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Increased ubiquinone concentration after intracerebroventricularly-administered ubiquinol to selected rat brain regions

In: General Physiology and Biophysics, vol. 31, no. 4
Anna Gvozdjáková - Boris Mravec - Jarmila Kucharská - Lubica Lackovičová - Katarína Ondičová - Martin Tkačov - Ram Singh
Detaily:
Rok, strany: 2012, 469 - 472
O článku:
Brain coenzyme Q10 (CoQ10) concentration can influence the activity of several brain regions, including those which participate in the regulation of cardiovascular circadian rhythms, food intake, neuroendocrine stress response, activity and sleep regulation. However, the effect of supplemented ubiquinol (reduced CoQ) into brain regions is not known. This study determined baseline levels of ubiquinone (oxidized CoQ) in various rat brain regions and proved the bioavailability of the liposomal ubiquinol to selected brain regions after its administration into right brain ventricle. Our data indicate that administration of ubiquinol may create the basis for modulation of neuronal activities in specific brain regions.
Ako citovať:
ISO 690:
Gvozdjáková, A., Mravec, B., Kucharská, J., Lackovičová, L., Ondičová, K., Tkačov, M., Singh, R. 2012. Increased ubiquinone concentration after intracerebroventricularly-administered ubiquinol to selected rat brain regions. In General Physiology and Biophysics, vol. 31, no.4, pp. 469-472. 0231-5882.

APA:
Gvozdjáková, A., Mravec, B., Kucharská, J., Lackovičová, L., Ondičová, K., Tkačov, M., Singh, R. (2012). Increased ubiquinone concentration after intracerebroventricularly-administered ubiquinol to selected rat brain regions. General Physiology and Biophysics, 31(4), 469-472. 0231-5882.