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Institute: Institute of Measurement Science

European network for advancing Electromagnetic hyperthermic medical technologies.
Európska sieť pre pokrok v elektromagnetických hypertermických medicínskych technológiách
Program: COST
Project leader: Mgr. Teplan Michal PhD.
Annotation:Electromagnetic (EM) hyperthermic technologies hold great potential in the treatment of diseases, especially for cancers that are resistant to standard regimens. These technologies modify tissue temperature: hyperthermia heats the diseased tissue to make it susceptible to treatments, and ablation heats the tissue until it is destroyed. Hyperthermia is particularly effective in treatment of cervical and breast cancer, head and neck cancers, sarcoma in adults, and germ cell tumours in children; while radiofrequency and microwave ablation offer promise for treating liver, kidney, and lung cancers. Overall, these techniques have shown significant potential and there is substantial opportunity to solidify their use clinically and to apply them to a wider range of medical conditions. However, underpinning the development of these techniques is the need for accurate knowledge of the dielectric and thermal properties of tissues, which provide the foundation for these technologies and de-risk the technical challenge before commercialization. Furthermore, contributing to the stagnant market of EM hyperthermic medical devices is the fact that, often researchers working on the development of medical technologies are not fully aware of, and not trained to address, the clinical and commercialisation challenges facing novel medical devices. To address these challenges, the MyWAVE Action takes a holistic approach by bringing together key players in the field of dielectric spectroscopy, translational research, and medical professionals. Conjoining these varied communities into one collaborative network is critical to advance the design, development, and commercialisation of EM hyperthermic technologies, so that they can reach patients faster and improve treatment outcomes.
Duration: 4.9.2018 - 3.9.2022

Comparative imaging methods based on magnetic resonance
Komparatívne zobrazovacie metódy na báze magnetickej rezonancie
Program: Bilateral - other
Project leader: Prof. Ing. Frollo Ivan DrSc.
Annotation:Research of comparative imaging methods based on magnetic resonance for diagnostics of neurological and musculoskeletal diseases. Imaging of micro- and nanostructures based on magnetic resonance for biomedical and material research. Mutual visits of scientists and PhD students enabling them to perform imaging experiments on MRI instruments in the laboratories of partners in the appropriate time limits.
Duration: 1.3.2017 - 31.12.2020

Correlated Multimodal Imaging in Life Sciences
Korelované multimodálne zobrazovanie vo vedách o živej prírode
Program: COST
Project leader: RNDr. Hain Miroslav PhD.
Annotation:The network aims at fueling urgently needed collaborations in the field of correlated multimodal imaging (CMI), promoting and disseminating its benefits through showcase pipelines, and paving the way for its technological advancement and implementation as a versatile tool in biological and preclinical research. CMI combines two or more imaging modalities to gather information about the same specimen. It creates a composite view of the sample with multidimensional information about its macro-, meso- and microscopic structure, dynamics, function and chemical composition. Since no single imaging technique can reveal all these details, CMI is the only way to understand biomedical processes and diseases mechanistically and holistically. CMI relies on the joint multidisciplinary expertise from biologists, physicists, chemists, clinicians and computer scientists, and depends on coordinated activities and knowledge transfer between academia and industry, and instrument developers and users. Due to its inherently multidisciplinary and cross-functional nature, an interdisciplinary network such as this Action is indispensable for the success of CMI. Nevertheless, there is currently no European network in the field. Existing scattered efforts focus on correlated light and electron microscopy or (pre)clinical hybrid imaging. This Action will consolidate these efforts, establish commonly-accepted protocols and quality standards for existing CMI approaches, identify and showcase novel CMI pipelines, bridge the gap between preclinical and biological imaging, and foster correlation software through networking, workshops and open databases. The network will raise awareness for CMI, train researchers in multimodal approaches, and work towards a scientific mindset that is enthusiastic about interdisciplinary imaging approaches in life sciences.
Duration: 1.1.2019 - 11.10.2022

MULTI-modal Imaging of FOREnsic SciEnce Evidence (MULTI-FORESEE) - tools for Forensic Science
Multimodálne zobrazovanie dôkazov forenznej vedy - nástroje pre forenznú vedu
Program: COST
Project leader: RNDr. Hain Miroslav PhD.
Annotation:The main objective is to promote innovative, multi-informative, operationally deployable and commercially exploitable imaging solutions/technology to analyse forensic evidence. Forensic evidence includes, but not limited to, fingermarks, hair, paint, biofluids, digital evidence, fibers, documents and living individuals. Imaging technologies include optical, mass spectrometric, spectroscopic, chemical, physical and digital forensic techniques complemented by expertise in IT solutions and computational modelling. Imaging technologies enable multiple physical and chemical information to be captured in one analysis, from one 'specimen', with information being more easily conveyed and understood for a more rapid exploitation. The ‘enhanced’ value of the evidence gathered will be conducive to much more informed investigations and judicial decisions thus contributing to both savings to the public purse and to a speedier and stronger criminal justice system. Lack of knowledge sharing, standardised protocols and communication between Academia, End Users and industry has been a barrier to translational science in this field; the Action will use the unique networking and capacity-building capabilities provided by the COST framework to bring together their knowledge and expertise; this is paramount to engage in a synergistic approach to boost imaging technological developments, allowing scientifically sound, highly reliable and multi-informative intelligence to be provided to investigators, prosecutors and defence. COST support is crucial to conquer the challenge on short term basis and to provide a legacy to Europe to advance knowledge for the deployment of cutting edge, innovative and implementable imaging forensic science.
Duration: 1.8.2018 - 1.3.2021

Wearable Robots for Augmentation, Assistance or Substitution of Human Motor Functions
Nositeľné robotické zariadenia pre posilnenie, podporu alebo náhradu motorických funkcií človeka
Program: COST
Project leader: Doc. Ing. Přibilová Anna PhD.
Annotation:Wearable Robots (WRs) is an emerging field of personal devices that are integrated parts of human functioning, and that are constructed of typical robotic components such as actuators, sensors and control algorithms. Where conventional robots were typically intended for use in industrial environments to help in tedious and repetitive tasks and tasks requiring high precision, the situation is currently evolving to one where there is an increasing direct physical interaction between robot and human operator. The interaction with humans in WRs is not only physical, but also includes cognitive aspects, as in the interaction, control of functions is typically shared by human and machine. WRs can be used either to augment, train or supplement motor functions or to replace them completely. Wearable Robots operate alongside human limbs, as is the case in orthotic robots, exoskeletons or robotic suits. WRs are expected to find applications in Medical, Industrial and Consumer Domains, such as neuro-rehabilitation, worker support, or general augmentation. As WRs continuously interact with humans in multiple situations, Human Robot Interaction, Ergonomics, and Ethical, Legal and Societal (ELS) considerations, as well as early involvement of stakeholders are of essential interest. This Action focuses on the European integration of different underlying disciplines in science and engineering, as well as on engaging of stakeholders to improve WR technology and its societal impact.
Duration: 15.3.2017 - 14.3.2021

Novel integrated approaches for research of biomedical effects of pulsed electric fields
Nové integrované prístupy pre výskum biomedicínskych účinkov pulzných elektrických polí
Program: Inter-academic agreement
Project leader: Mgr. Teplan Michal PhD.
Annotation:Intense pulsed electric fields have already use and great further potential for novel applications in biomedicine and food industry. However, the mechanistic details of the action of pulsed electric fields on the plasma membrane and especially on the intracellular level are still not clear. This project is focused on theoretical and experimental characterization of the effects of pulsed electric fields from the level of subcellular biomolecular structures to a cellular level. We aim to develop and employ approaches based on impedance spectroscopy and chemiluminescence detection which will enable us to explore the most prominent bioeffects of pulsed electric fields in a real-time, non-invasive and label-free manner. The major technological novelty will be in the integration of these monitoring tools to an automatic programmable experimental platform. The results of the project will provide new methods in the research of effects of electromagnetic fields on living cells and will bring future medical applications closer to reality.
Duration: 1.1.2018 - 31.12.2020

Understanding and modeling compound climate and weather events
Porozumenie a modelovanie združených klimatických a meteorologických javov
Program: COST
Project leader: Mgr. Chvosteková Martina PhD.
Annotation:Hazards such as floods, wildfires, heatwaves, and droughts usually result from a combination of interacting physical processes that occur across multiple spatial and temporal scales. The combination of physical processes leading to an impact is referred to as a Compound Event. Examples of high-impact Compound Events include (i) droughts, heatwaves, wildfire and/or air pollution and their interactions involving a complex interplay between temperature, humidity and precipitation; (ii) extreme precipitation, river discharge and storm surge interactions, combining coastal storm processes with fluvial/pluvial and ocean dynamics; (iii) storms including clustering of major events leading to spatial and/or temporal dependence. Climate change alters many of these processes and their interaction, making projections of future hazards based on single driver analyses difficult. Impact studies considering only one driver usually fail to assess the extent of the impacts of Compound Events. It is thus not clear whether climate models can capture major changes in risk associated with Compound Events. Existing modelling approaches used to assess risk may therefore lead to serious mal-adaptation. DAMOCLES will (a) identify key process and variable combinations underpinning Compound Events; (b) describe the available statistical methods for modelling dependence in time, space, and between multiple variables; (c) identify data requirements needed to document, understand, and simulate Compound Events, and (d) propose an analysis framework to improve the assessment of Compound Events. DAMOCLES brings together climate scientists, impact modellers, statisticians, and stakeholders to better understand, describe and project Compound Events, and foresees a major breakthrough in future risk assessments.
Duration: 14.9.2018 - 13.9.2022

Preparation and study of the precursor properties for development of nanomaterials based on metal oxides
Príprava a štúdium vlastností prekurzorov pre vývoj nanomateriálov na báze oxidov kovov
Program: Bilateral - other
Project leader: RNDr. Cigáň Alexander CSc.
Annotation:The subject of common interest include the following main areas: 1. Technology of HTc superconducting oxides based on Yttrium, Bismuth, Thalium and Mercury - bulks, tapes and thin films. 2. Investigation of the physical properties of these materials with the help of magnetization measurements. 3. Common experiments performed with LTc SQUID gradiometric system (at IMS SAS, Bratislava) and LakeShore susceptometer (at the Department of Inorganic and Physical Chemistry, Ghent). 4. Publication of results on cooperative scientific activities.
Duration: 1.7.2016 - 31.12.2020

The total number of projects: 8