thin films the superconducting properties can be tuned by several external parameters (e.g. film thickness, substrate, interfaces). The main goal of the project is to improve superconducting parameters of the high-entropy alloys and other materials in the form of thin films in purpose for use in future quantum applications technology.

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Získavanie energie magnetickými kvapalinami

Duration: 1. 1. 2024 - 31. 12. 2027
Evidence number:VEGA 2/0029/24
Program: VEGA
Project leader: RNDr. Rajňák Michal PhD.

Projects total: 67