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The effects of nitronium ion on nitration, carbonylation and coagulation of human fibrinogen

In: General Physiology and Biophysics, vol. 27, no. 1
M. Ponczek - P. Nowak - B. Wachowicz
Detaily:
Rok, strany: 2008, 55 - 58
O článku:
The effect of nitronium ion on nitration, carbonylation and coagulation of human fibrinogen (Fg) in vitro was investigated. We observed that nitration of tyrosine, induced by NO2BF4 (0.01 mmol/l), was increased. No changes in carbonylation by NO2BF4 (0.01 mmol/l) were noticed. Mentioned alterations were associated with amplified coagulation of Fg. Higher concentrations of NO2BF4 (1 and 0.1 mmol/l) triggered growth of nitration and carbonylation of Fg, but led to inhibi-tion of polymerization. Slight nitration may be responsible for increase, whereas sizable nitration and oxidation may lead to inhibition of Fg coagulation.
Ako citovať:
ISO 690:
Ponczek, M., Nowak, P., Wachowicz, B. 2008. The effects of nitronium ion on nitration, carbonylation and coagulation of human fibrinogen. In General Physiology and Biophysics, vol. 27, no.1, pp. 55-58. 0231-5882.

APA:
Ponczek, M., Nowak, P., Wachowicz, B. (2008). The effects of nitronium ion on nitration, carbonylation and coagulation of human fibrinogen. General Physiology and Biophysics, 27(1), 55-58. 0231-5882.