The list of national projects SAS
Centre for Advanced Materials Application SAS
Carbon-silicon based composite anodes for Li-ion batteries.
Anódy pre Li-iónové batérie na báze uhlík-kremíkových kompozitov
Zero-excess solid-state lithium batteries
Bezanódové tuholátkové lítiové batérie
| Duration: |
1.7.2023 - 31.12.2026 |
| Program: |
SRDA |
| Project leader: |
Dr. rer. nat. Šiffalovič Peter DrSc. |
| Annotation: | The central hypothesis of ZERO project is that by real -time
monitoring of Li deposition rate, wetting and/or alloying, and mechanical stress at the SSE/CC interface, we can
optimize and tailor SSBs providing higher capacity and cycling lifetime. This can be achieved by controlling
charge/discharge currents, appropriate alloy-forming interlayers, and managing internal stresses by external loads.
The main aim of ZERO project is to develop optimal alloy-forming interlayers and charging strategies to achieve the high capacity and cycling lifetime of ZESSBs. This will be enabled and connected with the developing and/or
updating methodologies that will facilitate experimental monitoring and a better conceptual understanding of the
growth phenomena involved in the formation of the Li anode in ZESSBs. To this end, we will develop novel
laboratory and synchrotron techniques to explore ZESSB-related phenomena under in operando conditions. |
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Návrh a optimalizácia biokonjugačných stratégii inovatívnych 2D fototermálnych nanomateriálov s tumor-navádzajúcimi peptidmi
Low energy synthesis of high performance NaSICON-like structured cathodes for rechargeable Sodium-Ion Batteries (SIBs)
Nízko-energetická syntéza katód so štruktúrou NaSICON-u pre nabíjateľné sodíkovo-iónové batérie
| Duration: |
1.1.2021 - 31.12.2024 |
| Program: |
VEGA |
| Project leader: |
Ing. Taveri Gianmarco PhD. |
| Annotation: | This project aims at the development of new synthesis routes for the production of NaSICON materials involving low energy consumption, while still improving its overall electrochemical properties for new generation battery cathodes. The achievement of the project goals relies on the synthesis of new NaSICON precursors at ambient temperature and NaSICON powders at reduced calcination temperature starting from selected low-cost raw materials. Composites synthesis and atomic-layered coatings will be attempted to increase ionic and electrical conductivity and ensuring long-term cyclic life. Spectroscopic techniques will be instrumental in determining the nature and purity of the produced calcined microstructure, while the performance of the sintered components will be assessed through electrochemical testing. The development of the ideas behind this project will provide new interesting methodologies for future production of high-performance NaSICON components at a lower cost than the existing technologies. |
Perovskite-based Films with Superior Passivation and Structure
Perovskitové vrstvy s vylepšenou pasiváciou a štruktúrou
Advanced Oxygen Tolerant Photochemically Induced Atom Transfer Radical Polymerization
Pokročilá fotochemicky indukovaná radikálová polymerizácia s prenosom atómu tolerantná k prítomnosti kyslíka
| Duration: |
1.7.2020 - 30.6.2024 |
| Program: |
SRDA |
| Project leader: |
Mgr. Mosnáček Jaroslav DrSc. |
| Annotation: | Living/controlled polymerizations have a tremendous impact not only on polymer and materials science but also on
related technology. These polymerizations open a wide range of possibilities for the preparation of well-defined
polymers with precisely designed molecular architectures and nanostructured morphologies in order to tune the
physical properties of materials for specific applications. The proposed project is focused on development of
photochemically induced atom transfer radical polymerization applicable in the presence of air under various
specific conditions. This will provide a huge step toward making this technique an environmentally friendly and
industrially viable process for preparation of materials and nanomaterials for various applications including
biomedicine. |
Towards lithium based batteries with improved lifetime
Pokročilé lítiové batérie s dlhou životnosťou
| Duration: |
1.7.2021 - 30.6.2025 |
| Program: |
SRDA |
| Project leader: |
Dr. rer. nat. Šiffalovič Peter DrSc. |
| Annotation: | With the steadily increasing energy requirements of portable electronics and electromobility, conventional lithiumion
batteries are facing new challenges. In the proposed project, we aim to stabilize the capacity and lifetime of
lithium-ion batteries employing ultra-thin interfacial layers prepared by means of atomic layer deposition (ALD). The
primary functions of interfacial layers are: i) preventing the dissolution of the cathode materials into electrolyte and
ii) stabilizing the cathode morphology during lithiation and de-lithiation. Although the positive effect of ALD
fabricated interfacial layers has already been demonstrated, systematic studies are still missing. The main
bottleneck of such studies is the identification of appropriate feedback analytical techniques that enable real-time
and in-operando insights into the charging/discharging mechanisms on the nanoscale. The conventional
electrochemical characterization methods can only provide hints on the ongoing mechanism during degradation
processes. Here we propose to utilize in-operando small-angle and wide-angle X-ray scattering (SAXS, WAXS) to
track the morphology and phase changes that occur during the charging/discharging of lithium-ion batteries in realtime.
The main focus of this project is on the application of real-time SAXS/WAXS studies under laboratory
conditions. In these circumstances, extensive, systematic studies of various ALD interfacial layers can be
performed. |
Comparison between silibinin-conjugated gold nanospheres and nanobipyramids impacts on the treatment of liver fibrosis in vivo.
Porovnanie účinku nanosfér a nanobipyramíd zlata konjugovaných so silibinínom pri liečbe fibrózy pečene in vivo.
| Duration: |
1.1.2022 - 31.12.2025 |
| Program: |
VEGA |
| Project leader: |
Mgr. Šelc Michal PhD. |
| Annotation: | Liver fibrosis occurs as a result of chronic liver damage associated with the accumulation of extracellular matrix proteins. It is the common outcome of various infectious and non-infectious diseases and represents a global health problem resulting from the high global prevalence and limited treatment options. Treatment of liver fibrosis is essential to prevent the development of liver cirrhosis and hepatocellular carcinoma, however, there is no effective pharmaceutical intervention to date for the treatment of this disease. One of the promising but yet barely explored approach to treat the liver fibrosis is offered by the targeted therapy using nanomaterials coated with an antifibrotic drug. In case of inorganic nanomaterials, spherical gold nanomaterials are being investigated for this aim. Interestingly nanomaterials of other shapes (e.g. nanobipyramids) could possess even better diagnostic and therapeutic features due to their unique physical-optical properties. |
Preparation and study of porous and non-porous aluminium anode for the purpose of increasing the performance of the primary Al-air battery.
Príprava a štúdium poréznej a neporéznej hliníkovej anódy pre účely zvýšenia výkonu primárnej Al-vzduch batérie.
| Duration: |
1.1.2022 - 31.12.2024 |
| Program: |
VEGA |
| Project leader: |
Mgr. Šimon Erik PhD. |
| Annotation: | Metal-air batteries are considered as candidate a new generation of energy storage system which has a potential
to substitute or supplement daily used Li-ion batteries. As suitable candidate is appeared Al-air battery for low
cost, abundance and recyclability of aluminium. The submitted project is focused on the preparation and study of
a porous aluminium anode as well as their porous and non-porous alloys. The porous aluminium anode will be
prepared by methods of powder metallurgy, the resulting porous structure in the form of a solid solution (in the
case Al alloys). The porous structure will be achieved by partial sintering of the aluminium powders and
subsequent rapid cooling. The process of powder metallurgy will be also used for preparation non-porous
aluminium alloys in the form of non-equilibrium supersaturate state. As input powders, pure Al powders (99.99%),
binary aluminium alloy powders (Al/Zn, Al/Sn) and ternary aluminium alloy powders (Al/Zn/Mg, Al/Sn/Mg,
Al/Zn/Sn) will be used. |
Nanomedical approach to fight pancreatic cancer via targeting tumorassociated carbonic anhydrase IX
Využitie nanomedicíny v boji proti rakovine pankreasu prostredníctvom zacielenia nádorovo-asociovanej karbonickej anhydrázy IX.
| Duration: |
1.7.2021 - 30.6.2025 |
| Program: |
SRDA |
| Project leader: |
Dr. rer. nat. Šiffalovič Peter DrSc. |
| Annotation: | Pancreatic cancer is a lethal disease with a rising incidence and mortality and it is the fourth leading cause of
cancer-related deaths in Europe. The median survival time of pancreatic cancer is 4-6 months after diagnosis, the
lowest survival rate of all cancers. Only 20% of diagnosed cases are operable. Photothermal therapy (PTT) has the
potential to become a new frontrunner in the fight against pancreatic cancer. This cutting-edge biomedical
application relies on the rapid heating of the plasmonic nanoparticles induced by laser light absorption, followed by
an increase in the ambient temperature around the nanoparticles. The effect of the localized surface plasmon
resonance (LSPR) can be observed only in a special class of nanoparticles. Photothermal therapy results in
selective hyperthermia and irreversible damage of the tumor while avoiding damage to healthy tissue.
However, the delivery efficiency of plasmonic nanoparticles is often insufficient. It can be increased by a dedicated functionalization of the plasmonic nanoparticles with ligands (antibodies) that selectively recognize the cancer cells.
One of the main aims of the proposed project is to increase the delivery efficiency of the plasmonic nanoparticles
for PTT by functionalization with antibodies that selectively recognize the tumor in the body. A promising target for
functionalized nanoparticles is carbonic anhydrase IX, a hypoxia biomarker associated with an aggressive
phenotype. CA IX is expressed in many types of tumors, while being absent from adjacent healthy tissue, making it
an ideal highly specific candidate for anti-cancer therapy target. CAIX is abundantly expressed on the surface of
pancreatic cancer cells where it correlates with a poor patient outcome. Targeting pancreatic cancer via
nanomaterials-based approach combined with anti-CAIX antibody ensures highly selective application of PTT with
potential benefits in the clinical environment. |
Development of unique TiMg composite dental implant
Vývoj unikátneho TiMg kompozitného zubného implantátu
| Duration: |
1.7.2021 - 30.6.2025 |
| Program: |
SRDA |
| Project leader: |
Mgr. Švastová Eliška PhD. |
| Annotation: | Dental implants (Dis) become more affordable and sought solution across a globe, the will be in a place for longer
periods and a need for maintenance will decrease. Titanium (Ti) and Ti alloys are the most widely utilized materials
for production of DI. Even though Ti-based DI are used with a high success rate, two major issues have remained
insufficiently resolved: the stress-shielding effect and their insufficient surface bioactivity. That pushes competition,
progress and R&D in the related area further and brings a need for novel solutions, approaches and material
concepts.
The main aim of proposed project is a development of an innovative endosseous biomedical DI fabricated from the
unique partially biodegradable Ti - magnesium (Mg) composite material. New DI will minimize the main drawbacks
of the contemporary DI, while it maintains the mechanical performance and fatigue endurance of Ti-based
references. An advantageous combination of the mechanical, fatigue, corrosion and biological properties of
developed DI is owing to a special DI`s design, which reflects and takes advantage of Ti17Mg, the material it will be
manufactured from. Ti17Mg is the experimental powder metallurgy material invented by project partners, which selectively exploits the advantages of both biometals. In the project a new DI will be designed and optimized, in
order to reflect unique behavior and workability of Ti17Mg. Performance of DI will be assessed and optimized
systematically in an environment, which simulates real-life conditions in a human body, including mechanical,
fatigue and corrosion testing, and in-vitro and in-vivo biological evaluation using cell culture, small and large animal
models. All assays will be carried out in accordance with related ISO specifications.
It is anticipated that at the end of the project new innovative high value-added DI is available and pending for
testing in a human body. Expectedly TRL 6 will be accomplished at the end of project. |
The total number of projects: 11
