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Project

Institute of Experimental Physics

International Projects

AZCAI - Anti-amyloid activity of zeolite-based composites and analysis with real-time 3d super-resolution imaging

Anti-amyloidná aktivita kompozitov na báze zeolitov a analýza so zobrazovaním vo vysokom rozlíšení a v reálnom čase

Duration: 1. 1. 2022 - 31. 12. 2024
Evidence number:SAS-MOST JRP 2021/2
Program: JRP
Project leader: RNDr., Ing. Šipošová Katarína PhD.
Annotation:A common feature associated with most of neurodegenerative diseases, including Alzheimer’s disease is the formation of extended, β-sheet rich amyloid fibrils. Today, amyloid-related diseases are incurable and the treatment is only symptomatic without feasibility to stop or substantially delay the progressive consequences of the diseases. Magnetic nano/micro-particles based on clinoptilolite-type of natural zeolite (CZ) jointly developed are expected to serve synergistic therapy approaches act as carriers for controlled drug delivery/release, imaging and local heating in biological systems, that can effectively decompose the amyloid-like fibrillar structures. The micro and mesopores of the natural zeolite can serve as containers for delivering various drugs to the target site to release. Magnetic CZ (MCZs) will improve drug delivery process, real-time monitoring of drug distribution surrounding a targeting side of tissue, as well as the subsequent effects of the therapeutics on the progression of diseases. In addition, fluorescent MCZs in combination with ultrasonic, magnetic or laser irradiation effects will provide hyperthermia and photoreaction to achieve both diagnosis and therapy. The Taiwanese research team has been deeply cultivated in temporal focusing multiphoton microscopy (TFMPM), which imaging frame rate can achieve up to a hundred hertz. We will use the deep learning method to improve the imaging frame rate for real-time biomedical analysis. Within this project, animal models (including genetic rodent models) will be utilized to develop a theranostic system for for inhibition and destruction of amyloid aggregates and super-resolution imaging of MZC induced amyloid aggregate inhibition/destruction effects by state-of-art temporally and spatially super-resolution 3D imaging technology.

Azobenzenes as potential Alzheimer's theranostic agents

Azobenzénové deriváty ako potenciálne terapeutiká pre Alzheimerovu chorobu

Duration: 1. 1. 2023 - 31. 12. 2024
Evidence number:Mobility SAS-PAS-22-13
Program: Mobility
Project leader: RNDr. Bednáriková Zuzana PhD.
Annotation:Amyloid fibrils of amyloid β (Aβ) peptides are a neuropathological feature of Alzheimer's disease (AD). AD is one of the world's fastest-growing neurological diseases with substantial economic and societal impact, but no cure is currently available. Therefore, the exploration of novel treatment approaches is in high demand. The project's main objective is to study the ability of azobenzene molecules to affect targets associated with the amyloid cascade of AD pathogenesis. The project will employ the lever-like potential of azobenzene molecules to dissociate fibrillar aggregates of Aβ peptides and inhibit the proteolytic activity of β-secretase. We will integrate in vitro, in silico, and cells workflow to find a possible alternative therapy against this devastating disease. Moreover, this collaborative research partnership will present an excellent opportunity for both teams' young members to learn new techniques in the well-equipped laboratories at the Polish and Slovak Academies of Sciences and gain new experience by working in an international scientific environment.

2DSOTECH - 2Dimensional van der Waals Spin-Orbit Torque Technology

Dvojrozmerná van der Waalsovská spinovo-orbitálna torzná technológia

Duration: 1. 12. 2021 - 29. 11. 2024
Program: ERANET
Project leader: RNDr. Gmitra Martin PhD.
Annotation:Engineering two-dimensional (2D) material van der Waals heterostructures by combining the best of different functional constituents can offer a plethora of opportunities in nanoelectronics. Here, we propose to develop all-2D spintronics platforms for the next generation of information technology based on 2D magnetic and topological spin-orbit materials. These hybrid systems can provide a strong synergy between spintronics and 2D materials, with the goal of combining “the best of both worlds”. Such integration of spin-orbit physics and magnetism in 2D heterostructures will enable groundbreaking functionalities in all-2D spin-orbit torque (SOT) technologies for low-power and non-volatile memory and logic devices. We will exploit low crystal symmetry of layered spin-orbit materials (SOM), hosting novel spin textures for the realization of efficient charge-to-spin conversion (CSC) with a significant out-of-plane spin-orbit field contribution for SOT technologies. We will start with basic investigation of CSC by using potentiometric methods in non-local spin valve geometry with graphene heterostructures. These studies will provide information about the main driving mechanisms of the CSC phenomena, such as the spin Hall, Rashba-Edelstein, or other spin-momentum locking effects to generate a giant and tunable spin polarization. Magnetic 2D crystals, on the other hand, exhibit a wide range of magnetic ordering and, extraordinarily, have the potential to be controlled by purely electronic means. Here, we will investigate 2D magnets for SOT technologies exploiting their low-dimensionality, perpendicular magnetic anisotropy, and the possibility of electric field control. We will examine the dynamics of magnetic excitations, their anisotropies, and controllability by gates, the critical parameters influencing the magnetic switching speed. This project will integrate 2D magnets and SOMs with engineered interfaces to establish exceptionally efficient SOT switching functionalities in all-2D materials platforms. We aim to study the fundamentals of magnetization dynamics and SOT switching behavior of hybrid structures using electronic, magnetotransport, time and spatially resolved magneto-optics, ferromagnetic resonance and 2nd harmonic measurements. The potential of the novel functionalities in these heterostructures will arise from the interplay of exotic spin textures, magnetic phases, proximity-induced exchange and spin-orbit effects at the interfaces of the 2D materials. These effects will be further controlled by interface engineering with a graphene interlayer, twist angle between the layers, and with external parameters such as electric field and pressure. These functionalities will be complemented with voltage-controlled magnetization switching in ultrathin devices. Finally, we will utilize these engineered hybrid devices to demonstrate ultra-fast and low-power magnetization switching of 2D magnets, for a future generation of all-2D SOT technologies.

The ALICE experiment at the CERN LHC: Study of the strongly interacting matter under extreme conditions

Experiment ALICE na LHC v CERN: Štúdium silno interagujúcej hmoty v extrémnych podmienkach

Duration: 1. 1. 2022 - 31. 12. 2026
Evidence number:MŠVVaŠ SR 0409/2022
Program: CERN/MŠ
Project leader: RNDr. Králik Ivan CSc.
Annotation:The project is aimed at the study of strongly interacting matter under extreme conditions of the p-p, p-Pb and Pb-Pb collisions at the energies of the LHC collider at CERN. The main program of the ALICE experimemt is the study of the quark-gluon plasma properties.

ATLAS KE - ATLAS experiment at LHC at CERN: deep-inelastic phenomenons and new physics at TEV energies

Experiment ATLAS na LHC v CERN: hlboko-nepružné javy a nová fyzika pri TeV energiách

Duration: 1. 1. 2022 - 31. 12. 2026
Evidence number:MŠVVaŠ SR 0408/2022
Program: CERN/MŠ
Project leader: RNDr. Stríženec Pavol CSc.

Innovative water-soluble phytomaterial inhibitors for Alzheimer’s and Parkinson’s disease prevention

Innovative water-soluble phytomaterial inhibitors for Alzheimer’s and Parkinson’s disease prevention

Duration: 1. 10. 2022 - 28. 2. 2025
Program: Horizont 2020
Project leader: MUDr. Musatov Andrey DrSc.

SeNaTa - Self-heating magnetic nanoconstructs for theranostic applications

Magnetické nanoštruktúrne materiály schopné samozahrievania pre teranostické aplikácie

Duration: 1. 7. 2023 - 30. 6. 2025
Evidence number:APVV DS-FR-22-0037
Program: Bilaterálne - iné
Project leader: RNDr. Kubovčíková Martina PhD.
Annotation:Cancer is still one of the leading causes of death worldwide, therefore significant research and innovation efforts are still needed to find new materials and methods for better cancer diagnosis and treatment. Magnetic nanoparticles (MNPs) appear to be a very promising material for use in many medical fields, such as in nanosurgery they can be used to kill tumor cells by increasing drug concentration in target cells in combination with hyperthermia as well. The presented project is focused on the development of new nanoconstructs labeled by radionuclide as a potential theranostic agent for radiotherapy and diagnostics. The first step to achieve the desired goal will be the synthesis of nanoconstructs consisting of self-heating magnetic nanoparticles coated with various biocompatible substances, which will exhibit the desired bioactivity as well. The prepared nanoconstructs will be studied by several physicochemical methods, and their stability and suitability for magnetic hyperthermia, i.e. the ability to produce heat in an alternating magnetic field, will be monitored. In the second step, nanoconstructs with the best properties will be radiolabeled with therapeutic 177Lu and diagnostic 99mTh radionuclides to prepare radioactive nanoconstructs for dual therapy and diagnosis. In the next step, in vitro toxicity testing of nanoconstructs labeled with radionuclides will be performed. The prepared magnetic magnetic nanostructured materials labeled with radionuclides will contribute to the improvement of diagnostics and therapy of cancer diseases. The project is based on a complex multidisciplinary approach, from physics, chemistry to biochemistry and biomedicine. The involved partners possess key skills, infrastructure and are highly motivated to achieve the project goals.

ML4NGP - Non-globular proteins in the era of Machine Learning

Neglobulárne proteíny v ére strojového učenia

Duration: 25. 10. 2022 - 26. 10. 2026
Evidence number:COST Action CA21160
Program: COST
Project leader: RNDr. Bednáriková Zuzana PhD.
Annotation:The ML4NGP Action aims to establish an interdisciplinary pan-European network to favour interplay between experiments and computation, fostering experimental frameworks designed to provide information to computational methods, and novel computational methods developed, trained and benchmarked with experimental data. ML4NGP will enhance the primary experimental data generation (WG1), promote integrative structural biology approaches (WG2), benchmark the state-of-the-art ML methods (WG3) and improve the functional characterization of NGPs (WG4). The Action will support its scientific objectives through policies that sustain free knowledge exchange, inclusiveness and training of young researchers who will lead future innovations in this field.
Project web page:https://www.cost.eu/actions/CA21160/

skQCI - skQCI

skQCI

Duration: 1. 1. 2023 - 31. 12. 2025
Evidence number: 10109154
Program: Digital Europe Programme
Project leader: RNDr. Skyba Peter DrSc.
Project web page:https://skqci.qute.sk/sk/slovencina/

JUICE-PEP-ACM - Slovak contribution to ESA-JUICE mission: Development of Anti-Coincidence Module ACM for Particle Environment Package PEP

Slovenský príspevok k misii ESA-JUICE: Vývoj anti-koincidenčného modulu ACM pre časticový komplex PEP

Duration: 15. 11. 2018 - 31. 12. 2024
Evidence number:ESA-PECS SK3-03
Program: European Space Agency (ESA)
Project leader: Ing. Baláž Ján PhD.,
Annotation:The ESA’s JUICE (JUpiter ICy moons Explorer) mission (http://sci.esa.int/juice) have to face to very hostile environment of Jovian radiation belts where the penetrating energetic electrons dominate. The Particle Environment Package (PEP) payload of this mission (http://sci.esa.int/juice/50073-science-payload ) was developed within a wide international collaboration led by Swedish Institute for Space Physics IRF in Kiruna. Due to limited available mass for efficient radiation shielding, the PEP payload will operate in rather unfavourable environment of penetrating energetic electrons that will affect the detection process inside the PEP/JDC (Jovian plasma Dynamics and Composition) sensor. To mitigate the unfavourable influence of the penetrating electron radiation to the plasma ions detection process, a concept of anti-coincidence module (ACM) has been identified within the PEP consortium. The project involves development of space-flight grade semiconductor solid state detector, the processing electronic board and a laboratory testing and calibration system RATEX-J (RAdiation Test EXperiment for JUICE). The JUICE probe has been successfully launched 14.4.2023 from space port Kourou. The PEP science suite has been successfuly commissioned in June 2023. The JUICE probe will be inserted into the orbit around Jupiter on 18. July 2031.

Structural, magnetic, and thermal investigations of novel functional materials

Structural, magnetic, and thermal investigations of novel functional materials

Duration: 1. 1. 2023 - 31. 12. 2024
Evidence number:PAS-SAS-2022-09
Program: Mobility
Project leader: RNDr. Mihálik Matúš PhD.
Annotation:The object of the collaboration is investigation of the magnetic, structural and thermodynamic properties of new magnetic materials such as manganites, magnetic oxides and molecule-based magnets. Of particular importance is the full physical characterization of functional materials with light-, temperature- or pressure-controlled properties as well as magnetic molecular nanosystems. Collaboration in this area between the Institute of Nuclear Physics PAS and the Institute of Experimental Physics SAS lasts for over fifteen years. We have carried out common studies of several molecular magnets, workers of INP PAN take regularly part in the triennial CSMAG conference organized in Košice. We are in possession of different but complementary measurement instruments. Therefore, the continuation of the joint project, aimed at a more comprehensive description and understanding of properties of new magnetic materials, would be purposeful.

SUPERQUMAP - SUPERCONDUCTING NANODEVICES AND QUANTUM MATERIALS FOR COHERENT MANIPULATION

Supravodivé nanozariadenia a kvantové materiály pre koherentnú manipuláciu

Duration: 6. 10. 2022 - 5. 10. 2026
Evidence number:COST CA211444
Program: COST
Project leader: prof., RNDr. Samuely Peter DrSc., akademik US Slovenska
Annotation:We propose a collaborative approach joining together efforts and groups all over Europe, structured around three pathways, (i) the synthesis and characterization of quantum materials with novel topological properties, (ii) the fabrication of sensors and devices exploiting novel superconducting functionalities and (iii) the generation and coherent manipulation of superconducting states that can create new opportunities in the superconducting quantum electronics. Using an open and inclusive approach that joins expertise and capabilities all over Europe, this project will structure collaborative efforts aiming at disruptive achievements in the field of superconductivity. The results will impact far beyond the development of new quantum solutions for computation, and include sectors such as health and energy.

Superconductivity in nitride thin films - materials for future quantum devices

Supravodivosť v tenkých filmoch nitridov - materiály pre budúce kvatové zariadenia

Duration: 1. 11. 2023 - 31. 10. 2024
Evidence number:2023-03-15-003
Program: Iné
Project leader: RNDr. Pristáš Gabriel PhD.
Annotation:The main aim of our common project is study superconductivity in nitride thin films. It was shown, that narrow NbN superconducting strips could be used for construction of ultrafast single photon detectors, which are expected to play important role in the secure quantum communications. Very recently, team from Montanuniversität Leoben succeeded in preparation of superconducting high entropy alloy (HEA) thin films and team from Slovak side preformed measurements of its superconducting properties. Preparation of nitride HEAs will be next step in effort to improve superconducting parameters of thin films for the purpose to be used in future quantum devices.

Vigil-ML - Study toward enhancing reliability and timeliness of Vigil mission predictions through Machine Learning

Štúdia smerujúca k zvýšeniu spoľahlivosti a včasnosti predikcií z dát misie Vigil pomocou strojového učenia

Duration: 1. 10. 2023 - 31. 12. 2025
Program: European Space Agency (ESA)
Project leader: RNDr. Mackovjak Šimon PhD.

Study of dynamics in interface region between space and Earth’s atmosphere

Štúdium dynamiky v oblasti rozhrania medzi vesmírom a atmosférou Zeme

Duration: 1. 1. 2023 - 31. 12. 2024
Evidence number:CAS-SAS-2022-07
Program: Mobility
Project leader: RNDr. Mackovjak Šimon PhD.

Exploring correlated and topological phases in layered van der Waals quantum materials

Výskum korelovaných a topologických fáz vo van der Waalsovských materiáloch

Duration: 1. 1. 2023 - 31. 12. 2024
Evidence number:HAS-SAS-2022-4
Program: Mobility
Project leader: Mgr. Szabó Pavol CSc.
Annotation:The project aims to explore novel quantum physics in heterostructures made of 2D materials focusing on emergent quantum phenomena induced by the spin-orbit coupling and its interplay with magnetism, topology, and superconductivity. We propose a study of van der Waals (vdW) heterostructures made of few-layer thin superconductors and ferromagnet and topological materials in order to study proximity effects on topologically induced superconductivity. The objective of the research is to build technological knowhow of sample preparation made of 2D materials, performing scanning tunneling microscopy and transport experiments which will be complemented by the state-of-the-art density functional theory calculations and tight-binding modeling of electronic structure to study quasiparticle interferences and transport properties.

RBS - Research on bulk superconductors

Výskum masívnych supravodičov

Duration: 1. 5. 2018 - 31. 12. 2026
Evidence number:1/2018
Program: Iné
Project leader: Ing. Diko Pavel DrSc., akademik US Slovenska
Annotation:The agreement on cooperation between IEP SAS and CAN Superconductorsis focused on research od REBCO bulk supercondyctors for practical applications.
Project web page:https://websrv.saske.sk/uef/oddelenia-a-laboratoria/laboratorium-materialovej-fyziky/

NOMAGRAD - Design of novel materials-based high performance magnetic gradiometer

Vývoj vysoko-citlivého magnetického gradiometra na báze nových magnetických materiálov

Duration: 1. 4. 2024 - 31. 3. 2027
Program: JRP
Project leader: RNDr. Škorvánek Ivan CSc.

PURPLEGAIN - Fundamentals and applications of purple bacteria biotechnology for resource recovery from waste

Základy a aplikácie purpurových baktérií v biotechnológií pre obnovu znečistených zdrojov

Duration: 10. 10. 2022 - 9. 10. 2026
Evidence number:COST Action CA21146
Program: COST
Project leader: RNDr. Pudlák Michal CSc.
Annotation:PURPLEGAIN aims to create a European network to share information, facilitating technology and knowledge transfer between the academic and industrial sectors, related to PPB applications for resource recovery from organic waste sources. Resource recovery includes wastewater or organic waste, open or closed environments, in single or chain processes. The network associates fundamental-focused and applied-research groups, improving lab-scale technology optimization through mechanistic modeling. It benefits the technology transfer from applied-research groups to industry, considerably improving process design.
Project web page:https://www.cost.eu/actions/CA21146/ https://purplegain.eu/

National Projects

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Analýza obrazových sekvencií metódami hlbokého učenia vo vybraných biofyzikálnych experimentoch

Duration: 1. 1. 2022 - 31. 12. 2024
Evidence number:VEGA 2/0101/22
Program: VEGA
Project leader: doc. Ing. Tomori Zoltán CSc.

Anomalous scaling in turbulent systems with symmetry breaking

Anomálne škálovanie v turbulentných systémoch s narušenou symetriou

Duration: 1. 1. 2021 - 31. 12. 2024
Evidence number:VEGA 2/0081/21
Program: VEGA
Project leader: RNDr. Jurčišin Marián PhD.
Annotation:Turbulent behavior belongs among basic properties of various macroscopic physical, chemical, biological, social-economical, financial, as well as environmental systems. Typical well-known examples of turbulent motions are various atmospheric phenomena (tornadoes, hurricanes, cyclones, etc.), turbulent streams in rivers and oceans, and turbulent motions in electrically conductive environments (motion of the outer earth core, solar wind, etc.) . The main task of theoretical investigations of turbulent systems is, first of all, the understanding of fundamental physical properties of turbulent flows that are common for all turbulent systems and which could potentially be applied in technical praxis in the future. In this respect, the main aim of the project is the investigation of the influence of breaking of various symmetries of developed turbulent environments on the properties of the anomalous scaling of correlation functions of fluctuating fields as well as on universal characteristics of turbulent systems.

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Dekoherencia v mechanických rezonátoroch pri nízkych teplotách

Duration: 1. 1. 2022 - 31. 12. 2025
Evidence number:VEGA 2/0093/22
Program: VEGA
Project leader: RNDr. Človečko Marcel PhD.

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Diskrétna gravitácia, kvantové javy a ich aplikácia na rôzne druhy fyzikálnej reality

Duration: 1. 1. 2023 - 31. 12. 2026
Program: VEGA
Project leader: RNDr. Pinčák Richard PhD.

HERO - -

Elektrokatalyzátory pre efektívnu produkciu vodíka pre budúce elektrolyzéry a palivové články

Duration: 1. 7. 2021 - 30. 6. 2025
Evidence number:APVV 20-0299
Program: APVV
Project leader: RNDr. Baťková Marianna PhD.
Annotation:The development of activities in the field of hydrogen technologies was also supported by the European Commission in the strategic document "Hydrogen Strategy for a Climate Neutral Europe". Today, Slovakia has suggested own national hydrogen strategy. Already in 2015, the National Hydrogen Association has founded to support research, implementation and use of hydrogen technologies. The Hydrogen Technology Center is being established in Košice with the main "Power-to-Gas" concept using renewable power energy sources with no negative impact on human life and without dependence on fossil fuels. A significant source of hydrogen is water and the electrolysis of water is the most promising technology for hydrogen production. However, before it can be recognized as an economically significant resource for large scale application with an exceptional energy potential, the simple, efficient, and secure methods of hydrogen retrieval have to be developed. For the time being, the most efficient electrocatalysts in terms of overpotential for hydrogen evolution reaction (HER) are noble metals. Unfortunately the high cost and scarcity of noble metals motivate the scientists to find the rival low-cost alternatives. Intrinsic structures of TMP meet the criteria of outstanding electrocatalysts that could further improve their HER performance in membrane electrode assembly. Excellent dispersity of electrocatalysts allows full use of active sites on catalysts to participate in electrode reaction to improve the electrocatalytic efficiency. Therefore, the main challenge in this project is to reduce the production cost of HER and at the same time to maintain the high efficiency of polymer electrode water electrolysis. Substantial aim of the project will be devoted to improve the PEM water electrolysis components mainly electrode materials based on modified carbon fibers electrocatalysts result in the technology which should be more approached to commercial markets.

Functionalized magnetic nanoparticles for MRI imaging of drug distribution in the lungs in experimental acute respiratory distress syndrome (ARDS)

Funkcionalizované magnetické nanočastice pre MRI zobrazovanie distribúcie liečiva v pľúcach pri experimentálnom syndróme akútnej respiračnej tiesne (ARDS)

Duration: 1. 1. 2023 - 31. 12. 2026
Evidence number:VEGA 2/0049/23
Program: VEGA
Project leader: Ing. Koneracká Martina CSc.
Annotation:The current project is focused on the synthesis and functionalization of magnetic nanoparticles (MNPs) for MRI imaging of the drug N-acetylcysteine distribution in the lungs in experimental acute respiratory distress syndrome (ARDS). The first step will be to prepare a conjugate consisting of MNPs modified with functional groups suitable for drug conjugation. MNPs functionalization and drug conjugation will be optimized and studied by physicochemical methods such as UV/Vis and IR spectroscopy, microscopy, calorimetry or magnetic measurements. In the next phase, the conjugate will be analyzed by MRI and compared with the properties of commercially available MRI contrast agents. In the third step, the relevant ARDS model will be created, and the conjugate will be applied to the lungs. Finally, the conjugate will be imaged using optimized MRI techniques to study the drug distribution in the lungs in ARDS. The output items of the project have a direct application potential for clinical practice.

Functional magnetic materials with perovskite structure based on rare earth and transition metal oxides

Funkčné magnetické materiály s perovskitovou štruktúrou na báze oxidov vzácnych zemín a prechodných kovov

Duration: 1. 1. 2022 - 31. 12. 2024
Evidence number:VEGA 2/0011/22
Program: VEGA
Project leader: RNDr. Mihalik Marián CSc.
Annotation:Part of our project deals with multiferroic materials and another with functionality of materials with perovskite structure in respect to hydrogen storage or application of colloid with nanoparticles for hyperthermia. The project is targeted to substitutional solid solutions and construction of magnetic phase diagrams in RTO3 system (R = Nd, Pr, Sm, Tb, Dy and T = Ti, Cr, Mn, Fe). Oxygen content affects physical properties of this system. The defect structure can be used for hydrogen storage. Experimental techniques like crystal growth of single crystals, synthesis of magnetic nanoparticles and study of various physical properties are complemented by theoretical approach using Density functional theory. Our project serves as starting point for re-examining the effect of oxygen content on physical properties of RMnO3 multiferroic compounds. The concept of storing hydrogen in the vacancies in these compounds is novel as well smart hyperthermia based on colloid containing magnetic nanoparticles of manganites.

Functional nano- and microwires with outstanding properties

Funkčné nano- a mikrodrôty s význačnými vlastnosťami.

Duration: 1. 1. 2023 - 31. 12. 2025
Evidence number:1/0180/23
Program: VEGA
Project leader: RNDr. Kováč Jozef CSc.
Annotation:The project is focused on the development and characterization of functional nano and microwires, which are characterized by distinctive features physical properties in the form of shape memory phenomenon, magnetocaloric phenomenon, magnetic bistability, etc. These properties can be used with advantages in the construction of miniature sensors and actuators for temperature, elongation etc. Scalable methods will be used to produce these materials (electrodeposition, Taylor Ulitovski method), which enable the preparation of a large number of samples and thus an easy transition to applications. The goal is to examine the most important parameters determining the functional properties, which enables the following phenomena modify from the point of view of working scope and amplitude. The shape of the wire brings shape to the mentioned phenomena anisotropy, which can highlight the functional properties in the selected direction and facilitates the subsequent application of the listed materials.

Interdisciplinary applications of cosmic rays observation and research in the laboratory of Institute of Experimental Physics of SAS at the Lomnicky stit observatory

Interdisciplinárne aplikácie pozorovania a výskumu kozmického žiarenia na pracovisku ÚEF SAV na Lomnickom štíte

Duration: 1. 1. 2022 - 31. 12. 2024
Evidence number:VEGA 2/0029/22
Program: VEGA
Project leader: Ing. Kubančák Ján PhD.
Annotation:The goal of the project is to create conditions for the further development of interdisciplinary applications of cosmic radiation research at the ÚEF SAS workplace on Lomnické štít, mainly through: a) maintaining continuity in the field of cosmic radiation observation, b) innovation and workplace development a c) intensive scientific cooperation and promotion of the workplace. The project will focus on the analysis and evaluation of data recorded by the neutron monitor and the SEVAN device during the 24th and the first third of the 25th solar cycle. Scientific work will be intensified in the field of cooperation in the field of radiation protection against cosmic rays and in the field of development and testing of detectors in mixed radiation fields occurring at high-altitude observatories. One of the results of the project will be a retrospective analysis of the increased or decreased intensity of secondary cosmic radiation in the atmosphere during periods with significant fluctuations in solar activity that occurred in the years 2014-2024.

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Iónové kvapaliny a hlboko eutektické zmesi ako modulátory stability a agregácie proteínov

Duration: 1. 1. 2022 - 31. 12. 2025
Evidence number:VEGA 2/0164/22
Program: VEGA
Project leader: RNDr. Fedunová Diana PhD.

Soft magnetic nanocrystalline materials prepared by unconventional thermal processing techniques

Magneticky mäkké nanokryštalické materiály pripravené nekonvenčnými technikami tepelného spracovania

Duration: 1. 1. 2023 - 31. 12. 2026
Evidence number:2/0148/23
Program: VEGA
Project leader: RNDr. Škorvánek Ivan CSc.

Magnetically modified textiles

Magneticky modifikovaný textil

Duration: 1. 7. 2023 - 30. 6. 2027
Evidence number:APVV-22-0060
Program: APVV
Project leader: doc. RNDr. Kopčanský Peter CSc.

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Mezoškálové javy v systémoch polymérnych a nepolymérnych látok a metodológia skúmania

Duration: 1. 1. 2023 - 31. 12. 2026
Program: VEGA
Project leader: RNDr. Sedlák Marián DrSc.

R1-Kareem Abdul - Misfolding proteins in amyloid diseases and their prevention/therapy

Misfolding proteins in amyloid diseases and their prevention/therapy

Duration: 1. 9. 2023 - 31. 8. 2027
Evidence number:09I03-03-V02-00039
Program: Iné projekty
Project leader: M. Tech. Kareem Abdul Hanan

NANOFLIT - Nano-functionalization of liquids for liquid-immersed transformers

Nano-funkcionalizácia kvapalín pre olejové transformátory

Duration: 1. 7. 2023 - 30. 6. 2027
Evidence number:APVV-22-0115
Program: APVV
Project leader: RNDr. Rajňák Michal PhD.
Annotation:The current increase in electricity consumption and the greening of its distribution, together with the increase in the price of materials for the production of distribution transformers, represent a challenge for applied research in electric power engineering. The intention of the presented project is to respond to this challenge by functionalizing the current liquids used in electrical transformers in order to increase their cooling efficiency while maintaining or improving their dielectric and insulating properties. For this project, the liquids used in the distribution transformers of the manufacturer interested in this research will be selected. These are commercial liquids primarily based on liquefied natural gas, synthetic and natural esters. Based on current state of the art, the liquids will be functionalized by means of nanotechnologies and nanomaterials, which can significantly improve thermal conductivity, natural and thermomagnetic convection, and thus make the overall heat transport in the liquids more efficient. The functionalizing nanoadditives will be mainly made from carbon (fullerene, nanodiamond) and iron oxides or other ferromagnetic elements. The functionalized liquids will undergo laboratory measurements of physico-chemical, electrical, magnetic and thermal properties. Based on the analyzes of laboratory experiments and numerical simulations, nanofluids with the greatest potential for improving the thermal and insulating properties of the transformer will be selected. The selected nanofluids will be tested by the industrial partner (the customer of the research results) and applied in the selected distribution transformer. The transformer will be subjected to electrical and temperature rise tests. One can expect that the nanofunctionalization of the liquids will result in a lower operating temperature of the transformer, which can lead to an extension of the transformer service life and to the production of smaller transformers.

Electromagnetically tunable structures in ferromagnetic cholesteric liquid crystals

Návratová projektová schéma

Duration: 1. 7. 2023 - 30. 6. 2024
Program: Iné projekty
Project leader: RNDr. Lacková Veronika PhD.

UNPROMAT - Novel nano/micro-structured metallic materials prepared by unconventional processing routes

Nové nano/mikroštruktúrované kovové materiály pripravené nekonvenčnými spôsobmi spracovania

Duration: 1. 7. 2020 - 30. 6. 2024
Evidence number:APVV-19-0369
Program: APVV
Project leader: RNDr. Škorvánek Ivan CSc.

Unraveling the early events of protein amyloid aggregation - from mechanism to therapy

Objasnenie počiatočných štádií amyloidnej agregácie proteínov - od mechanizmu k terapii

Duration: 1. 1. 2021 - 31. 12. 2024
Evidence number:2/0176/21
Program: VEGA
Project leader: doc. RNDr. Gažová Zuzana DrSc.
Annotation:Structural changes of poly/peptides leading to the formation of amyloid aggregates are associated with incurable diseases, like Alzheimer's disease or diabetes. While the general mechanisms of fibril formation and their characterization are well reported, the early events during poly/peptide fibrillation are still unclear. The project is focused on understanding the early events mechanisms leading to the formation of pre-fibrillar (partially un/folded intermediates, nuclei, oligomers) and fibrillar amyloid aggregates of selected globular and intrinsically disordered proteins. Our focus will be the study of the kinetics of pre-fibrillar structures formation, their morphology, and cytotoxicity, under various experimental conditions, and in the presence of selected interacting partners (small molecules, nanoparticles). The obtained results will contribute to understanding the early events of amyloid aggregation and identifying the inhibitors with therapeutic potential for amyloid diseases.

PRESPEED - Perspective electronic spin systems for future quantum technologies

Perspektívne elektrónové spinové systémy pre budúce kvantové technológie

Duration: 1. 7. 2021 - 30. 6. 2025
Evidence number:APVV-20-0150
Program: APVV
Project leader: RNDr. Vargová Hana PhD.
Annotation:The project is aimed at a comprehensive understanding of possibilities and limiting factors of electron spin systems for a quantum computation and quantum information processing, which will be investigated by the combination of advanced analytical and numerical methods including among others exact mapping transformations, localized-magnon theory, exact diagonalization, tensor-network methods, density functional theory, Monte Carlo simulations and density-matrix renormalization group method. In particular, we will examine the possibility to stabilize a bipartite and multipartite entanglement as a genuine quantum phenomenon needed for a quantum computation and quantum information processing at least up to temperature of liquid nitrogen or preferably room temperature. We will also explore the capability of the pulsed electron spin resonance for the spin-qubit manipulation. Quantum spin systems with topologically protected edge states eligible for a topological quantum computation will be investigated in detail together with a few selected quantum spin chains studied in connection with the implementation of a quantum teleportation. Frustrated Heisenberg spin systems supporting either the presence of a nontrivial skyrmion phase or magnon-crystal phases will be investigated in connection with the possibility to store a quantum information or to implement more complex quantum circuits. Heterostructures composed of atomically thin layers coupled by van der Waals forces will be examined with respect to a superconducting pairing and topological quantum computation. The studied electron spin systems will be either motivated by the effort to understand unconventional behavior of existing real magnetic materials or will be supplemented by the respective proposals for their experimental realization.

Self-organization processes in soft hybrid mixtures of liquid crystals and nanoparticles

Procesy samousporiadania v mäkkých hybridných zmesiach kvapalných kryštálov a nanočastíc

Duration: 1. 1. 2021 - 31. 12. 2024
Evidence number:2/0043/21
Program: VEGA
Project leader: RNDr. Tomašovičová Natália CSc.
Annotation:The proposal aims to approach the research of liquid crystals doped with nanoparticles of different kind from a novel perspective of the self-organization that has an indisputable importance covering all fields of natural sciences, and has also a deep impact in social sciences. In such composite systems a subtle interplay among the nanoparticles, the self-assembling matrix and the topological defects commands the self-organization process. We will focus on the electric/magnetic field induced self-organization in such systems experimentally on different length scales by investigating the processes in different phases, isotropic, nematic, cholesteric with the anticipation that our results can be exploited in applications such as guided material transport, magnetic/electric switches/sensors, chemical/biosensors, in microfluidic/lab-on-a-chip devices, etc. We are convinced that systematic studies in this topic may change fundamentally current knowledge.

Heavy quark production as a probe of Quantum Chromodynamics

Produkcia ťažkých kvarkov ako sonda kvantovej chromodynamiky

Duration: 1. 1. 2022 - 31. 12. 2025
Evidence number:VEGA 2/0020/22
Program: VEGA
Project leader: doc. RNDr. Nemčík Ján CSc.
Annotation:The present project is focused on further development and testing of theoretical descriptions of various phenomena inherent in quantum chromodynamics (QCD) in close connections to recent phenomenological models of particle physics. The main emphasize is devoted to investigation of several fundamental aspects of QCD dynamics in production of heavy quarks, mainly in diffractive quarkonium electroproduction on proton and nuclear targets at large energies highly relevant for ongoing measurements at the Large Hadron Collider and with the preparation of physics program for newly approved Electron-Ion Collider.

MikroFlex - -

Pružné mikroštruktúry a mikroroboty pre biomedicínske labon-chip aplikácie

Duration: 1. 7. 2022 - 30. 6. 2026
Evidence number:APVV-21-0333
Program: APVV
Project leader: doc. Ing. Tomori Zoltán CSc.
Annotation:The development boom of biomedical lab-on-chip (LOC) applications during the last two decades brought the need for the miniaturization of conventional mechanical actuators, sensors, and manipulators. Light-driven mechanical microstructures, trapped and moved by optical tweezers, can be easily integrated into the microfluidic LOC environment. The vast majority of light-driven microstructures is prepared by two-photon polymerization. It is the main objective of the present project to exploit the possibilities of working with flexible (deformable) microstructures, which were not used in biomedical applications, yet. Two well-defined LOC application areas are targeted: micro-rheology and single-cell manipulation. Micro-viscometers utilizing the effect of the surrounding fluid medium on the deformation (deflection) of flexible micro-cantilevers will be developed. The novel viscometer devices will be either anchored to the bottom glass surface or kept mobile and optically transportable inside the micro-fluidic system. Light-driven elastic micro-robots will be designed and tested for capture, transport, and release of single live cells. The operation of the developed micro-manipulators will be automated to build multicellular systems, mimicking the tissue conditions, in an autonomous way. To facilitate the flexible microstructure development and optimization, the material properties of the photo-polymers will be determined by comparing experimental deformation data with the results of numerical simulations.

REBCOAPL - -

REBCO masívne supravodiče na báze Y, Gd, Sm a Eu pre praktické aplikácie

Duration: 1. 7. 2022 - 30. 6. 2026
Evidence number:APVV-21-0387
Program: APVV
Project leader: Ing. Diko Pavel DrSc., akademik US Slovenska
Annotation:The project is focused on research and development of selected REBCO bulk singlegrain superconductors (BSS). We will examine YBCO, GdBCO, SmBCO and EUBCO systems, which are currently preferred in terms of mastering their production technology and specific applications. Based on our latest results, we will focus on the alloying of LREBCO (LRE- light rare earths) with elements that suppress Ba/LRE substitution in the crystal lattice, the addition of nanocrystalline BaCeO3, the bimodal size distribution of pining centres and the configuration of holes in REBCO BSS. We will apply the research results in the development of BSS production technology with optimized superconducting and mechanical properties. The use of the research and development results achieved within the project is expected by the manufacturer BSS CAN Superconductors s.r.o.
Project web page:https://websrv.saske.sk/uef/oddelenia-a-laboratoria/laboratorium-materialovej-fyziky/

BULKREBCO - Structure, superconducting and mechanical properties ov bulk REBCO superconductors

Štruktúra, supravodivé a mechanické vlastnosti masívnych REBCO supravodičov

Duration: 1. 1. 2022 - 31. 12. 2024
Evidence number:VEGA 2/0094/22
Program: VEGA
Project leader: Ing. Diko Pavel DrSc., akademik US Slovenska
Annotation:The project is focused on the research of the influence of the structure on the superconducting and mechanical properties of the REBCO bulk single grain superconductors (BSS). The effect of the bimodal particle size distribution of RE211 particles in the REBCO single crystal will be studied, as well as the effect of alloying. Acquired the knowledge will serve to optimize the preparation parameters and structure of REBCO BSS so that they are achieved the combination of a high value of the trapped magnetic field and levitation force with increased mechanical strength. We will use experimental methods of powder metallurgy, bulk single crystal growth, X-ray diffraction, light and electron microstructure analysis, magnetization measurements, measurements of trapped magnetic field and strength measurement. The project will be solved in cooperation with leading foreign laboratories within the formal (SIT Tokyo, JTU Shanghai, CAN Superconductors) and informal (University of Cambridge, CRISTMAT Caen, FzÚ Praha, ) cooperation.
Project web page:https://websrv.saske.sk/uef/oddelenia-a-laboratoria/laboratorium-materialovej-fyziky/

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Štúdium a modifikácia vlastností pavúčieho proteínu nadprodukovaného v Escherichia coli

Duration: 1. 1. 2022 - 31. 12. 2025
Evidence number:VEGA 2/0034/22
Program: VEGA
Project leader: RNDr., Ing. Šipošová Katarína PhD.

Theoretical study of frustrated magnetic systems

Teoretické štúdium frustrovaných magnetických systémov

Duration: 1. 7. 2021 - 30. 6. 2025
Evidence number:APVV-20-0293
Program: APVV
Project leader: RNDr. Jurčišin Marián PhD.

Theoretical study of cooperative phenomena in strongly correlated electron and spin systems

Teoretické štúdium kooperatívnych javov v silne korelovaných elektrónových a spinových systémoch

Duration: 1. 1. 2022 - 31. 12. 2025
Evidence number:VEGA 2/0037/22
Program: VEGA
Project leader: RNDr. Farkašovský Pavol DrSc.
Annotation:The proposed project is devoted to the theoretical study of cooperative phenomena in strongly correlated electron and spin systems. The special attention will be paid to specifying the key mechanisms which lead to formation and stabilization of inhomogeneous charge and spin ordering, superconductivity, itinerant ferromagnetism, ferroelectric and magnetocaloric phenomenon due to the big application potential of these phenomena and their possible coexistence. The study will be performed on comprehensive model, which will take into account all relevant interactions in rare-earth and transition metal compounds, where besides the spin-independent Coulomb interaction in d and f band also the spin dependent (double exchange) interaction between both bands will be included. For a solution of this model we plan to elaborate new numerical methods, which will be subsequently used in combination with standard methods of quantum statistical physics (DMRG and QMC) to study the above mentioned phenomena.

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Teoretické štúdium vlastností geometricky a interakčne frustrovaných magnetických systémov

Duration: 1. 1. 2023 - 31. 12. 2026
Program: VEGA
Project leader: RNDr. Jurčišinová Eva PhD.

TopoSQ2D - Topological superconductivity in quantum two-dimensional devices

Topologická supravodivosť v kvantových dvojrozmerných zaradieniach

Duration: 1. 4. 2022 -
Evidence number:IM-2021-42
Program: IMPULZ
Project leader: RNDr. Gmitra Martin PhD.
Annotation:The project aims to explore quantum physics in van der Waals 2D materials focusing on discovery of emergent quantum phenomena induced by the spin-orbit coupling and its interplay with magnetism, topology and superconductivity. For this purpose we establish a new Quantum Materials research laboratory with tightly merged theoretical expertise in spin-orbit coupling and experimental expertise in superconductivity. Research will be focused on investigating electronic properties of the prepared heterostructures in normal and superconducting phases using scanning tunneling microscopy and magnetotransport measurements. The theory will be intended for calculation of electronic structure from first-principles and quasiparticle interference spectra and transport properties in order to interpret experimental results and guide further experiments. The studied systems will be further recast towards proof-of-principle devices utilizing topological aspects of superconductivity relevant for quantum computations.

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Topologicky netriviálne magnetické a supravodivé nanoštruktúry

Duration: 1. 7. 2021 - 30. 6. 2025
Evidence number:APVV-20-0425
Program: APVV
Project leader: prof., RNDr. Samuely Peter DrSc., akademik US Slovenska

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UA-Oganesyan

Duration: 1. 1. 2023 - 30. 6. 2024
Evidence number:UA00052
Program: Iné projekty
Project leader: prof. Oganesyan Koryun DrSc.

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UA-Vitushkina

Duration: 1. 1. 2023 - 30. 6. 2024
Evidence number:UA00051
Program: Iné projekty
Project leader: doc. Vitushkina Svitlana PhD.

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Viaczložkové ligandy ako modulátory cieľov spojených s patogenézou Alzheimerovej choroby

Duration: 1. 7. 2023 - 30. 6. 2027
Program: APVV
Project leader: doc. RNDr. Gažová Zuzana DrSc.

The development of translationally relevant regenerative and reparative strategies after spinal cord trauma

Vývoj translačne relevantných regeneračných a reparatívnych stratégií po traumatickom poranení miechy

Duration: 1. 7. 2020 - 30. 6. 2024
Evidence number:APVV-19-0324
Program: APVV
Project leader: MUDr. Musatov Andrey DrSc.

Projects total: 53