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Brain-derived neurotrophic factor blood levels in two models of transient brain ischemia in rats

In: General Physiology and Biophysics, vol. 32, no. 1
Miroslav Gottlieb - Petra Bonova - Viera Danielisova - Miroslava Nemethova - Jozef Burda - Dasa Cizkova
Detaily:
Rok, strany: 2013, 139 - 142
O článku:
We monitored possible influence of transient focal and global brain ischemia on BDNF blood level. In both models noticeable fluctuation of BDNF concentration mainly in reperfusion was observed. During the first 90 min, BDNF in total blood and in blood cells continuously decreased in both models but plasma BDNF raised at 40 min and peaked at 90 min of reperfusion. Our data confirm the impact of transient brain ischemia on BDNF levels in the circulatory system, suggest blood cells as a possible source of BDNF and demonstrate the interdependence of blood compartments and physiological state of an affected organism.
Ako citovať:
ISO 690:
Gottlieb, M., Bonova, P., Danielisova, V., Nemethova, M., Burda , J., Cizkova, D. 2013. Brain-derived neurotrophic factor blood levels in two models of transient brain ischemia in rats. In General Physiology and Biophysics, vol. 32, no.1, pp. 139-142. 0231-5882.

APA:
Gottlieb, M., Bonova, P., Danielisova, V., Nemethova, M., Burda , J., Cizkova, D. (2013). Brain-derived neurotrophic factor blood levels in two models of transient brain ischemia in rats. General Physiology and Biophysics, 32(1), 139-142. 0231-5882.