Výsledky 13. výzvy SAS-MOST Joint Research Projects (Taiwan)
Predsedníctvo SAV na svojom 6. zasadnutí dňa 9. decembra 2021 uznesením č. 192 schválilo financovanie pre víťazné projekty v rámci bilaterálnej vedeckej spolupráce medzi Slovenskou akadémiou vied (SAS) a Ministry of Science and Technology (MOST), Taiwan
13th Call for SAS-MOST Joint Research Projects
Cieľom výzvy bolo podporiť projektovú spoluprácu tímov zo SAV a výskumných inštitúcií na Taiwane. Podané projektové návrhy boli hodnotené paralelne Komisiou SAV pre vyhodnocovanie medzinárodných projektov a príslušným hodnotiacim výborom MOST, Taiwan.
Podaných bolo celkovo 8 projektových návrhov. SAV a MOST z nich vybrali dva návrhy, ktorých realizáciu podporia v rokoch 2022 - 2024:
Názov: Highly efficient and stable lead-free perovskite solar cells with optimized non-radiative recombination
Slovenský partner: Šiffalovič, Peter
Taiwanský partner: Galagan, Yulia
Abstrakt: The perovskite solar cells (PSCs) are recently received attention due to the outstanding increase of power conversion efficiency (PCE), which is already reaching 25.2%. High PCE and the potential of low-cost manufacturing using solution-based methods make PSC an excellent candidate to salve global energy issues. However, despite the many advantages, perovskite solar cells still remain within laboratories. Several critical issues need to be solved before perovskite solar celi technology enters the industria! stage and will go through the commercialization process. Among these issues are the instability of the halide perovskite absorber materials under ambient conditions and lead toxicity. In the project, we propose solutions to overcome these problems by replacement lead (Pb) by tin (Sn) to salve the toxicity issues and utilize mix-dimensional 20/30 Sn-based perovskites to salve stability problems. However, the wide bandgap energy of Sn-based perovskites and low out of-plane conductivity that characterizes 20 layered perovskites result in limited power conversion efficiency (PCE). In this project, all of the above-mentioned issues will be addressed by designing novel, highly efficient and stable lead-free 20 /30 perovskite absorbers and interface engineering by incorporating low-dimensional materials such as MXenes and post-growth HTL/ETL interfaces passivation. These developments will make it possible to achieve the projecťs goals, namely: high efficiency (PCE > 14%) and stability (lifetime > 1,000 hours under standard accelerated lifetime tests) of Lead-Free Perovskite Solar cells.
Názov: Anti-amyloid activity of zeolite-based composites and analysis with real-time 3D super-resolution imaging
Slovenský partner: Šipošová, Katarína
Taiwanský partner: Chen, Shean-Jen
Abstrakt: A common feature associated with most of neurodegenerative diseases, including Alzheimer’s disease is the formation of extended, β-sheet rich amyloid fibrils. Today, amyloid-related diseases are incurable and the treatment is only symptomatic without feasibility to stop or substantially delay the progressive consequences of the diseases. Magnetic nano/micro-particles based on clinoptilolite-type of natural zeolite (CZ) jointly developed are expected to serve synergistic therapy approaches act as carriers for controlled drug delivery/release, imaging and local heating in biological systems, that can effectively decompose the amyloid-like fibrillar structures. The micro and mesopores of the natural zeolite can serve as containers for delivering various drugs to the target site to release. Magnetic CZ (MCZs) will improve drug delivery process, real-time monitoring of drug distribution surrounding a targeting side of tissue, as well as the subsequent effects of the therapeutics on the progression of diseases. In addition, fluorescent MCZs in combination with ultrasonic, magnetic or laser irradiation effects will provide hyperthermia and photoreaction to achieve both diagnosis and therapy. The Taiwanese research team has been deeply cultivated in temporalfocusing multiphoton microscopy (TFMPM), which imaging frame rate can achieve up to a hundred hertz. We will use the deep learning method to improve the imaging frame rate for real-time biomedical analysis. Within this project, animal models (including genetic rodent models) will be utilized to develop a theranostic system for for inhibition and destruction of amyloid aggregates and super-resolution imaging of MZC induced amyloid aggregate inhibition/destruction effects by state-of-art temporally and spatially super-resolution 3D imaging technology.
Kontaktná osoba za SAV: Zuzana Černáková, +421 (0) 2 5751 0 118, firstname.lastname@example.org