Project
Institute of Neuroimmunology
International Projects
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Alzheimer's Disease Diagnostics Innovation and Translation to Clinical Practice in Central Europe
| Duration: | 1. 1. 2023 - 31. 12. 2026 |
| Evidence number: | 101087124 — ADDIT-CE |
| Program: | Horizont Európa |
| Project leader: | doc. MVDr. Žilka Norbert DrSc. |
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Double-edged sword of Parkinson's disease: the study of extracellular vesicles as a mediator of pathology spreading and uniquesource of early diagnostics data
| Duration: | 1. 5. 2023 - 30. 4. 2026 |
| Evidence number: | CRP/SVK22-04_Ec |
| Program: | ICGEB |
| Project leader: | MUDr. RNDr. Fričová Dominika PhD. |
INTERTAU - Integrative structural biology of pathological tau protein, an appealing therapeutic target for Alzheimer´s disease modifying drugs
Integrative structural biology of pathological tau protein, an appealing therapeutic target for Alzheimer´s disease modifying drugs
| Duration: | 1. 6. 2022 - 30. 6. 2025 |
| Evidence number: | 873127 |
| Program: | Horizont 2020 |
| Project leader: | RNDr. Škrabana Rostislav PhD. |
Multi-MeMo - Shorter- and longer-term mechanisms of multimodal interventions to prevent dementia
Krátkodobý a dlhodobý mechanizmus multimodálnej intervencie pre prevenciu demencie
| Duration: | 1. 4. 2023 - 30. 6. 2026 |
| Evidence number: | JPND2022-111 |
| Program: | Horizont Európa |
| Project leader: | MUDr. Novák Petr PhD. |
Neu-Vasc - Neurovascular damage determines disease pathophysiology in pediatric mild traumatic brain injury: source of new biomarkers
Neurovaskulárne poškodenie určuje patofyziológiu ochorenia u detských pacientov po traumatickom poškodení mozgu: zdroj nových biomarkerov
| Duration: | 1. 1. 2020 - 31. 12. 2025 |
| Evidence number: | JTC2019: Neu-Vasc |
| Program: | ERANET |
| Project leader: | doc. RNDr. Filipčík Peter CSc. |
| Annotation: |
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Non-globular proteins in the era of Machine Learning
| Duration: | 1. 10. 2022 - 31. 10. 2026 |
| Evidence number: | CA21160 |
| Program: | COST |
| Project leader: | Ing. Cehlár Ondrej PhD. |
PROGRESS - Disease-predisposing or resilience-promoting? Decoding the systems biology and behavioural predictors and determinants of the tipping point of stress
Predisponujúce k chorobám alebo podporujúce odolnosť? Dekódovanie biológie systémov, markerov a determinantov bodu zlomu stresu
| Duration: | 1. 12. 2023 - 30. 11. 2026 |
| Evidence number: | NEURON II/2023/77 |
| Program: | ERANET |
| Project leader: | prof. Ing. Jurišica Igor DrSc. |
premodiALS - A premotor disease signature for ALS
Rukopis pre-motorického štádia amytrofnej laterálnej sklerózy
| Duration: | 1. 9. 2022 - 31. 8. 2025 |
| Evidence number: | JPND2021-650-122 |
| Program: | Horizont 2020 |
| Project leader: | doc. MVDr. Žilka Norbert DrSc. |
Antineuropatho - Developing novel nanopharmaceutics against bacterial infections at center nervous system
Vývoj nových nanoliečiv proti bakteriálnym infekciám v centrálnom nervovom systéme
| Duration: | 1. 1. 2022 - 31. 12. 2024 |
| Evidence number: | ENM III/2021/165 |
| Program: | ERANET |
| Project leader: | prof. MVDr. Bhide Mangesh Ramesh PhD. |
National Projects
Analysis of Psychoneuroimmunological Parameters of Health in Specific Population Groups in Slovakia
Analýza psychoneuroimunologických parametrov zdravia vo vybraných skupinách slovenskej populácie
| Duration: | 1. 7. 2023 - 30. 6. 2027 |
| Evidence number: | APVV-22-0160 |
| Program: | APVV |
| Project leader: | prof. RNDr. Kontseková Eva DrSc. |
Whole-of-societal Impact of Traumatic Brain Injuries in Slovakia
Celospoločenský dopad úrazov mozgu v Slovenskej Republike
| Duration: | 1. 7. 2023 - 30. 6. 2026 |
| Evidence number: | APVV-22-0613 |
| Program: | APVV |
| Project leader: | RNDr. Čente Martin PhD. |
The double-edged sword of the plasminogen system: From homeostasis maintenance to COVID-19
Dvojsečný meč plazminogénového systému: Od udržiavania homeostázy po COVID-19
| Duration: | 1. 8. 2021 - 30. 6. 2025 |
| Evidence number: | APVV-20-0513 |
| Program: | APVV |
| Project leader: | RNDr. Škrabana Rostislav PhD. |
Identification of novel biomarkers and signaling pathways after traumatic brain injury
Identifikácia nových biomarkerov a signálnych dráh po traumatickom poranení mozgu
| Duration: | 1. 1. 2023 - 31. 12. 2026 |
| Evidence number: | 2/0086/23 |
| Program: | VEGA |
| Project leader: | RNDr. Čente Martin PhD. |
Interaction of the brain and intestine in conditions of Alzeheimer's type neurodegeneration
Interakcia mozgu a čreva v podmienkach neurodegenerácie Alzeheimerovho typu
| Duration: | 1. 1. 2022 - 31. 12. 2024 |
| Evidence number: | 2/0127/22 |
| Program: | VEGA |
| Project leader: | MVDr. Mgr. Smolek Tomáš PhD. |
Aggregation prone conformation of protein tau targetable by specific antibodies
K agregácii náchylná konformácia proteínu tau rozpoznateľná špecifickými protilátkami
| Duration: | 1. 1. 2023 - 31. 12. 2026 |
| Evidence number: | 2/0125/23 |
| Program: | VEGA |
| Project leader: | Ing. Cehlár Ondrej PhD. |
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Laktoferín a laktofericín ako prirodzené inhibítory plazmínu: Od určenia štruktúry po terapeutické aplikácie
| Duration: | 1. 1. 2021 - 31. 12. 2024 |
| Evidence number: | 2/0152/21 |
| Program: | VEGA |
| Project leader: | RNDr. Škrabana Rostislav PhD. |
Longitudinal monitoring of adaptive immunity after SARS-CoV -2 infection and vaccination: markers of imunity
Longitudinálne monitorovanie adaptívnej imunity po infekcii SARS-CoV-2 a očkovaní: markery imunity
| Duration: | 1. 7. 2022 - 30. 6. 2025 |
| Evidence number: | APVV-21-0478 |
| Program: | APVV |
| Project leader: | prof. RNDr. Kontseková Eva DrSc. |
Longitudinal Assessment of Neurodegeneration and the Correlates of Relevant Endpoints in AD
Longitudinálne pozorovanie neurodegenerácie a korelátov relevantných ukazovateľov v Ach
| Duration: | 1. 7. 2021 - 30. 6. 2024 |
| Evidence number: | APVV-20-0447 |
| Program: | APVV |
| Project leader: | MUDr. Novák Petr PhD. |
Small ordered motifs in regulation of pathophysiology of disordered protein tau
Malé štruktúrované motívy ako regulátory patofyziológie prirodzene neusporiadaného tau proteínu
| Duration: | 1. 7. 2022 - 30. 6. 2025 |
| Evidence number: | APVV-21-0479 |
| Program: | APVV |
| Project leader: | RNDr. Škrabana Rostislav PhD. |
Management of Brain Injury Risks in Contact Sport Players - Diagnosis and Prevention of Neurodegeneration
Manažment rizík poranenia mozgu u hráčov kontaktných športov – diagnostika a prevencia neurodegenerácie
| Duration: | 1. 7. 2023 - 30. 6. 2026 |
| Evidence number: | APVV-22-0470 |
| Program: | APVV |
| Project leader: | doc. RNDr. Filipčík Peter CSc. |
Molecular pathways induced by traumatic brain injury: novel biomarkers and prediction of new therapeutic targets for neurodegeneration
Molekulové dráhy indukované traumatickým poškodením mozgu: identifikácia nových biomarkerov a potenciálnych terapeutických cieľov pre neurodegeneráciu
| Duration: | 1. 7. 2021 - 30. 6. 2024 |
| Evidence number: | APVV-20-0615 |
| Program: | APVV |
| Project leader: | doc. RNDr. Filipčík Peter CSc. |
Engineering the nano-therapeutics against West Nile virus- A model to contend neuroinfections
Navrhovanie nanoterapeutík proti Západonílskemu vírusu - Ako model v boji proti neuroinfekciám
| Duration: | 1. 1. 2021 - 31. 12. 2024 |
| Evidence number: | 2/0128/21 |
| Program: | VEGA |
| Project leader: | Kulkarni Amod M.Sc., PhD. |
Neuro-glia cell-based model for inter-neuronal spread of tau pathology
Neuro-gliový multi-bunkový model pre šírenie tau patológie
| Duration: | 1. 7. 2021 - 30. 6. 2025 |
| Evidence number: | APVV-20-0585 |
| Program: | APVV |
| Project leader: | RNDr. Žilková Monika PhD. |
New therapeutic targets for treatment of traumatic brain injury and their validation in animal model of chronic neurodegeneration
Nové terapeutické ciele pre liečbu traumatického poškodenia mozgu a ich validácia v animálnom modeli chronickej neurodegenerácie
| Duration: | 1. 1. 2022 - 31. 12. 2024 |
| Evidence number: | 2/0153/22 |
| Program: | VEGA |
| Project leader: | doc. RNDr. Filipčík Peter CSc. |
Novel insights into Tauopathy mechanism: lipids as a tool to control neurodegeneration and neuroinflammation
Nový pohľad na mechanizmus tauopatií: lipidy ako nástroj na kontrolu procesu neurodegenerácie a neurozápalu
| Duration: | 1. 7. 2023 - 30. 6. 2026 |
| Evidence number: | APVV-22-0313 |
| Program: | APVV |
| Project leader: | Mgr. Majerová Petra PhD. |
Novel receptor-mediated delivery system for brain therapeutics
Nový receptorom sprostredkovaný systém pre transport liečiv do mozgu
| Duration: | 1. 7. 2022 - 30. 6. 2025 |
| Evidence number: | APVV-21-0254 |
| Program: | APVV |
| Project leader: | Ing. Hanes Jozef DrSc. |
Novel receptor-mediated delivery system for brain therapeutics
Receptorom sprostredkovaný transport liečiv cez hematoencefalickú bariéru do mozgu
| Duration: | 1. 1. 2022 - 31. 12. 2024 |
| Evidence number: | 2/0078/22 |
| Program: | VEGA |
| Project leader: | PharmDr. Kováč Andrej PhD. |
Spread of alpha-Synuclein-associated pathology across gastrointestinal organs in a mouse model and patients with Parkinson's disease
Šírenie patológie asociovanej s alfa-Synukleínom naprieč orgánmi gastrointestinálneho traktu v myšom modeli a pacientov s Parkinsonovou chorobou
| Duration: | 1. 7. 2021 - 30. 6. 2024 |
| Evidence number: | APVV-20-0331 |
| Program: | APVV |
| Project leader: | MUDr. RNDr. Fričová Dominika PhD. |
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Štipendiá pre excelentných výskumníkov ohrozených vojnovým konfliktom na Ukrajine
| Duration: | 15. 3. 2023 - 14. 3. 2026 |
| Evidence number: | 09I03-03-V01-00147 |
| Program: | Iné projekty |
| Project leader: | doc. Hryntsová Natalia Borisovna PhD. |
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Štipendiá pre excelentných výskumníkov ohrozených vojnovým konfliktom na Ukrajine
| Duration: | 15. 10. 2022 - 14. 10. 2025 |
| Evidence number: | 09I03-03-V01-00019 |
| Program: | Iné projekty |
| Project leader: | Lykhota Olena Borysivna PhD. |
Mechanism of tau protein movement through and out of the brain
Štúdium mechanizmu pohybu tau proteínu v CNS
| Duration: | 1. 7. 2022 - 30. 6. 2025 |
| Evidence number: | APVV-21-0321 |
| Program: | APVV |
| Project leader: | PharmDr. Kováč Andrej PhD. |
The role of senescence in neurodegeneration: from the molecular connection to the application and novel treatment strategies
Úloha senescencie v neuurodegenerácii: od molekulárnych mechanizmov po inovatívne stratégie v liečbe
| Duration: | 1. 10. 2021 - 30. 9. 2024 |
| Evidence number: | 1085/01/02 |
| Program: | SASPRO |
| Project leader: | MUDr. RNDr. Fričová Dominika PhD. |
Examining the role of dopamine and adult neurogenesis in learned behavior of songbirds using optogenetic manipulation
Určenie úlohy dopamínu a neurogenézy v dospelosti pre naučené správanie spevavcov pomocou optogenetickej manipulácie
| Duration: | 1. 7. 2021 - 30. 6. 2025 |
| Evidence number: | APVV-20-0344 |
| Program: | APVV |
| Project leader: | MUDr. Mgr. Hromádka Tomáš PhD. |
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Vplyv celkovej anestézie na dynamiku zmien markerov mozgového poškodenia pri operáciách kraniosynostóz v dojčenskom veku
| Duration: | 1. 1. 2023 - 31. 12. 2026 |
| Evidence number: | 1/ 0564/23 |
| Program: | VEGA |
| Project leader: | MUDr. Parrák Vojtech |
The effect of glial cells on tau spreading in neuro-glia cell-based model for Alzheimer’s disease
Vplyv gliových buniek na šírenie tau patológie v neuro-gliovom bunkovom modeli pre Alzheimerovu chorobu
| Duration: | 1. 1. 2022 - 31. 12. 2024 |
| Evidence number: | 2/0134/22 |
| Program: | VEGA |
| Project leader: | RNDr. Žilková Monika PhD. |
Specific structure of tau protein filaments as triggers of diagnostic peripheral biomarkers for diagnostic of chronic traumatic encephalopathy and other tauopathies
Vplyv špecifickej štruktúry filamentov tau proteínu na indukciu periférnych biomarkerov pre diagnostiku chronickej traumatickej encefalopátie a ďalších tauopátií
| Duration: | 1. 1. 2023 - 31. 12. 2026 |
| Evidence number: | 2/0141/23 |
| Program: | VEGA |
| Project leader: | RNDr. Škrabana Rostislav PhD. |
Projects total: 36